Cellular stress and apoptosis contribute to the pathogenesis of autism spectrum disorder D Dong, HR Zielke, D Yeh, P Yang Autism Research 11 (7), 1076-1090, 2018 | 104 | 2018 |
Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress, and apoptosis Y Wu, EA Reece, J Zhong, D Dong, WB Shen, CR Harman, P Yang American journal of obstetrics and gynecology 215 (3), 366. e1-366. e10, 2016 | 95 | 2016 |
Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancy F Wang, C Xu, EA Reece, X Li, Y Wu, C Harman, J Yu, D Dong, C Wang, ... Nature communications 8 (1), 15182, 2017 | 91 | 2017 |
Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways Q Sun, W Zhong, W Zhang, Q Li, X Sun, X Tan, X Sun, D Dong, Z Zhou American Journal of Physiology-Gastrointestinal and Liver Physiology 308 (9 …, 2015 | 85 | 2015 |
The miR-322-TRAF3 circuit mediates the pro-apoptotic effect of high glucose on neural stem cells H Gu, J Yu, D Dong, Q Zhou, JY Wang, P Yang Toxicological Sciences 144 (1), 186-196, 2015 | 65 | 2015 |
High glucose inhibits neural stem cell differentiation through oxidative stress and endoplasmic reticulum stress X Chen, WB Shen, P Yang, D Dong, W Sun, P Yang Stem cells and development 27 (11), 745-755, 2018 | 59 | 2018 |
MiR-17 downregulation by high glucose stabilizes thioredoxin-interacting protein and removes thioredoxin inhibition on ASK1 leading to apoptosis D Dong, N Fu, P Yang Toxicological Sciences 150 (1), 84-96, 2016 | 59 | 2016 |
New development of the yolk sac theory in diabetic embryopathy: molecular mechanism and link to structural birth defects D Dong, EA Reece, X Lin, Y Wu, N AriasVillela, P Yang American journal of obstetrics and gynecology 214 (2), 192-202, 2016 | 56 | 2016 |
Robust genome editing in adult vascular endothelium by nanoparticle delivery of CRISPR-Cas9 plasmid DNA X Zhang, H Jin, X Huang, B Chaurasiya, D Dong, TP Shanley, YY Zhao Cell reports 38 (1), 2022 | 54 | 2022 |
Endoplasmic reticulum stress-induced CHOP inhibits PGC-1α and causes mitochondrial dysfunction in diabetic embryopathy X Chen, J Zhong, D Dong, G Liu, P Yang Toxicological Sciences 158 (2), 275-285, 2017 | 46 | 2017 |
Disturbance of copper homeostasis is a mechanism for homocysteine-induced vascular endothelial cell injury D Dong, B Wang, W Yin, X Ding, J Yu, YJ Kang PLoS One 8 (10), e76209, 2013 | 45 | 2013 |
Oxidative stress-induced miR-27a targets the redox gene nuclear factor erythroid 2-related factor 2 in diabetic embryopathy Y Zhao, D Dong, EA Reece, AR Wang, P Yang American journal of obstetrics and gynecology 218 (1), 136. e1-136. e10, 2018 | 44 | 2018 |
High glucose–repressed CITED2 expression through miR-200b triggers the unfolded protein response and endoplasmic reticulum stress H Gu, J Yu, D Dong, Q Zhou, JY Wang, S Fang, P Yang Diabetes 65 (1), 149-163, 2016 | 40 | 2016 |
Maternal diabetes triggers DNA damage and DNA damage response in neurulation stage embryos through oxidative stress D Dong, J Yu, Y Wu, N Fu, NA Villela, P Yang Biochemical and biophysical research communications 467 (2), 407-412, 2015 | 36 | 2015 |
microRNA expression profiling and functional annotation analysis of their targets modulated by oxidative stress during embryonic heart development in diabetic mice D Dong, Y Zhang, EA Reece, L Wang, CR Harman, P Yang Reproductive toxicology 65, 365-374, 2016 | 33 | 2016 |
Oxidative products from alcohol metabolism differentially modulate pro-inflammatory cytokine expression in Kupffer cells and hepatocytes D Dong, W Zhong, Q Sun, W Zhang, X Sun, Z Zhou Cytokine 85, 109-119, 2016 | 23 | 2016 |
Cytochrome c oxidase is essential for copper-induced regression of cardiomyocyte hypertrophy X Zuo, H Xie, D Dong, N Jiang, H Zhu, YJ Kang Cardiovascular toxicology 10, 208-215, 2010 | 23 | 2010 |
The Nrf2 activator vinylsulfone reduces high glucose-induced neural tube defects by suppressing cellular stress and apoptosis D Dong, EA Reece, P Yang Reproductive sciences 23 (8), 993-1000, 2016 | 21 | 2016 |
Homocysteine restricts copper availability leading to suppression of cytochrome C oxidase activity in phenylephrine-treated cardiomyocytes X Zuo, D Dong, M Sun, H Xie, YJ Kang PLoS One 8 (6), e67549, 2013 | 19 | 2013 |
Endothelial PHD2 deficiency induces nitrative stress via suppression of caveolin-1 in pulmonary hypertension B Liu, Y Peng, D Yi, N Machireddy, D Dong, K Ramirez, J Dai, ... European Respiratory Journal 60 (6), 2022 | 18 | 2022 |