Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions AC Fahed, M Wang, JR Homburger, AP Patel, AG Bick, CL Neben, C Lai, ... Nature communications 11 (1), 3635, 2020 | 336 | 2020 |
Lp (a)(lipoprotein [a]) concentrations and incident atherosclerotic cardiovascular disease: new insights from a large national biobank AP Patel, M Wang, JP Pirruccello, PT Ellinor, K Ng, S Kathiresan, ... Arteriosclerosis, thrombosis, and vascular biology 41 (1), 465-474, 2021 | 256 | 2021 |
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants KG Aragam, T Jiang, A Goel, S Kanoni, BN Wolford, DS Atri, EM Weeks, ... Nature genetics 54 (12), 1803-1815, 2022 | 242 | 2022 |
Association of habitual alcohol intake with risk of cardiovascular disease KJ Biddinger, CA Emdin, ME Haas, M Wang, G Hindy, PT Ellinor, ... JAMA network open 5 (3), e223849-e223849, 2022 | 220 | 2022 |
Polygenic basis and biomedical consequences of telomere length variation V Codd, Q Wang, E Allara, C Musicha, S Kaptoge, S Stoma, T Jiang, ... Nature genetics 53 (10), 1425-1433, 2021 | 198 | 2021 |
Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy JP Pirruccello, A Bick, M Wang, M Chaffin, S Friedman, J Yao, X Guo, ... Nature communications 11 (1), 2254, 2020 | 170 | 2020 |
Quantifying and understanding the higher risk of atherosclerotic cardiovascular disease among South Asian individuals: results from the UK Biobank prospective cohort study AP Patel, M Wang, U Kartoun, K Ng, AV Khera Circulation 144 (6), 410-422, 2021 | 98 | 2021 |
Validation of a genome-wide polygenic score for coronary artery disease in South Asians M Wang, R Menon, S Mishra, AP Patel, M Chaffin, D Tanneeru, ... Journal of the American College of Cardiology 76 (6), 703-714, 2020 | 87 | 2020 |
Association of rare pathogenic DNA variants for familial hypercholesterolemia, hereditary breast and ovarian cancer syndrome, and lynch syndrome with disease risk in adults … AP Patel, M Wang, AC Fahed, H Mason-Suares, D Brockman, R Pelletier, ... JAMA network open 3 (4), e203959-e203959, 2020 | 85 | 2020 |
Machine learning enables new insights into genetic contributions to liver fat accumulation ME Haas, JP Pirruccello, SN Friedman, M Wang, CA Emdin, VH Ajmera, ... Cell genomics 1 (3), 2021 | 70 | 2021 |
Disease-causing mutation in α-actinin-4 promotes podocyte detachment through maladaptation to periodic stretch D Feng, J Notbohm, A Benjamin, S He, M Wang, LH Ang, M Bantawa, ... Proceedings of the National Academy of Sciences 115 (7), 1517-1522, 2018 | 62 | 2018 |
Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots S Agrawal, M Wang, MDR Klarqvist, K Smith, J Shin, H Dashti, N Diamant, ... Nature communications 13 (1), 3771, 2022 | 60 | 2022 |
A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease AP Patel, M Wang, Y Ruan, S Koyama, SL Clarke, X Yang, C Tcheandjieu, ... Nature Medicine 29 (7), 1793-1803, 2023 | 52 | 2023 |
UBD modifies APOL1-induced kidney disease risk JY Zhang, M Wang, L Tian, G Genovese, P Yan, JG Wilson, R Thadhani, ... Proceedings of the National Academy of Sciences 115 (13), 3446-3451, 2018 | 52 | 2018 |
Contributions of rare gene variants to familial and sporadic FSGS M Wang, J Chun, G Genovese, AU Knob, A Benjamin, MS Wilkins, ... Journal of the American Society of Nephrology 30 (9), 1625-1640, 2019 | 48 | 2019 |
Rare genetic variants associated with sudden cardiac death in adults AV Khera, H Mason-Suares, D Brockman, M Wang, MJ VanDenburgh, ... Journal of the American College of Cardiology 74 (21), 2623-2634, 2019 | 37 | 2019 |
APOL1-associated kidney disease in Brazil C Riella, TA Siemens, M Wang, RP Campos, TP Moraes, LV Riella, ... Kidney international reports 4 (7), 923-929, 2019 | 31 | 2019 |
Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes G Hindy, P Dornbos, MD Chaffin, DJ Liu, M Wang, MS Selvaraj, D Zhang, ... The American Journal of Human Genetics 109 (1), 81-96, 2022 | 28 | 2022 |
Association of the interaction between familial hypercholesterolemia variants and adherence to a healthy lifestyle with risk of coronary artery disease AC Fahed, M Wang, AP Patel, E Ajufo, DJ Maamari, KG Aragam, ... JAMA network open 5 (3), e222687-e222687, 2022 | 27 | 2022 |
Detecting recent positive selection with high accuracy and reliability by conditional coalescent tree M Wang, X Huang, R Li, H Xu, L Jin, Y He Molecular biology and evolution 31 (11), 3068-3080, 2014 | 26 | 2014 |