Genetic effects on gene expression across human tissues GTEx Consortium Lead analysts: Aguet François 1 Brown Andrew A. 2 3 4 Castel ... Nature 550 (7675), 204-213, 2017 | 3331 | 2017 |
The GTEx Consortium atlas of genetic regulatory effects across human tissues GTEx Consortium Science 369 (6509), 1318-1330, 2020 | 2586 | 2020 |
Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions RE Johnson, MT Washington, L Haracska, S Prakash, L Prakash Nature 406 (6799), 1015-1019, 2000 | 813 | 2000 |
Fidelity of human DNA polymerase η RE Johnson, MT Washington, S Prakash, L Prakash Journal of Biological Chemistry 275 (11), 7447-7450, 2000 | 525 | 2000 |
The many roles of PCNA in eukaryotic DNA replication EM Boehm, MS Gildenberg, MT Washington The Enzymes 39, 231-254, 2016 | 314 | 2016 |
A quantitative proteome map of the human body L Jiang, M Wang, S Lin, R Jian, X Li, J Chan, G Dong, H Fang, ... Cell 183 (1), 269-283. e19, 2020 | 297 | 2020 |
Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase η MT Washington, RE Johnson, S Prakash, L Prakash Journal of Biological Chemistry 274 (52), 36835-36838, 1999 | 236 | 1999 |
Accuracy of thymine–thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase η MT Washington, RE Johnson, S Prakash, L Prakash Proceedings of the National Academy of Sciences 97 (7), 3094-3099, 2000 | 232 | 2000 |
Human DINB1-encoded DNA polymerase κ is a promiscuous extender of mispaired primer termini MT Washington, RE Johnson, L Prakash, S Prakash Proceedings of the National Academy of Sciences 99 (4), 1910-1914, 2002 | 215 | 2002 |
Bridging the gap: a family of novel DNA polymerases that replicate faulty DNA RE Johnson, MT Washington, S Prakash, L Prakash Proceedings of the National Academy of Sciences 96 (22), 12224-12226, 1999 | 176 | 1999 |
Co-expression networks reveal the tissue-specific regulation of transcription and splicing A Saha, Y Kim, ADH Gewirtz, B Jo, C Gao, IC McDowell, BE Engelhardt, ... Genome research 27 (11), 1843-1858, 2017 | 168 | 2017 |
Yeast DNA polymerase η utilizes an induced-fit mechanism of nucleotide incorporation MT Washington, L Prakash, S Prakash Cell 107 (7), 917-927, 2001 | 168 | 2001 |
Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases ι and κ MT Washington, IG Minko, RE Johnson, WT Wolfle, TM Harris, RS Lloyd, ... Molecular and cellular biology, 2004 | 143 | 2004 |
Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease Nature genetics 49 (12), 1664-1670, 2017 | 139 | 2017 |
Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange BD Freudenthal, L Gakhar, S Ramaswamy, MT Washington Nature structural & molecular biology 17 (4), 479-484, 2010 | 138 | 2010 |
Inefficient bypass of an abasic site by DNA polymerase η L Haracska, MT Washington, S Prakash, L Prakash Journal of Biological Chemistry 276 (9), 6861-6866, 2001 | 138 | 2001 |
PCNA structure and function: insights from structures of PCNA complexes and post-translationally modified PCNA LM Dieckman, BD Freudenthal, MT Washington The eukaryotic replisome: a guide to protein structure and function, 281-299, 2012 | 127 | 2012 |
Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase ζ MT Washington, IG Minko, RE Johnson, L Haracska, TM Harris, RS Lloyd, ... Molecular and cellular biology, 2004 | 126 | 2004 |
Biochemical analysis of mutant T7 primase/helicase proteins defective in DNA binding, nucleotide hydrolysis, and the coupling of hydrolysis with DNA unwinding MT Washington, AH Rosenberg, K Griffin, FW Studier, SS Patel Journal of Biological Chemistry 271 (43), 26825-26834, 1996 | 124 | 1996 |
The dTTPase mechanism of T7 DNA helicase resembles the binding change mechanism of the F1-ATPase MM Hingorani, MT Washington, KC Moore, SS Patel Proceedings of the National Academy of Sciences 94 (10), 5012-5017, 1997 | 118 | 1997 |