| Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds D Huangfu, R Maehr, W Guo, A Eijkelenboom, M Snitow, AE Chen, ... Nature biotechnology 26 (7), 795-797, 2008 | 2159 | 2008 |
| Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2 D Huangfu, K Osafune, R Maehr, W Guo, A Eijkelenboom, S Chen, ... Nature biotechnology 26 (11), 1269-1275, 2008 | 1910 | 2008 |
| Functional annotation of native enhancers with a Cas9–histone demethylase fusion NA Kearns, H Pham, B Tabak, RM Genga, NJ Silverstein, M Garber, ... Nature methods 12 (5), 401-403, 2015 | 820 | 2015 |
| Generation of pluripotent stem cells from patients with type 1 diabetes R Maehr, S Chen, M Snitow, T Ludwig, L Yagasaki, R Goland, RL Leibel, ... Proceedings of the National Academy of Sciences 106 (37), 15768-15773, 2009 | 809 | 2009 |
| The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc PL Greer, R Hanayama, BL Bloodgood, AR Mardinly, DM Lipton, ... Cell 140 (5), 704-716, 2010 | 717 | 2010 |
| A small molecule that directs differentiation of human ESCs into the pancreatic lineage S Chen, M Borowiak, JL Fox, R Maehr, K Osafune, L Davidow, K Lam, ... Nature chemical biology 5 (4), 258-265, 2009 | 614 | 2009 |
| Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells M Borowiak, R Maehr, S Chen, AE Chen, W Tang, JL Fox, SL Schreiber, ... Cell stem cell 4 (4), 348-358, 2009 | 536 | 2009 |
| Ultrastructural details of mammalian chromosome architecture N Krietenstein, S Abraham, SV Venev, N Abdennur, J Gibcus, THS Hsieh, ... Molecular cell 78 (3), 554-565. e7, 2020 | 428 | 2020 |
| SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation TF Westbrook, G Hu, XL Ang, P Mulligan, NN Pavlova, A Liang, Y Leng, ... Nature 452 (7185), 370-374, 2008 | 363 | 2008 |
| Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells NA Kearns, RMJ Genga, MS Enuameh, M Garber, SA Wolfe, R Maehr Development 141 (1), 219-223, 2014 | 358 | 2014 |
| Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal KK Niakan, H Ji, R Maehr, SA Vokes, KT Rodolfa, RI Sherwood, ... Genes & development 24 (3), 312-326, 2010 | 333 | 2010 |
| Differential dependence of CD4+ CD25+ regulatory and natural killer-like T cells on signals leading to NF-κB activation M Schmidt-Supprian, J Tian, EP Grant, M Pasparakis, R Maehr, H Ovaa, ... Proceedings of the National Academy of Sciences 101 (13), 4566-4571, 2004 | 285 | 2004 |
| Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes JAB Babon, ME DeNicola, DM Blodgett, I Crèvecoeur, TS Buttrick, ... Nature medicine 22 (12), 1482-1487, 2016 | 283 | 2016 |
| Analysis of protease activity in live antigen-presenting cells shows regulation of the phagosomal proteolytic contents during dendritic cell activation AM Lennon-Duménil, AH Bakker, R Maehr, E Fiebiger, HS Overkleeft, ... The Journal of experimental medicine 196 (4), 529-540, 2002 | 276 | 2002 |
| The mouse polyubiquitin gene UbC is essential for fetal liver development, cell‐cycle progression and stress tolerance KY Ryu, R Maehr, CA Gilchrist, MA Long, DM Bouley, B Mueller, ... The EMBO journal 26 (11), 2693-2706, 2007 | 190 | 2007 |
| De novo formation of insulin-producing “neo-β cell islets” from intestinal crypts YJ Chen, SR Finkbeiner, D Weinblatt, MJ Emmett, F Tameire, M Yousefi, ... Cell reports 6 (6), 1046-1058, 2014 | 183 | 2014 |
| A single-cell transcriptomic atlas of thymus organogenesis resolves cell types and developmental maturation EM Kernfeld, RMJ Genga, K Neherin, ME Magaletta, P Xu, R Maehr Immunity 48 (6), 1258-1270. e6, 2018 | 161 | 2018 |
| Wnt signaling specifies and patterns intestinal endoderm RI Sherwood, R Maehr, EO Mazzoni, DA Melton Mechanisms of development 128 (7-10), 387-400, 2011 | 148 | 2011 |
| SARS-CoV-2 initiates programmed cell death in platelets M Koupenova, HA Corkrey, O Vitseva, K Tanriverdi, M Somasundaran, ... Circulation research 129 (6), 631-646, 2021 | 147 | 2021 |
| Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway B Blum, AN Roose, O Barrandon, R Maehr, AC Arvanites, LS Davidow, ... Elife 3, e02809, 2014 | 136 | 2014 |
