| Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm M Cerrone, J Montnach, X Lin, YT Zhao, M Zhang, E Agullo-Pascual, ... Nature communications 8 (1), 106, 2017 | 201 | 2017 |
| Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy JD Roberts, NP Murphy, RM Hamilton, ER Lubbers, CA James, CF Kline, ... The Journal of Clinical Investigation 129 (8), 3171-3184, 2019 | 53 | 2019 |
| Potential new mechanisms of pro-arrhythmia in arrhythmogenic cardiomyopathy: focus on calcium sensitive pathways CJM Van Opbergen, M Delmar, TAB Van Veen Netherlands Heart Journal 25, 157-169, 2017 | 52 | 2017 |
| Gelatin microspheres as vehicle for cardiac progenitor cells delivery to the myocardium DAM Feyen, R Gaetani, J Deddens, D van Keulen, C van Opbergen, ... Advanced healthcare materials 5 (9), 1071-1079, 2016 | 51 | 2016 |
| Optogenetic sensors in the zebrafish heart: a novel in vivo electrophysiological tool to study cardiac arrhythmogenesis CJM van Opbergen, CD Koopman, BJM Kok, T Knöpfel, SL Renninger, ... Theranostics 8 (17), 4750, 2018 | 50 | 2018 |
| Plakophilin-2 haploinsufficiency causes calcium handling deficits and modulates the cardiac response towards stress CJM van Opbergen, M Noorman, A Pfenniger, JS Copier, SH Vermij, Z Li, ... International journal of molecular sciences 20 (17), 4076, 2019 | 41 | 2019 |
| Mitochondrial dysfunction as substrate for arrhythmogenic cardiomyopathy: a search for new disease mechanisms CJM Van Opbergen, L Den Braven, M Delmar, TAB Van Veen Frontiers in physiology 10, 1496, 2019 | 37 | 2019 |
| Cardiac Ca2+ signalling in zebrafish: Translation of findings to man CJM van Opbergen, SM van der Voorn, MA Vos, TP de Boer, ... Progress in biophysics and molecular biology 138, 45-58, 2018 | 37 | 2018 |
| Role of plakophilin-2 expression on exercise-related progression of arrhythmogenic right ventricular cardiomyopathy: a translational study M Cerrone, GM Marron-Linares, CJM Van Opbergen, S Costa, M Bourfiss, ... European heart journal 43 (12), 1251-1264, 2022 | 31 | 2022 |
| Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2–Deficient Hearts CJM Van Opbergen, N Bagwan, SR Maurya, JC Kim, AN Smith, ... Circulation 145 (19), 1480-1496, 2022 | 28 | 2022 |
| Loss of nuclear envelope integrity and increased oxidant production cause DNA damage in adult hearts deficient in PKP2: a molecular substrate of ARVC M Pérez-Hernández, CJM van Opbergen, N Bagwan, CR Vissing, ... Circulation 146 (11), 851-867, 2022 | 25 | 2022 |
| Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model of phospholamban R14del cardiomyopathy SM Kamel, CJM van Opbergen, CD Koopman, AO Verkerk, BJD Boukens, ... Nature communications 12 (1), 7151, 2021 | 22 | 2021 |
| Transcriptomic coupling of PKP2 with inflammatory and immune pathways endogenous to adult cardiac myocytes M Pérez-Hernández, GM Marrón-Liñares, F Schlamp, A Heguy, ... Frontiers in physiology 11, 623190, 2021 | 20 | 2021 |
| The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes MS Nielsen, CJM van Opbergen, TAB van Veen, M Delmar Physiological Reviews 103 (3), 2271-2319, 2023 | 19 | 2023 |
| Blockade of the adenosine 2A receptor mitigates the cardiomyopathy induced by loss of plakophilin-2 expression M Cerrone, CJM Van Opbergen, K Malkani, N Irrera, M Zhang, ... Frontiers in Physiology 9, 1750, 2018 | 13 | 2018 |
| AAV-mediated delivery of Plakophilin-2a arrests progression of arrhythmogenic right ventricular cardiomyopathy in murine hearts: preclinical evidence supporting gene therapy in … CJM van Opbergen, B Narayanan, CB Sacramento, KM Stiles, V Mishra, ... Circulation: Genomic and Precision Medicine 17 (1), e004305, 2024 | 9 | 2024 |
| In silico Identification of Disrupted Myocardial Calcium Homeostasis as Proarrhythmic Trigger in Arrhythmogenic Cardiomyopathy A Lyon, CJM Van Opbergen, M Delmar, J Heijman, TAB Van Veen Frontiers in physiology 12, 732573, 2021 | 6 | 2021 |
| “Orphan” connexin43 in plakophilin-2 deficient hearts revealed by volume electron microscopy CJM van Opbergen, J Sall, C Petzold, K Dancel-Manning, M Delmar, ... Frontiers in Cell and Developmental Biology 10, 843687, 2022 | 5 | 2022 |
| Nanogold based protein localization enables subcellular visualization of cell junction protein by SBF-SEM FX Liang, J Sall, C Petzold, CJM van Opbergen, X Liang, M Delmar Methods in cell biology 177, 55-81, 2023 | 2 | 2023 |
| Leaky RyR2 channels as pro-arrhythmic trigger in the PKP2-deficient atrial myocardium CJM Van Opbergen, K Phadke, X Lin, M Zhang, A Lundby, M Cerrone, ... Cardiovascular Research 120 (Supplement_1), cvae088. 099, 2024 | | 2024 |
