| Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials TL Yeh, TM Leissing, MI Abboud, CC Thinnes, O Atasoylu, JP Holt-Martyn, ... Chemical science 8 (11), 7651-7668, 2017 | 207 | 2017 |
| Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases R Chowdhury, IKH Leung, YM Tian, MI Abboud, W Ge, C Domene, ... Nature communications 7 (1), 12673, 2016 | 130 | 2016 |
| The road to avibactam: the first clinically useful non-β-lactam working somewhat like a β-lactam DY Wang, MI Abboud, MS Markoulides, J Brem, CJ Schofield Future medicinal chemistry 8 (10), 1063-1084, 2016 | 125 | 2016 |
| Interaction of avibactam with class B metallo-β-lactamases MI Abboud, C Damblon, J Brem, N Smargiasso, P Mercuri, B Gilbert, ... Antimicrobial agents and chemotherapy 60 (10), 5655-5662, 2016 | 112 | 2016 |
| Targeting protein–protein interactions in the HIF system SE Wilkins, MI Abboud, RL Hancock, CJ Schofield ChemMedChem 11 (8), 773-786, 2016 | 101 | 2016 |
| Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates ME Cockman, K Lippl, YM Tian, HB Pegg, WD Figg, MI Abboud, R Heilig, ... Elife 8, e46490, 2019 | 86 | 2019 |
| NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors GB Li, MI Abboud, J Brem, H Someya, CT Lohans, SY Yang, J Spencer, ... Chemical Science 8 (2), 928-937, 2017 | 76 | 2017 |
| Carcinogenic and neurotoxic risks of acrylamide and heavy metals from potato and corn chips consumed by the Lebanese population E Hariri, MI Abboud, S Demirdjian, S Korfali, M Mroueh, RI Taleb Journal of Food Composition and Analysis 42, 91-97, 2015 | 73 | 2015 |
| Anion-exchange chromatography mass spectrometry provides extensive coverage of primary metabolic pathways revealing altered metabolism in IDH1 mutant cells J Walsby-Tickle, J Gannon, I Hvinden, C Bardella, MI Abboud, A Nazeer, ... Communications biology 3 (1), 247, 2020 | 71 | 2020 |
| Comparison of Verona integron-borne metallo-β-lactamase (VIM) variants reveals differences in stability and inhibition profiles A Makena, AÖ Düzgün, J Brem, MA McDonough, AM Rydzik, MI Abboud, ... Antimicrobial agents and chemotherapy 60 (3), 1377-1384, 2016 | 63 | 2016 |
| Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate Z Zhang, TJ Smart, H Choi, F Hardy, CT Lohans, MI Abboud, ... Proceedings of the National Academy of Sciences 114 (18), 4667-4672, 2017 | 53 | 2017 |
| In silico fragment-based design identifies subfamily B1 metallo-β-lactamase inhibitors R Cain, J Brem, D Zollman, MA McDonough, RM Johnson, J Spencer, ... Journal of Medicinal Chemistry 61 (3), 1255-1260, 2018 | 48 | 2018 |
| Carcinogenic and neurotoxic risks of acrylamide consumed through caffeinated beverages among the lebanese population GEZ Naous, A Merhi, MI Abboud, M Mroueh, RI Taleb Chemosphere 208, 352-357, 2018 | 43 | 2018 |
| The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases S Markolovic, Q Zhuang, SE Wilkins, CD Eaton, MI Abboud, MJ Katz, ... Nature chemical biology 14 (7), 688-695, 2018 | 39 | 2018 |
| Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition GB Li, J Brem, R Lesniak, MI Abboud, CT Lohans, IJ Clifton, SY Yang, ... Chemical communications 53 (43), 5806-5809, 2017 | 34 | 2017 |
| Normal tissue radioprotection by amifostine via Warburg-type effects MI Koukourakis, A Giatromanolaki, CE Zois, D Kalamida, S Pouliliou, ... Scientific reports 6 (1), 30986, 2016 | 33 | 2016 |
| Cyclobutanone mimics of intermediates in metallo‐β‐lactamase catalysis MI Abboud, M Kosmopoulou, AP Krismanich, JW Johnson, P Hinchliffe, ... Chemistry–A European Journal 24 (22), 5734-5737, 2018 | 32 | 2018 |
| A diverse view of science to catalyse change CA Urbina-Blanco, SZ Jilani, IR Speight, MJ Bojdys, T Friščić, JF Stoddart, ... Nature Chemistry, 1-4, 2020 | 31 | 2020 |
| Non-competitive cyclic peptides for targeting enzyme–substrate complexes TE McAllister, TL Yeh, MI Abboud, IKH Leung, ES Hookway, ONF King, ... Chemical Science 9 (20), 4569-4578, 2018 | 31 | 2018 |
| JMJD6 is a druggable oxygenase that regulates AR-V7 expression in prostate cancer A Paschalis, J Welti, AJ Neeb, W Yuan, I Figueiredo, R Pereira, A Ferreira, ... Cancer research 81 (4), 1087-1100, 2022 | 30 | 2022 |
