CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter SR Choudhury, Y Cui, K Lubecka, B Stefanska, J Irudayaraj Oncotarget 7 (29), 46545, 2016 | 394 | 2016 |
The role of lipid droplets and adipocytes in cancer. Raman imaging of cell cultures: MCF10A, MCF7, and MDA-MB-231 compared to adipocytes in cancerous human breast tissue H Abramczyk, J Surmacki, M Kopeć, AK Olejnik, ... Analyst 140 (7), 2224-2235, 2015 | 223 | 2015 |
Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity K Lubecka, L Kurzava, K Flower, H Buvala, H Zhang, D Teegarden, ... Carcinogenesis 37 (7), 656-668, 2016 | 96 | 2016 |
The role of sulforaphane in epigenetic mechanisms, including interdependence between histone modification and DNA methylation A Kaufman-Szymczyk, G Majewski, K Lubecka-Pietruszewska, ... International journal of molecular sciences 16 (12), 29732-29743, 2015 | 95 | 2015 |
Dietary antioxidants remodel DNA methylation patterns in chronic disease M Beetch, S Harandi‐Zadeh, K Shen, K Lubecka, DD Kitts, HM O'Hagan, ... British journal of pharmacology 177 (6), 1382-1408, 2020 | 68 | 2020 |
Sulforaphane alone and in combination with clofarabine epigenetically regulates the expression of DNA methylation-silenced tumour suppressor genes in human breast cancer cells K Lubecka-Pietruszewska, A Kaufman-Szymczyk, B Stefanska, ... Journal of Nutrigenetics and Nutrigenomics 8 (2), 91-101, 2015 | 67 | 2015 |
Folic acid enforces DNA methylation-mediated transcriptional silencing of PTEN, APC and RARbeta2 tumour suppressor genes in breast cancer K Lubecka-Pietruszewska, A Kaufman-Szymczyk, B Stefanska, ... Biochemical and biophysical research communications 430 (2), 623-628, 2013 | 67 | 2013 |
Curcumin from turmeric rhizome: A potential modulator of DNA methylation machinery in breast cancer inhibition K Fabianowska-Majewska, A Kaufman-Szymczyk, A Szymanska-Kolba, ... Nutrients 13 (2), 332, 2021 | 50 | 2021 |
Clofarabine, a novel adenosine analogue, reactivates DNA methylation-silenced tumour suppressor genes and inhibits cell growth in breast cancer cells K Lubecka-Pietruszewska, A Kaufman-Szymczyk, B Stefanska, ... European Journal of Pharmacology 723, 276-287, 2014 | 31 | 2014 |
Novel clofarabine-based combinations with polyphenols epigenetically reactivate retinoic acid receptor beta, inhibit cell growth, and induce apoptosis of breast cancer cells K Lubecka, A Kaufman-Szymczyk, B Cebula-Obrzut, P Smolewski, ... International journal of molecular sciences 19 (12), 3970, 2018 | 25 | 2018 |
Stilbenoid‐mediated epigenetic activation of semaphorin 3A in breast cancer cells involves changes in dynamic interactions of DNA with DNMT3A and NF1C transcription factor M Beetch, K Lubecka, K Shen, K Flower, S Harandi‐Zadeh, M Suderman, ... Molecular nutrition & food research 63 (19), 1801386, 2019 | 23 | 2019 |
Inhibition of breast cancer cell growth by the combination of clofarabine and sulforaphane involves epigenetically mediated CDKN2A upregulation K Lubecka, A Kaufman-Szymczyk, K Fabianowska-Majewska Nucleosides, Nucleotides and Nucleic Acids 37 (5), 280-289, 2018 | 19 | 2018 |
Loci-specific differences in blood DNA methylation in HBV-negative populations at risk for hepatocellular carcinoma development K Lubecka, K Flower, M Beetch, J Qiu, L Kurzava, H Buvala, A Ruhayel, ... Epigenetics 13 (6), 605-626, 2018 | 16 | 2018 |
Clofarabine (2-chloro-2′-fluoro-2′-deoxyarabinosyladenine)–biochemical aspects of anticancer activity K Majda, K Lubecka, A Kaufman-Szymczyk, K Fabianowska-Majewska Acta Pol Pharm 68 (4), 459-66, 2011 | 15 | 2011 |
Pterostilbene leads to DNMT3B-mediated DNA methylation and silencing of OCT1-targeted oncogenes in breast cancer cells M Beetch, C Boycott, S Harandi-Zadeh, T Yang, BJE Martin, ... The Journal of nutritional biochemistry 98, 108815, 2021 | 14 | 2021 |
Clofarabine‑phytochemical combination exposures in CML cells inhibit DNA methylation machinery, upregulate tumor suppressor genes and promote caspase‑dependent apoptosis A KAuFMAN‑SzyMCzyK, K Majda, A SzułAwSKA‑MRoCzEK, ... Molecular Medicine Reports 20 (4), 3597-3608, 2019 | 12 | 2019 |
Influence of clofarabine on transcriptional activity of PTEN, APC, RARB2, ZAP70 genes in K562 cells K Majda, A Kaufman-Szymczyk, K Lubecka-Pietruszewska, A Bednarek, ... Anticancer research 30 (11), 4601-4606, 2010 | 12 | 2010 |
Subtle alterations in DNA methylation patterns in normal cells in response to dietary stilbenoids M Beetch, K Lubecka, H Kristofzski, M Suderman, B Stefanska Molecular nutrition & food research 62 (14), 1800193, 2018 | 11 | 2018 |
Anticarcinogenic capabilities of plant polyphenols: Flavonoids and stilbene G Majewski, K Lubecka-Pietruszewska, A Kaufman-Szymczak, ... Pol. J. Public Health 122 (4), 434-439, 2012 | 11 | 2012 |
Epigenetic aberrations of gene expression in a rat model of hepatocellular carcinoma C Boycott, M Beetch, T Yang, K Lubecka, Y Ma, J Zhang, ... Epigenetics 17 (11), 1513-1534, 2022 | 9 | 2022 |