| Polyamidoamine dendrimers-based nanomedicine for combination therapy with siRNA and chemotherapeutics to overcome multidrug resistance J Pan, LP Mendes, M Yao, N Filipczak, S Garai, GA Thakur, C Sarisozen, ... European Journal of Pharmaceutics and Biopharmaceutics 136, 18-28, 2019 | 100 | 2019 |
| Positive Allosteric Modulation of CB1 Cannabinoid Receptor Signaling Enhances Morphine Antinociception and Attenuates Morphine Tolerance Without … RA Slivicki, V Iyer, SS Mali, S Garai, GA Thakur, JD Crystal, AG Hohmann Frontiers in Molecular Neuroscience 13, 54, 2020 | 56 | 2020 |
| Scalable, one-pot, microwave-accelerated tandem synthesis of unsymmetrical urea derivatives AR Kulkarni, S Garai, GA Thakur The Journal of organic chemistry 82 (2), 992-999, 2017 | 56 | 2017 |
| Application of fluorine-and nitrogen-walk approaches: defining the structural and functional diversity of 2-phenylindole class of cannabinoid 1 receptor positive allosteric … S Garai, PM Kulkarni, PC Schaffer, LM Leo, AL Brandt, A Zagzoog, ... Journal of medicinal chemistry 63 (2), 542-568, 2019 | 50 | 2019 |
| Identification of CB1 receptor allosteric sites using force-biased MMC simulated annealing and validation by structure–activity relationship studies DP Hurst, S Garai, PM Kulkarni, PC Schaffer, PH Reggio, GA Thakur ACS medicinal chemistry letters 10 (8), 1216-1221, 2019 | 39 | 2019 |
| The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents Y Xu, L Cantwell, AI Molosh, LD Plant, D Gazgalis, SD Fitz, ET Dustrude, ... Journal of Biological Chemistry 295 (11), 3614-3634, 2020 | 29 | 2020 |
| Positive allosteric modulation of type 1 cannabinoid receptors reduces spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg AJ Roebuck, Q Greba, AM Smolyakova, M Alaverdashvili, WN Marks, ... Neuropharmacology 190, 108553, 2021 | 27 | 2021 |
| Allosteric agonism of α7 nicotinic acetylcholine receptors: Receptor modulation outside the orthosteric site A Gulsevin, RL Papke, C Stokes, S Garai, GA Thakur, M Quadri, ... Molecular pharmacology 95 (6), 606-614, 2019 | 26 | 2019 |
| Asymmetric total synthesis of (−)-venlafaxine using an organocatalyst SP Chavan, S Garai, KP Pawar Tetrahedron Letters 54 (17), 2137-2139, 2013 | 24 | 2013 |
| Discovery of a biased allosteric modulator for cannabinoid 1 receptor: preclinical anti-glaucoma efficacy S Garai, LM Leo, AM Szczesniak, DP Hurst, PC Schaffer, A Zagzoog, ... Journal of Medicinal Chemistry 64 (12), 8104-8126, 2021 | 23 | 2021 |
| Macroscopic and microscopic activation of α7 nicotinic acetylcholine receptors by the structurally unrelated allosteric agonist-positive allosteric modulators (ago-PAMs) B-973B … M Quadri, S Garai, GA Thakur, C Stokes, A Gulsevin, NA Horenstein, ... Molecular pharmacology 95 (1), 43-61, 2019 | 23 | 2019 |
| Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4, 5-bisphosphate (PIP2) J Ha, Y Xu, T Kawano, T Hendon, L Baki, S Garai, A Papapetropoulos, ... Journal of Biological Chemistry 293 (10), 3546-3561, 2018 | 20 | 2018 |
| B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation S Garai, KS Raja, RL Papke, JR Deschamps, MI Damaj, GA Thakur ACS Medicinal Chemistry Letters 9 (11), 1144-1148, 2018 | 16 | 2018 |
| Design and synthesis of cannabinoid 1 receptor (CB1R) allosteric modulators: drug discovery applications AR Kulkarni, S Garai, DR Janero, GA Thakur Methods in Enzymology 593, 281-315, 2017 | 15 | 2017 |
| Differing activity profiles of the stereoisomers of 2, 3, 5, 6TMP-TQS, a putative silent allosteric modulator of α7 nAChR RL Papke, S Garai, C Stokes, NA Horenstein, AD Zimmerman, ... Molecular Pharmacology 98 (4), 292-302, 2020 | 13 | 2020 |
| Microwave‐accelerated conjugate addition of 2‐arylindoles to substituted β‐nitrostyrenes in the presence of ammonium trifluoroacetate: An efficient approach for the synthesis … PM Kulkarni, A Ranade, S Garai, GA Thakur Journal of Heterocyclic Chemistry 54 (3), 2079-2084, 2017 | 13 | 2017 |
| A protecting group free and scalable approach towards total synthesis of (−)-venlafaxine SP Chavan, KP Pawar, S Garai RSC Advances 4 (28), 14468-14470, 2014 | 13 | 2014 |
| The endocannabinoid system impacts seizures in a mouse model of Dravet syndrome LL Anderson, PT Doohan, NA Hawkins, D Bahceci, S Garai, GA Thakur, ... Neuropharmacology 205, 108897, 2022 | 12 | 2022 |
| Allosterically potentiated α7 nicotinic acetylcholine receptors: reduced calcium permeability and current-independent control of intracellular calcium DR Miller, H Khoshbouei, S Garai, LN Cantwell, C Stokes, G Thakur, ... Molecular Pharmacology 98 (6), 695-709, 2020 | 12 | 2020 |
| Heteromeric neuronal nicotinic acetylcholine receptors with mutant β subunits acquire sensitivity to α7-selective positive allosteric modulators C Stokes, S Garai, AR Kulkarni, LN Cantwell, CM Noviello, RE Hibbs, ... Journal of Pharmacology and Experimental Therapeutics 370 (2), 252-268, 2019 | 11 | 2019 |
Ganesh ThakurNortheastern University在 neu.edu 的电子邮件经过验证
