| Structural basis for partial agonist action at ionotropic glutamate receptors R Jin, TG Banke, ML Mayer, SF Traynelis, E Gouaux Nature neuroscience 6 (8), 803-810, 2003 | 455 | 2003 |
| Massively parallel de novo protein design for targeted therapeutics A Chevalier, DA Silva, GJ Rocklin, DR Hicks, R Vergara, P Murapa, ... Nature 550 (7674), 74-79, 2017 | 453 | 2017 |
| Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity R Jin, A Rummel, T Binz, AT Brunger Nature 444 (7122), 1092-1095, 2006 | 278 | 2006 |
| Mechanism of positive allosteric modulators acting on AMPA receptors R Jin, S Clark, AM Weeks, JT Dudman, E Gouaux, KM Partin Journal of Neuroscience 25 (39), 9027-9036, 2005 | 276 | 2005 |
| Botulinum neurotoxin is shielded by NTNHA in an interlocked complex S Gu, S Rumpel, J Zhou, J Strotmeier, H Bigalke, K Perry, CB Shoemaker, ... Science 335 (6071), 977-981, 2012 | 248 | 2012 |
| Crystal structure and association behaviour of the GluR2 amino‐terminal domain R Jin, SK Singh, S Gu, H Furukawa, AI Sobolevsky, J Zhou, Y Jin, ... The EMBO journal 28 (12), 1812-1823, 2009 | 204 | 2009 |
| Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core A Hogner, JS Kastrup, R Jin, T Liljefors, ML Mayer, J Egebjerg, IK Larsen, ... Journal of molecular biology 322 (1), 93-109, 2002 | 202 | 2002 |
| Structural basis of agrin–LRP4–MuSK signaling Y Zong, B Zhang, S Gu, K Lee, J Zhou, G Yao, D Figueiredo, K Perry, ... Genes & development 26 (3), 247-258, 2012 | 189 | 2012 |
| Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase R Jin, JR Junutula, HT Matern, KE Ervin, RH Scheller, AT Brunger The EMBO journal 24 (12), 2064-2074, 2005 | 178 | 2005 |
| Mechanism of Activation and Selectivity in a Ligand-Gated Ion Channel: Structural and Functional Studies of GluR2 and Quisqualate, R Jin, M Horning, ML Mayer, E Gouaux Biochemistry 41 (52), 15635-15643, 2002 | 142 | 2002 |
| Structure of a bimodular botulinum neurotoxin complex provides insights into its oral toxicity K Lee, S Gu, L Jin, TTN Le, LW Cheng, J Strotmeier, AM Kruel, G Yao, ... PLoS pathogens 9 (10), e1003690, 2013 | 137 | 2013 |
| The N-terminal domain of GluR6-subtype glutamate receptor ion channels J Kumar, P Schuck, R Jin, ML Mayer Nature structural & molecular biology 16 (6), 631-638, 2009 | 135 | 2009 |
| Botulinum neurotoxin heavy chain belt as an intramolecular chaperone for the light chain AT Brunger, MA Breidenbach, R Jin, A Fischer, JS Santos, M Montal PLoS pathogens 3 (9), e113, 2007 | 130 | 2007 |
| Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B P Chen, L Tao, T Wang, J Zhang, A He, K Lam, Z Liu, X He, K Perry, ... Science 360 (6389), 664-669, 2018 | 126 | 2018 |
| Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex K Lee, X Zhong, S Gu, AM Kruel, MB Dorner, K Perry, A Rummel, M Dong, ... Science 344 (6190), 1405-1410, 2014 | 125 | 2014 |
| N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A G Yao, S Zhang, S Mahrhold, K Lam, D Stern, K Bagramyan, K Perry, ... Nature structural & molecular biology 23 (7), 656-662, 2016 | 123 | 2016 |
| Probing the ligand binding domain of the GluR2 receptor by proteolysis and deletion mutagenesis defines domain boundaries and yields a crystallizable construct GQ Chen, YU Sun, R Jin, E Gouaux Protein Science 7 (12), 2623-2630, 1998 | 114 | 1998 |
| Structural mechanisms of the agrin–LRP4–MuSK signaling pathway in neuromuscular junction differentiation Y Zong, R Jin Cellular and Molecular Life Sciences 70, 3077-3088, 2013 | 95 | 2013 |
| Assembly and function of the botulinum neurotoxin progenitor complex S Gu, R Jin Botulinum Neurotoxins, 21-44, 2013 | 95 | 2013 |
| Probing the function, conformational plasticity, and dimer− dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal R Jin, E Gouaux Biochemistry 42 (18), 5201-5213, 2003 | 92 | 2003 |
