Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves JA Gomez-Sanchez, L Carty, M Iruarrizaga-Lejarreta, M Palomo-Irigoyen, ... Journal of Cell Biology 210 (1), 153-168, 2015 | 412 | 2015 |
After nerve injury, lineage tracing shows that myelin and Remak Schwann cells elongate extensively and branch to form repair Schwann cells, which shorten radically on remyelination JA Gomez-Sanchez, KS Pilch, M van der Lans, SV Fazal, C Benito, ... Journal of Neuroscience 37 (37), 9086-9099, 2017 | 239 | 2017 |
Changes in the coding and non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury PJ Arthur-Farraj, CC Morgan, M Adamowicz, JA Gomez-Sanchez, ... Cell reports 20 (11), 2719-2734, 2017 | 176 | 2017 |
STAT3 controls the long-term survival and phenotype of repair Schwann cells during nerve regeneration C Benito, CM Davis, JA Gomez-Sanchez, M Turmaine, D Meijer, V Poli, ... Journal of Neuroscience 37 (16), 4255-4269, 2017 | 118 | 2017 |
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun LJ Wagstaff, JA Gomez-Sanchez, SV Fazal, GW Otto, AM Kilpatrick, ... Elife 10, e62232, 2021 | 89 | 2021 |
Graded elevation of c-Jun in Schwann cells in vivo: gene dosage determines effects on development, remyelination, tumorigenesis, and hypomyelination SV Fazal, JA Gomez-Sanchez, LJ Wagstaff, N Musner, G Otto, M Janz, ... Journal of Neuroscience 37 (50), 12297-12313, 2017 | 84 | 2017 |
Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell overproliferation during nerve regeneration and after tumorigenic challenge JA Gomez-Sanchez, C Gomis-Coloma, C Morenilla-Palao, G Peiro, ... Brain 136 (7), 2262-2278, 2013 | 67 | 2013 |
Role of the excitability brake potassium current IKD in cold allodynia induced by chronic peripheral nerve injury A González, G Ugarte, C Restrepo, G Herrera, R Piña, ... Journal of Neuroscience 37 (12), 3109-3126, 2017 | 46 | 2017 |
Sustained axon–glial signaling induces Schwann cell hyperproliferation, remak bundle myelination, and tumorigenesis JA Gomez-Sanchez, ML de Armentia, R Lujan, N Kessaris, ... Journal of Neuroscience 29 (36), 11304-11315, 2009 | 42 | 2009 |
L1CAM binds ErbB receptors through Ig-like domains coupling cell adhesion and neuregulin signalling E Donier, JA Gomez-Sanchez, C Grijota-Martinez, J Lakoma, S Baars, ... PloS one 7 (7), e40674, 2012 | 35 | 2012 |
Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells C Gomis-Coloma, S Velasco-Aviles, JA Gomez-Sanchez, A Casillas-Bajo, ... Journal of Cell Biology 217 (4), 1249-1268, 2018 | 30 | 2018 |
Emerging role of HDACs in regeneration and ageing in the peripheral nervous system: repair Schwann cells as pivotal targets JA Gomez-Sanchez, N Patel, F Martirena, SV Fazal, C Mutschler, ... International Journal of Molecular Sciences 23 (6), 2996, 2022 | 17 | 2022 |
Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration following peripheral nerve injury A Fuentes‐Flores, C Geronimo‐Olvera, K Girardi, D Necuñir‐Ibarra, ... EMBO Molecular Medicine 15 (12), e17907, 2023 | 10 | 2023 |
Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration VK Sundaram, V Schütza, NH Schröter, A Backhaus, A Bilsing, L Joneck, ... Cell Metabolism 35 (12), 2136-2152. e9, 2023 | 10 | 2023 |
An Experimental Model of Neuro–Immune Interactions in the Eye: Corneal Sensory Nerves and Resident Dendritic Cells L Frutos-Rincón, JA Gómez-Sánchez, A Íñigo-Portugués, MC Acosta, ... International Journal of Molecular Sciences 23 (6), 2997, 2022 | 10 | 2022 |
A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair S Velasco-Aviles, N Patel, A Casillas-Bajo, L Frutos-Rincón, E Velasco, ... Elife 11, 2022 | 8 | 2022 |
The relationship between Schwann cell c-Jun and regeneration failures due to ageing and long-term injury LJ Wagstaff, JA Gomez-Sanchez, R Mirsky, KR Jessen 13th European Meeting on Glial Cells in Health and Disease, 2017 | 8 | 2017 |
SARM1 detection in myelinating glia: sarm1/Sarm1 is dispensable for PNS and CNS myelination in zebrafish and mice SV Fazal, C Mutschler, CZ Chen, M Turmaine, CY Chen, YP Hsueh, ... Frontiers in Cellular Neuroscience 17, 1158388, 2023 | 6 | 2023 |
Glial cell alterations in diabetes-induced neurodegeneration M Llorián-Salvador, S Cabeza-Fernández, JA Gomez-Sanchez, ... Cellular and Molecular Life Sciences 81 (1), 47, 2024 | 5 | 2024 |
Schwann Cells as Orchestrators of Nerve Repair: Implications for Tissue Regeneration and Pathologies RM Stassart, JA Gomez-Sanchez, AC Lloyd Cold Spring Harbor Perspectives in Biology 16 (6), a041363, 2024 | 4 | 2024 |