| Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial S Ramakrishnan, DV Nicolau, B Langford, M Mahdi, H Jeffers, ... The Lancet Respiratory Medicine 9 (7), 763-772, 2021 | 450 | 2021 |
| Cellular senescence as a mechanism and target in chronic lung diseases PJ Barnes, J Baker, LE Donnelly American journal of respiratory and critical care medicine 200 (5), 556-564, 2019 | 384 | 2019 |
| Oxidative stress dependent microRNA-34a activation via PI3Kα reduces the expression of sirtuin-1 and sirtuin-6 in epithelial cells JR Baker, C Vuppusetty, T Colley, AI Papaioannou, P Fenwick, ... Scientific reports 6 (1), 35871, 2016 | 154 | 2016 |
| MicroRNA-570 is a novel regulator of cellular senescence and inflammaging JR Baker, C Vuppusetty, T Colley, S Hassibi, PS Fenwick, LE Donnelly, ... The FASEB Journal 33 (2), 1605, 2019 | 76 | 2019 |
| The dynamic shuttling of SIRT1 between cytoplasm and nuclei in bronchial epithelial cells by single and repeated cigarette smoke exposure S Yanagisawa, JR Baker, C Vuppusetty, T Koga, T Colley, P Fenwick, ... PloS one 13 (3), e0193921, 2018 | 63 | 2018 |
| Decreased phosphatase PTEN amplifies PI3K signaling and enhances proinflammatory cytokine release in COPD S Yanagisawa, JR Baker, C Vuppusetty, P Fenwick, LE Donnelly, K Ito, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 313 (2 …, 2017 | 57 | 2017 |
| Decreased serum sirtuin-1 in COPD S Yanagisawa, AI Papaioannou, A Papaporfyriou, JR Baker, ... Chest 152 (2), 343-352, 2017 | 57 | 2017 |
| Senotherapy: a new horizon for COPD therapy JR Baker, LE Donnelly, PJ Barnes Chest 158 (2), 562-570, 2020 | 50 | 2020 |
| Early Th2 inflammation in the upper respiratory mucosa as a predictor of severe COVID-19 and modulation by early treatment with inhaled corticosteroids: a mechanistic analysis JR Baker, M Mahdi, DV Nicolau, S Ramakrishnan, PJ Barnes, JL Simpson, ... The Lancet Respiratory Medicine 10 (6), 545-556, 2022 | 46 | 2022 |
| Downregulation of microRNA-126 augments DNA damage response in cigarette smokers and patients with chronic obstructive pulmonary disease KE Paschalaki, A Zampetaki, JR Baker, MA Birrell, RD Starke, MG Belvisi, ... American journal of respiratory and critical care medicine 197 (5), 665-668, 2018 | 43 | 2018 |
| IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice CK Koss, CT Wohnhaas, JR Baker, C Tilp, M Przibilla, C Lerner, S Frey, ... Communications biology 4 (1), 172, 2021 | 40 | 2021 |
| Protein kinase D3 modulates MMP1 and MMP13 expression in human chondrocytes J Baker, AMD Falconer, DJ Wilkinson, GN Europe-Finner, GJ Litherland, ... PLoS One 13 (4), e0195864, 2018 | 34 | 2018 |
| Cigarette smoke-induced impairment of autophagy in macrophages increases galectin-8 and inflammation Y Kono, T Colley, M To, AI Papaioannou, N Mercado, JR Baker, Y To, ... Scientific reports 11 (1), 335, 2021 | 28 | 2021 |
| Update in chronic obstructive pulmonary disease 2019 P Alter, JR Baker, N Dauletbaev, LE Donnelly, C Pistenmaa, B Schmeck, ... American journal of respiratory and critical care medicine 202 (3), 348-355, 2020 | 27 | 2020 |
| Autophagy in asthma and chronic obstructive pulmonary disease PJ Barnes, J Baker, LE Donnelly Clinical Science 136 (10), 733-746, 2022 | 26 | 2022 |
| Hepcidin is essential for alveolar macrophage function and is disrupted by smoke in a murine chronic obstructive pulmonary disease model E Perez, JR Baker, S Di Giandomenico, P Kermani, J Parker, K Kim, ... The Journal of Immunology 205 (9), 2489-2498, 2020 | 15 | 2020 |
| Bicaudal D1 impairs autophagosome maturation in chronic obstructive pulmonary disease N Mercado, T Colley, JR Baker, C Vuppussetty, Y Kono, C Clarke, ... FASEB bioAdvances 1 (11), 688, 2019 | 15 | 2019 |
| IL-36 receptor agonist and antagonist imbalance drives neutrophilic inflammation in COPD JR Baker, PS Fenwick, CK Koss, HB Owles, SL Elkin, J Fine, M Thomas, ... JCI insight 7 (15), 2022 | 14 | 2022 |
| Leukocyte function in COPD: clinical relevance and potential for drug therapy JR Baker, LE Donnelly International Journal of Chronic Obstructive Pulmonary Disease, 2227-2242, 2021 | 12 | 2021 |
| Virus-induced asthma exacerbations: SIRT1 targeted approach Y Fukuda, K Akimoto, T Homma, JR Baker, K Ito, PJ Barnes, H Sagara Journal of Clinical Medicine 9 (8), 2623, 2020 | 12 | 2020 |
