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Haozhou Tan
Haozhou Tan
在 scarletmail.rutgers.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Naturally occurring mutations of SARS-CoV-2 main protease confer drug resistance to nirmatrelvir
Y Hu, EM Lewandowski, H Tan, X Zhang, RT Morgan, X Zhang, ...
ACS central science 9 (8), 1658-1669, 2023
1462023
Discovery of di-and trihaloacetamides as covalent SARS-CoV-2 main protease inhibitors with high target specificity
C Ma, Z Xia, MD Sacco, Y Hu, JA Townsend, X Meng, J Choza, H Tan, ...
Journal of the American Chemical Society 143 (49), 20697-20709, 2021
1032021
Progress and challenges in targeting the SARS-CoV-2 papain-like protease
H Tan, Y Hu, P Jadhav, B Tan, J Wang
Journal of medicinal chemistry 65 (11), 7561-7580, 2022
882022
Validation and invalidation of SARS-CoV-2 main protease inhibitors using the Flip-GFP and Protease-Glo luciferase assays
C Ma, H Tan, J Choza, Y Wang, J Wang
Acta Pharmaceutica Sinica B 12 (4), 1636-1651, 2022
592022
SARS-CoV-2 main protease drug design, assay development, and drug resistance studies
B Tan, R Joyce, H Tan, Y Hu, J Wang
Accounts of chemical research 56 (2), 157-168, 2022
452022
An overview of antivirals against monkeypox virus and other orthopoxviruses
J Wang, M Shahed-AI-Mahmud, A Chen, K Li, H Tan, R Joyce
Journal of medicinal chemistry 66 (7), 4468-4490, 2023
162023
Invalidation of dieckol and 1, 2, 3, 4, 6-pentagalloylglucose (PGG) as SARS-CoV-2 main protease inhibitors and the discovery of PGG as a papain-like protease inhibitor
H Tan, C Ma, J Wang
Medicinal Chemistry Research 31 (7), 1147-1153, 2022
152022
Exploring diverse reactive warheads for the design of SARS-CoV-2 main protease inhibitors
B Tan, M Sacco, H Tan, K Li, R Joyce, X Zhang, Y Chen, J Wang
European Journal of Medicinal Chemistry 259, 115667, 2023
112023
A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations
J Ou, EM Lewandowski, Y Hu, AA Lipinski, A Aljasser, M Colon-Ascanio, ...
PLoS pathogens 19 (8), e1011592, 2023
112023
Rational design of a deuterium-containing M2-S31N channel blocker UAWJ280 with in vivo antiviral efficacy against both oseltamivir sensitive and -resistant …
CJ Cáceres, Y Hu, S Cárdenas-García, X Wu, H Tan, S Carnaccini, ...
Emerging Microbes & Infections 10 (1), 1832-1848, 2021
102021
Telaprevir treatment reduces paralysis in a mouse model of enterovirus D68 acute flaccid myelitis
J Frost, MJ Rudy, JS Leser, H Tan, Y Hu, J Wang, P Clarke, KL Tyler
Journal of virology 97 (5), e00156-23, 2023
72023
A benzopyran with antiarrhythmic activity is an inhibitor of Kir3. 1-containing potassium channels
M Cui, Y Alhamshari, L Cantwell, EIH Said, GC Eptaminitaki, M Chang, ...
Journal of Biological Chemistry 296, 2021
72021
Structure-based design of SARS-CoV-2 papain-like protease inhibitors
P Jadhav, B Huang, J Osipiuk, X Zhang, H Tan, C Tesar, M Endres, ...
European Journal of Medicinal Chemistry 264, 116011, 2024
32024
FlipGFP protease assay for evaluating in vitro inhibitory activity against SARS-CoV-2 Mpro and PLpro
H Tan, Y Hu, J Wang
STAR protocols 4 (2), 102323, 2023
32023
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model
B Tan, X Zhang, A Ansari, P Jadhav, H Tan, K Li, A Chopra, A Ford, X Chi, ...
Science 383 (6690), 1434-1440, 2024
22024
Distal Protein-Protein Interactions Contribute to SARS-CoV-2 Main Protease Substrate Binding and Nirmatrelvir Resistance
EM Lewandowski, X Zhang, H Tan, A Jaskolka-Brown, N Kohaal, ...
bioRxiv, 2024.04. 01.587566, 2024
2024
Structure-Based Lead Optimization of Enterovirus D68 2A Protease Inhibitors
B Tan, C Liu, K Li, P Jadhav, G Lambrinidis, L Zhu, L Olson, H Tan, Y Wen, ...
Journal of medicinal chemistry 66 (21), 14544-14563, 2023
2023
Design of SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model (preprint)
B Tan, X Zhang, A Ansari, P Jadhav, H Tan, K Li, A Chopra, A Ford, X Chi, ...
2023
Naturally occurring mutations of SARS-CoV-2 main protease confer drug resistance to nirmatrelvir (preprint)
Y Hu, EM Lewandowski, H Tan, RT Morgan, X Zhang, LM Jacobs, ...
2022
A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations (preprint)
J Ou, E Lewandowski, Y Hu, A Lipinski, R Morgan, L Jacobs, X Zhang, ...
2022
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