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Kilian L Kleemann
Kilian L Kleemann
PhD Student, Bonn University
在 uni-bonn.de 的电子邮件经过验证
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APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
Z Yin, N Rosenzweig, KL Kleemann, X Zhang, W Brandão, MA Margeta, ...
Nature immunology 24 (11), 1839-1853, 2023
802023
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease
Z Yin, S Herron, S Silveira, K Kleemann, C Gauthier, D Mallah, Y Cheng, ...
Nature neuroscience 26 (7), 1196-1207, 2023
572023
Disease-associated astrocyte epigenetic memory promotes CNS pathology
HG Lee, JM Rone, Z Li, CF Akl, SW Shin, JH Lee, LE Flausino, F Pernin, ...
Nature 627 (8005), 865-872, 2024
262024
Interrelations of Alzheimer´ s disease candidate biomarkers neurogranin, fatty acid‐binding protein 3 and ferritin to neurodegeneration and neuroinflammation
F Brosseron, K Kleemann, CC Kolbe, F Santarelli, S Castro‐Gomez, ...
Journal of neurochemistry 157 (6), 2210-2224, 2021
212021
Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease
N Rosenzweig, KL Kleemann, T Rust, M Carpenter, M Grucci, M Aronchik, ...
Nature Medicine 30 (10), 2990-3003, 2024
92024
Radial glia promote microglial development through integrin αVβ8-TGFβ1 signaling
GL McKinsey, N Santander, X Zhang, K Kleemann, L Tran, A Katewa, ...
BioRxiv, 2023
32023
Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy
W Brandao, N Jain, Z Yin, KL Kleemann, M Carpenter, X Bao, JR Serrano, ...
Science Translational Medicine 17 (781), eadk3690, 2025
2025
Neuroinflammation in Alzheimer disease
Nature Reviews Immunology, 2024
2024
Exploring how APOE ε4 increases Alzheimer’s disease risk in women
GAS Inglis
Nature Aging 4 (8), 1032-1032, 2024
2024
APOE4 puts breaks on neutrophil-microglia crosstalk to accelerate Alzheimer’s disease
N Rosenzweig, KL Kleemann, M Grucci, M Aronchik, O Butovsky
Alzheimer's Association International Conference, 2024
2024
APOE‐4 dependent dysfunctional neutrophil‐microglia crosstalk accelerates Alzheimer’s disease
N Rosenzweig, K Kleemann, M Grucci, M Aronchik, O Butovsky
Alzheimer's & Dementia 19, e075072, 2023
2023
Deletion of miR‐155 in microglia enhances their response to neurodegeneration and mitigates cognitive impairment in a mouse model of Alzheimer’s disease
Z Yin, S Herron, S Silveira, K Kleemann, C Gauthier, D Mallah, C Cheng, ...
Alzheimer's & Dementia 19, e076703, 2023
2023
APOE4 impairs Microglia‐Astrocyte Crosstalk in Alzheimer Disease
K Kleemann, N Rosenzweig, Z Yin, X Zhang, WN Brandao, M Margeta, ...
Alzheimer's & Dementia 19, e071852, 2023
2023
APOE4 impairs microglia‐astrocyte response in Alzheimer’s disease by inducing TGFβ‐mediated checkpoints
O Butovsky, Z Yin, N Rosenzweig, K Kleemann, X Zhang, WN Brandao, ...
Alzheimer's & Dementia 19, e076510, 2023
2023
Xenon gas (Xe) treatment to restore microglial functions in Alzheimer’s disease (AD)
WN Brandao, Z Yin, K Kleemann, X Zhang, N Rosenzweig, N Jain, ...
Alzheimer's & Dementia 19, e076467, 2023
2023
Suppressing ApoE ε4 allele protects against signs of Alzheimer’s disease
Z Yin, N Rosenzweig, KL Kleemann, X Zhang, W Brandão, MA Margeta, ...
2023
Radial glia control microglial differentiation via integrin avb8-dependent trans-activation of TGFB1
GL McKinsey, N Santander, X Zhang, K Kleemann, A Katewa, L Tran, ...
2023
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