| Inflammation as a regulator of the renin-angiotensin system and blood pressure R Satou, H Penrose, LG Navar Current hypertension reports 20, 1-9, 2018 | 166 | 2018 |
| Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6 H Penrose, S Heller, C Cable, R Makboul, G Chadalawada, Y Chen, ... Biochemical and biophysical research communications 469 (3), 370-376, 2016 | 51 | 2016 |
| High-fat diet induced leptin and Wnt expression: RNA-sequencing and pathway analysis of mouse colonic tissue and tumors HM Penrose, S Heller, C Cable, H Nakhoul, M Baddoo, E Flemington, ... Carcinogenesis 38 (3), 302-311, 2017 | 44 | 2017 |
| Reduced mitochondrial activity in colonocytes facilitates AMPKα2-dependent inflammation S Heller, HM Penrose, C Cable, D Biswas, H Nakhoul, M Baddoo, ... The FASEB Journal 31 (5), 2013, 2017 | 39 | 2017 |
| VSL# 3 probiotic stimulates T-cell protein tyrosine phosphatase–mediated recovery of IFN-γ–induced intestinal epithelial barrier defects M Krishnan, HM Penrose, NN Shah, RR Marchelletta, DF McCole Inflammatory bowel diseases 22 (12), 2811-2823, 2016 | 39 | 2016 |
| Loss of Forkhead Box O3 Facilitates Inflammatory Colon Cancer: Transcriptome Profiling of the Immune Landscape and Novel Targets HM Penrose, C Cable, S Heller, N Ungerleider, H Nakhoul, M Baddoo, ... Cellular and molecular gastroenterology and hepatology, 2018 | 38 | 2018 |
| Macrophage-derived IL-6 contributes to ANG II-mediated angiotensinogen stimulation in renal proximal tubular cells R O'Leary, H Penrose, K Miyata, R Satou American Journal of Physiology-Renal Physiology 310 (10), F1000-F1007, 2016 | 37 | 2016 |
| Spermidine stimulates T cell protein-tyrosine phosphatase-mediated protection of intestinal epithelial barrier function HM Penrose, RR Marchelletta, M Krishnan, DF McCole Journal of Biological Chemistry 288 (45), 32651-32662, 2013 | 31 | 2013 |
| Intestinal inflammation requires FOXO3 and prostaglandin E2-dependent lipogenesis and elevated lipid droplets S Heller, C Cable, H Penrose, R Makboul, D Biswas, M Cabe, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 310 (10 …, 2016 | 27 | 2016 |
| Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy HM Penrose, R Iftikhar, ME Collins, E Toraih, E Ruiz, N Ungerleider, ... Scientific Reports 11 (1), 9010, 2021 | 23 | 2021 |
| Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity R Iftikhar, HM Penrose, AN King, JS Samudre, ME Collins, AB Hartono, ... Oncogenesis 10 (11), 82, 2021 | 20 | 2021 |
| Bacterial TLR4 and NOD2 signaling linked to reduced mitochondrial energy function in active inflammatory bowel disease E Ruiz, HM Penrose, S Heller, H Nakhoul, M Baddoo, EF Flemington, ... Gut microbes 11 (3), 350-363, 2020 | 17 | 2020 |
| A comparison of linaclotide and lubiprostone dosing regimens on ion transport responses in human colonic mucosa SB Kang, RR Marchelletta, H Penrose, MJ Docherty, DF McCole Pharmacology Research & Perspectives 3 (2), e00128, 2015 | 11 | 2015 |
| In colonic ρ0 (rho0) cells reduced mitochondrial function mediates transcriptomic alterations associated with cancer HM Penrose, S Heller, C Cable, H Nakhoul, N Ungerleider, M Baddoo, ... Oncoscience 4 (11-12), 189, 2017 | 9 | 2017 |
| FOXO3 expression in macrophages is lowered by a high-fat diet and regulates colonic inflammation and tumorigenesis R Iftikhar, HM Penrose, AN King, Y Kim, E Ruiz, E Kandil, HL Machado, ... Metabolites 12 (3), 250, 2022 | 8 | 2022 |
| Trends in the incidence of early-onset colorectal adenocarcinoma among black and white US residents aged 40 to 49 years, 2000-2017 EM Montminy, M Zhou, L Maniscalco, H Penrose, T Yen, SG Patel, XC Wu, ... JAMA Network Open 4 (11), e2130433-e2130433, 2021 | 8 | 2021 |
| FOXO3 deficiency in neutrophils drives colonic inflammation and tumorigenesis J Ghimire, R Iftikhar, HM Penrose, P Snarski, E Ruiz, SD Savkovic International Journal of Molecular Sciences 24 (11), 9730, 2023 | 4 | 2023 |
| The Clc-2 chloride channel activator, lubiprostone, improves intestinal barrier function in biopsies from crohn’s disease but not ulcerative colitis patients YS Park, SB Kang, RR Marchelletta, HM Penrose, R Ruiter-Visser, B Jung, ... Pharmaceutics 15 (3), 811, 2023 | 3 | 2023 |
| Tu1980 Low Mitochondrial Activity in Colon Cancer Cells via Loss of FOXO3 Elevates Intracellular Lipid Droplets (LDs) to Accelerate Proliferation S Heller, C Cable, HM Penrose, S Crawford, SD Savkovic Gastroenterology 148 (4), S-951-S-952, 2015 | 3 | 2015 |
| STAT1 regulates interferon-γ-induced angiotensinogen and MCP-1 expression in a bidirectional manner in primary cultured mesangial cells HM Penrose, A Katsurada, K Miyata, M Urushihara, R Satou Journal of the Renin-Angiotensin-Aldosterone System 21 (3), 1470320320946527, 2020 | 2 | 2020 |
Susan E CrawfordNorthShore University Research Institute, Affiliate of University of Chicago Pritzker School of在 uchicago.edu 的电子邮件经过验证
