Mapping human microbiome drug metabolism by gut bacteria and their genes M Zimmermann, M Zimmermann-Kogadeeva, R Wegmann, AL Goodman Nature 570 (7762), 462-467, 2019 | 886 | 2019 |
Separating host and microbiome contributions to drug pharmacokinetics and toxicity M Zimmermann, M Zimmermann-Kogadeeva, R Wegmann, AL Goodman Science 363 (6427), eaat9931, 2019 | 359 | 2019 |
The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support A Irmisch, X Bonilla, S Chevrier, KV Lehmann, F Singer, NC Toussaint, ... Cancer Cell 39 (3), 288-293, 2021 | 103 | 2021 |
CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data R Wegmann, M Neri, S Schuierer, B Bilican, H Hartkopf, F Nigsch, F Mapa, ... Genome biology 20, 1-21, 2019 | 49 | 2019 |
Ex vivo drug response heterogeneity reveals personalized therapeutic strategies for patients with multiple myeloma K Kropivsek, P Kachel, S Goetze, R Wegmann, Y Festl, Y Severin, ... Nature Cancer 4 (5), 734-753, 2023 | 18 | 2023 |
A functional analysis of 180 cancer cell lines reveals conserved intrinsic metabolic programs S Cherkaoui, S Durot, J Bradley, S Critchlow, S Dubuis, MM Masiero, ... Molecular Systems Biology 18 (11), e11033, 2022 | 18 | 2022 |
ROS induction targets persister cancer cells with low metabolic activity in NRAS-mutated melanoma OM Eichhoff, CI Stoffel, J Käsler, L Briker, P Turko, G Karsai, N Zila, ... Cancer Research 83 (7), 1128-1146, 2023 | 11 | 2023 |
Separating host and microbiome contributions to drug pharmacokinetics and toxicity. Science 363: eaat9931 M Zimmermann, M Zimmermann-Kogadeeva, R Wegmann, AL Goodman | 9 | 2019 |
Targeting tumour-intrinsic neural vulnerabilities of glioblastoma S Lee, T Weiss, M Bühler, J Mena, Z Lottenbach, R Wegmann, M Bihl, ... bioRxiv, 2022.10. 07.511321, 2022 | 2 | 2022 |
Epithelial-mesenchymal transition is the main driver of intrinsic metabolism in cancer cell lines S Cherkaoui, S Durot, J Bradley, S Critchlow, S Dubuis, MM Masiero, ... bioRxiv, 2021.11. 02.466992, 2021 | 1 | 2021 |
The cellular hierarchy of acute myeloid leukemia informs personalized treatment Y Severin, Y Festl, TM Benoit, R Wegmann, BD Hale, M Roiss, ... medRxiv, 2024.07. 24.24310768, 2024 | | 2024 |
SINGLE-CELL FUNCTIONAL TISSUE PROFILING IDENTIFIES PROMISING CANDIDATES FOR DRUG REPURPOSING AGAINST GLIOBLASTOMA T Weiss, S Lee, M Buehler, J Mena, Z Lottenbach, R Wegmann, M Bihl, ... NEURO-ONCOLOGY 25, 2023 | | 2023 |
Functional and molecular tumor profiling for precision oncology R Wegmann ETH Zurich, 2023 | | 2023 |
Long-term history dependence of growth rates of E. coli after nutrient shifts D Christodoulou, A Mukherjee, R Wegmann, A Pagano, V Sharma, ... bioRxiv, 2023 | | 2023 |
ROS induction as a strategy to target persister cancer cells with low metabolic activity in NRAS mutated melanoma OM Eichhoff, CI Stoffel, J Käsler, L Briker, P Turko, G Karsai, N Zila, ... bioRxiv, 2022.10. 19.512839, 2022 | | 2022 |
ROS induction as a strategy to target persister cancer cell metabolism O Eichhoff, C Stoffel, L Briker, P Turko, G Karsai, V Paulitschke, ... European Journal of Cancer 174, S3, 2022 | | 2022 |
Image-based functional precision medicine for repurposing neuroactive drugs in glioblastoma S Lee, T Weiss, M Bühler, R Wegmann, J Mena, M Bihl, S Goetze, ... Cancer Research 82 (12_Supplement), 5325-5325, 2022 | | 2022 |
P856: A SINGLE-CELL FUNCTIONAL PRECISION MEDICINE LANDSCAPE OF MULTIPLE MYELOMA K Kropivsek, P Kachel, S Goetze, R Wegmann, Y Severin, BD Hale, ... HemaSphere 6, 749-750, 2022 | | 2022 |
S134: INTRA-PATIENT FUNCTIONAL HETEROGENEITY OF AML DETERMINES FIRST-LINE TREATMENT RESPONSE Y Severin, Y Festl, M Roiss, T Benoit, T Heinemann, R Wegmann, ... HemaSphere 6, 35-36, 2022 | | 2022 |
Uncovering new therapeutic opportunities for glioblastoma by image-based ex vivo drug-screening S Lee, T Weiss, M Buehler, R Wegmann, J Mena, M Bihl, S Goetze, ... Brain Tumor Research and Treatment 10 (Suppl), 2022 | | 2022 |