Microbiota regulates immune defense against respiratory tract influenza A virus infection T Ichinohe, IK Pang, Y Kumamoto, DR Peaper, JH Ho, TS Murray, ... Proceedings of the National Academy of Sciences 108 (13), 5354-5359, 2011 | 1637 | 2011 |
Inflammasome recognition of influenza virus is essential for adaptive immune responses T Ichinohe, HK Lee, Y Ogura, R Flavell, A Iwasaki Journal of Experimental Medicine 206 (1), 79-87, 2009 | 838 | 2009 |
Influenza virus activates inflammasomes via its intracellular M2 ion channel T Ichinohe, IK Pang, A Iwasaki Nature immunology 11 (5), 404-410, 2010 | 778 | 2010 |
Severe acute respiratory syndrome coronavirus viroporin 3a activates the NLRP3 inflammasome IY Chen, M Moriyama, MF Chang, T Ichinohe Frontiers in microbiology 10, 50, 2019 | 632 | 2019 |
Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I H Hasegawa, H Sawa, MJ Lewis, Y Orba, N Sheehy, Y Yamamoto, ... Nature medicine 12 (4), 466-472, 2006 | 338 | 2006 |
Synthetic double-stranded RNA poly (I: C) combined with mucosal vaccine protects against influenza virus infection T Ichinohe, I Watanabe, S Ito, H Fujii, M Moriyama, S Tamura, ... Journal of virology 79 (5), 2910-2919, 2005 | 322 | 2005 |
Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection T Ichinohe, T Yamazaki, T Koshiba, Y Yanagi Proceedings of the National Academy of Sciences 110 (44), 17963-17968, 2013 | 305 | 2013 |
Influenza A virus protein PB1-F2 translocates into mitochondria via Tom40 channels and impairs innate immunity T Yoshizumi, T Ichinohe, O Sasaki, H Otera, S Kawabata, K Mihara, ... Nature communications 5 (1), 4713, 2014 | 250 | 2014 |
Encephalomyocarditis virus viroporin 2B activates NLRP3 inflammasome M Ito, Y Yanagi, T Ichinohe Public Library of Science 8 (8), e1002857, 2012 | 211 | 2012 |
Response of host inflammasomes to viral infection IY Chen, T Ichinohe Trends in microbiology 23 (1), 55-63, 2015 | 210 | 2015 |
Cross-protection against H5N1 influenza virus infection is afforded by intranasal inoculation with seasonal trivalent inactivated influenza vaccine T Ichinohe, S Tamura, A Kawaguchi, A Ninomiya, M Imai, S Itamura, ... The Journal of infectious diseases 196 (9), 1313-1320, 2007 | 173 | 2007 |
IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8+ T cell responses to influenza A virus IK Pang, T Ichinohe, A Iwasaki Nature immunology 14 (3), 246-253, 2013 | 172 | 2013 |
Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses M Moriyama, T Koshiba, T Ichinohe Nature communications 10 (1), 4624, 2019 | 160 | 2019 |
Herpes simplex virus 1 VP22 inhibits AIM2-dependent inflammasome activation to enable efficient viral replication Y Maruzuru, T Ichinohe, R Sato, K Miyake, T Okano, T Suzuki, T Koshiba, ... Cell host & microbe 23 (2), 254-265. e7, 2018 | 143 | 2018 |
Measles virus V protein inhibits NLRP3 inflammasome-mediated interleukin-1β secretion N Komune, T Ichinohe, M Ito, Y Yanagi Journal of virology 85 (24), 13019-13026, 2011 | 138 | 2011 |
Mechanism of NKT cell activation by intranasal coadministration of α-galactosylceramide, which can induce cross-protection against influenza viruses H Kamijuku, Y Nagata, X Jiang, T Ichinohe, T Tashiro, K Mori, ... Mucosal immunology 1 (3), 208-218, 2008 | 123 | 2008 |
Intranasal immunization with H5N1 vaccine plus Poly I: Poly C12U, a Toll-like receptor agonist, protects mice against homologous and heterologous virus challenge T Ichinohe, A Kawaguchi, S Tamura, H Takahashi, H Sawa, A Ninomiya, ... Microbes and Infection 9 (11), 1333-1340, 2007 | 120 | 2007 |
High ambient temperature dampens adaptive immune responses to influenza A virus infection M Moriyama, T Ichinohe Proceedings of the National Academy of Sciences 116 (8), 3118-3125, 2019 | 115 | 2019 |
Intranasal administration of adjuvant-combined recombinant influenza virus HA vaccine protects mice from the lethal H5N1 virus infection Y Asahi-Ozaki, S Itamura, T Ichinohe, P Strong, S Tamura, H Takahashi, ... Microbes and infection 8 (12-13), 2706-2714, 2006 | 106 | 2006 |
The RNA-and TRIM25-binding domains of influenza virus NS1 protein are essential for suppression of NLRP3 inflammasome-mediated interleukin-1β secretion M Moriyama, IY Chen, A Kawaguchi, T Koshiba, K Nagata, H Takeyama, ... Journal of virology 90 (8), 4105-4114, 2016 | 105 | 2016 |