DNA repair network analysis reveals shieldin as a key regulator of NHEJ and PARP inhibitor sensitivity R Gupta, K Somyajit, T Narita, E Maskey, A Stanlie, M Kremer, D Typas, ... Cell 173 (4), 972-988. e23, 2018 | 446 | 2018 |
Structural and mechanistic insights into the interaction between Rho and mammalian Dia R Rose, M Weyand, M Lammers, T Ishizaki, MR Ahmadian, A Wittinghofer Nature 435 (7041), 513-518, 2005 | 339 | 2005 |
The regulation of mDia1 by autoinhibition and its release by Rho• GTP M Lammers, R Rose, A Scrima, A Wittinghofer The EMBO journal 24 (23), 4176-4187, 2005 | 206 | 2005 |
Specificity of interactions between mDia isoforms and Rho proteins M Lammers, S Meyer, D Kuhlmann, A Wittinghofer Journal of Biological Chemistry 283 (50), 35236-35246, 2008 | 158 | 2008 |
Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation BK Hansen, R Gupta, L Baldus, D Lyon, T Narita, M Lammers, ... Nature communications 10 (1), 1055, 2019 | 146 | 2019 |
Acetylation regulates cyclophilin A catalysis, immunosuppression and HIV isomerization M Lammers, H Neumann, JW Chin, LC James Nature chemical biology 6 (5), 331-337, 2010 | 130 | 2010 |
Active site remodeling switches HIV specificity of antiretroviral TRIMCyp AJ Price, F Marzetta, M Lammers, LMJ Ylinen, T Schaller, SJ Wilson, ... Nature structural & molecular biology 16 (10), 1036-1042, 2009 | 111 | 2009 |
Multiple substrate binding mode-guided engineering of a thermophilic PET hydrolase L Pfaff, J Gao, Z Li, A Jäckering, G Weber, J Mican, Y Chen, W Dong, ... ACS catalysis 12 (15), 9790-9800, 2022 | 82 | 2022 |
Small GTP-binding protein Ran is regulated by posttranslational lysine acetylation S de Boor, P Knyphausen, N Kuhlmann, S Wroblowski, J Brenig, ... Proceedings of the National Academy of Sciences 112 (28), E3679-E3688, 2015 | 76 | 2015 |
Acetylation regulates ribonucleotide reductase activity and cancer cell growth G Chen, Y Luo, K Warncke, Y Sun, DS Yu, H Fu, M Behera, ... Nature communications 10 (1), 3213, 2019 | 64 | 2019 |
Insights into lysine deacetylation of natively folded substrate proteins by sirtuins P Knyphausen, S de Boor, N Kuhlmann, L Scislowski, A Extra, L Baldus, ... Journal of Biological Chemistry 291 (28), 14677-14694, 2016 | 54 | 2016 |
Structural and mechanistic insights into the regulation of the fundamental Rho regulator RhoGDIα by lysine acetylation N Kuhlmann, S Wroblowski, P Knyphausen, S de Boor, J Brenig, ... Journal of Biological Chemistry 291 (11), 5484-5499, 2016 | 54 | 2016 |
Sequence‐based prediction of promiscuous acyltransferase activity in hydrolases H Müller, AK Becker, GJ Palm, L Berndt, CPS Badenhorst, SP Godehard, ... Angewandte Chemie 132 (28), 11704-11709, 2020 | 50 | 2020 |
A KRAS GTPase K104Q mutant retains downstream signaling by offsetting defects in regulation G Yin, S Kistler, SD George, N Kuhlmann, L Garvey, M Huynh, RK Bagni, ... Journal of Biological Chemistry 292 (11), 4446-4456, 2017 | 44 | 2017 |
Structural insights into (tere) phthalate-ester hydrolysis by a carboxylesterase and its role in promoting PET depolymerization G von Haugwitz, X Han, L Pfaff, Q Li, H Wei, J Gao, K Methling, Y Ao, ... ACS catalysis 12 (24), 15259-15270, 2022 | 42 | 2022 |
Lysine acetylation regulates the interaction between proteins and membranes AK Okada, K Teranishi, MR Ambroso, JM Isas, E Vazquez-Sarandeses, ... Nature Communications 12 (1), 6466, 2021 | 37 | 2021 |
Discovery and design of family VIII carboxylesterases as highly efficient acyltransferases H Müller, SP Godehard, GJ Palm, L Berndt, CPS Badenhorst, AK Becker, ... Angewandte Chemie International Edition 60 (4), 2013-2017, 2021 | 33 | 2021 |
Insights into K-Ras 4B regulation by post-translational lysine acetylation P Knyphausen, F Lang, L Baldus, A Extra, M Lammers Biological chemistry 397 (10), 1071-1085, 2016 | 33 | 2016 |
An evolutionary approach to systematic discovery of novel deubiquitinases, applied to Legionella T Hermanns, I Woiwode, RFM Guerreiro, R Vogt, M Lammers, K Hofmann Life Science Alliance 3 (9), 2020 | 30 | 2020 |
Autophagy lipidation machinery regulates axonal microtubule dynamics but is dispensable for survival of mammalian neurons A Negrete-Hurtado, M Overhoff, S Bera, E De Bruyckere, K Schätzmüller, ... Nature communications 11 (1), 1535, 2020 | 29 | 2020 |