Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook S Shukla, CS Sumaria, PI Pradeepkumar ChemMedChem 5 (3), 328-349, 2010 | 236 | 2010 |
Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects S Shukla, JC Schmidt, KC Goldfarb, TR Cech, R Parker Nature structural & molecular biology 23 (4), 286, 2016 | 129 | 2016 |
Hypo-and hyper-assembly diseases of RNA–protein complexes S Shukla, R Parker Trends in molecular medicine 22 (7), 615-628, 2016 | 71 | 2016 |
The RNase PARN controls the levels of specific miRNAs that contribute to p53 regulation S Shukla, GA Bjerke, D Muhlrad, R Yi, R Parker Molecular cell 73 (6), 1204-1216. e4, 2019 | 68 | 2019 |
Quality control of assembly-defective U1 snRNAs by decapping and 5′-to-3′ exonucleolytic digestion S Shukla, R Parker Proceedings of the National Academy of Sciences 111 (32), E3277-E3286, 2014 | 57 | 2014 |
PARN modulates Y RNA stability and its 3′-end formation S Shukla, R Parker Molecular and Cellular Biology 37 (20), e00264-17, 2017 | 39 | 2017 |
Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita WC Fok, S Shukla, AT Vessoni, KA Brenner, R Parker, CM Sturgeon, ... Blood, The Journal of the American Society of Hematology 133 (12), 1308-1312, 2019 | 37 | 2019 |
Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita S Shukla, HC Jeong, CM Sturgeon, R Parker, LFZ Batista Blood advances 4 (12), 2717-2722, 2020 | 35 | 2020 |
USB1 is a miRNA deadenylase that regulates hematopoietic development HC Jeong, S Shukla, WC Fok, TN Huynh, LFZ Batista, R Parker Science 379 (6635), 901-907, 2023 | 16 | 2023 |
Identification of PARN nuclease activity inhibitors by computational-based docking and high-throughput screening TN Huynh, S Shukla, P Reigan, R Parker Scientific Reports 13 (1), 5244, 2023 | 1 | 2023 |
PAPD5 Inhibition As A Treatment For Dyskeratosis Congenita, Aplastic Anemia And Myelodysplastic Syndrome Caused By Reduced Telomerase RNA Levels RR Parker, S Shukla, LFZ Batista, H Jeong US Patent App. 17/775,133, 2022 | | 2022 |
Usb1 Directed Regulation Of Mirnas Related Hematopoietic Differentiation And Affected In Multiple Forms Of Leukemia RR Parker, S Shukla, LFZ Batista, H Jeong US Patent App. 17/466,448, 2022 | | 2022 |
USB1 Is a miRNA Deadenylase That Regulates Hematopoietic Development HC Jeong, S Shukla, R Parker, L Batista Blood 138, 2191, 2021 | | 2021 |
Parn as a biomarker and therapeutic target RR PARKER, S Shukla | | 2020 |
Investigation of RNA Quality Control Pathways in RNP Hypo-Assembly Diseases S Shukla | | 2016 |