Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13281* | 2021 |
Unraveling the mysteries of serum albumin—more than just a serum protein AM Merlot, DS Kalinowski, DR Richardson Frontiers in physiology 5, 108587, 2014 | 662 | 2014 |
Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease DJR Lane, AM Merlot, MLH Huang, DH Bae, PJ Jansson, S Sahni, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (5), 1130-1144, 2015 | 384 | 2015 |
Clinical development of targeted and immune based anti-cancer therapies NA Seebacher, AE Stacy, GM Porter, AM Merlot Journal of Experimental & Clinical Cancer Research 38 (1), 156, 2019 | 241 | 2019 |
Roads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signaling J Paluncic, Z Kovacevic, PJ Jansson, D Kalinowski, AM Merlot, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (4), 770-784, 2016 | 227 | 2016 |
Novel chelators for cancer treatment: where are we now? AM Merlot, DS Kalinowski, DR Richardson Antioxidants & redox signaling 18 (8), 973-1006, 2013 | 217 | 2013 |
Targeting cancer by binding iron: Dissecting cellular signaling pathways GYL Lui, Z Kovacevic, V Richardson, AM Merlot, DS Kalinowski, ... Oncotarget 6 (22), 18748, 2015 | 162 | 2015 |
The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the “Triad of Death” in cancer by Di-2-pyridylketone thiosemicarbazones PJ Jansson, DS Kalinowski, DJR Lane, Z Kovacevic, NA Seebacher, ... Pharmacological research 100, 255-260, 2015 | 157 | 2015 |
Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics DS Kalinowski, C Stefani, S Toyokuni, T Ganz, GJ Anderson, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (4), 727-748, 2016 | 143 | 2016 |
Duodenal Cytochrome b (DCYTB) in Iron Metabolism: An Update on Function and Regulation DJR Lane, DH Bae, AM Merlot, S Sahni, DR Richardson Nutrients 7 (4), 2274-2296, 2015 | 141 | 2015 |
Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial–mesenchymal transition DJR Lane, TM Mills, NH Shafie, AM Merlot, RS Moussa, DS Kalinowski, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1845 (2), 166-181, 2014 | 111 | 2014 |
Synthesis and characterization of quinoline-based thiosemicarbazones and correlation of cellular iron-binding efficacy to anti-tumor efficacy M Serda, DS Kalinowski, A Mrozek-Wilczkiewicz, R Musiol, A Szurko, ... Bioorganic & medicinal chemistry letters 22 (17), 5527-5531, 2012 | 85 | 2012 |
Gene of the month: BECN1 S Sahni, AM Merlot, S Krishan, PJ Jansson, DR Richardson Journal of Clinical Pathology 67 (8), 656-660, 2014 | 80 | 2014 |
The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1 W Liu, F Yue, M Zheng, A Merlot, DH Bae, M Huang, D Lane, P Jansson, ... Oncotarget 6 (11), 8851, 2015 | 72 | 2015 |
The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targets W Liu, Z Kovacevic, Z Peng, R Jin, P Wang, F Yue, M Zheng, MLH Huang, ... Oncotarget 6 (34), 35522, 2015 | 67 | 2015 |
Frataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxia S Chiang, Z Kovacevic, S Sahni, DJR Lane, AM Merlot, DS Kalinowski, ... Clinical science 130 (11), 853-870, 2016 | 65 | 2016 |
Lysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4, 4-dimethyl-3-thiosemicarbazone (Dp44mT) EM Gutierrez, NA Seebacher, L Arzuman, Z Kovacevic, DJR Lane, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1665-1681, 2016 | 48 | 2016 |
Novel thiosemicarbazones regulate the signal transducer and activator of transcription 3 (STAT3) pathway: Inhibition of constitutive and interleukin 6–induced activation by … GYL Lui, Z Kovacevic, SV Menezes, DS Kalinowski, AM Merlot, S Sahni, ... Molecular pharmacology 87 (3), 543-560, 2015 | 45 | 2015 |
Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4, 4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α … AM Merlot, NH Shafie, Y Yu, V Richardson, PJ Jansson, S Sahni, ... Biochemical Pharmacology 109, 27-47, 2016 | 40 | 2016 |
Potentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells AM Merlot, S Sahni, DJR Lane, AM Fordham, N Pantarat, DE Hibbs, ... Oncotarget 6 (12), 10374, 2015 | 36 | 2015 |