Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling A Nakao, M Afrakhte, A Morn, T Nakayama, JL Christian, R Heuchel, ... Nature 389 (6651), 631-635, 1997 | 2399 | 1997 |
Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene S Dennler, S Itoh, D Vivien, P ten Dijke, S Huet, JM Gauthier The EMBO journal, 1998 | 2181 | 1998 |
Balancing the activation state of the endothelium via two distinct TGF‐β type I receptors MJ Goumans, G Valdimarsdottir, S Itoh, A Rosendahl, P Sideras, ... The EMBO journal, 2002 | 1486 | 2002 |
Activin receptor-like kinase (ALK) 1 is an antagonistic mediator of lateral TGFβ/ALK5 signaling MJ Goumans, G Valdimarsdottir, S Itoh, F Lebrin, J Larsson, C Mummery, ... Molecular cell 12 (4), 817-828, 2003 | 905 | 2003 |
Signaling of transforming growth factor‐β family members through Smad proteins S Itoh, F Itoh, MJ Goumans, P ten Dijke European Journal of Biochemistry 267 (24), 6954-6967, 2000 | 886 | 2000 |
Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin, and bone morphogenetic … LJC Jonk, S Itoh, CH Heldin, P ten Dijke, W Kruijer Journal of Biological Chemistry 273 (33), 21145-21152, 1998 | 704 | 1998 |
Regulation of cell proliferation by Smad proteins P Ten Dijke, MJ Goumans, F Itoh, S Itoh Journal of cellular physiology 191 (1), 1-16, 2002 | 626 | 2002 |
Negative regulation of TGF-β receptor/Smad signal transduction S Itoh, P ten Dijke Current opinion in cell biology 19 (2), 176-184, 2007 | 570 | 2007 |
Induction of inhibitory Smad6 and Smad7 mRNA by TGF-β family members M Afrakhte, A Morén, S Jossan, S Itoh, K Sampath, B Westermark, ... Biochemical and biophysical research communications 249 (2), 505-511, 1998 | 473 | 1998 |
The L45 loop in type I receptors for TGF-β family members is a critical determinant in specifying Smad isoform activation U Persson, H Izumi, S Souchelnytskyi, S Itoh, S Grimsby, U Engström, ... FEBS letters 434 (1-2), 83-87, 1998 | 470 | 1998 |
Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs H Tanimoto, S Itoh, P Ten Dijke, T Tabata Molecular cell 5 (1), 59-71, 2000 | 449 | 2000 |
Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and IRF-2 genes: implications for a gene network in the interferon system H Harada, EI Takahashi, S Itoh, K Harada, TA Hori, T Taniguchi Molecular and cellular biology 14 (2), 1500-1509, 1994 | 388 | 1994 |
Transforming growth factor β1 induces nuclear export of inhibitory Smad7 S Itoh, M Landström, A Hermansson, F Itoh, CH Heldin, NE Heldin, ... Journal of Biological Chemistry 273 (44), 29195-29201, 1998 | 381 | 1998 |
Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein–induced activation of endothelial cells G Valdimarsdottir, MJ Goumans, A Rosendahl, M Brugman, S Itoh, ... Circulation 106 (17), 2263-2270, 2002 | 375 | 2002 |
Gene structure of CYP3A4, an adult‐specific form of cytochrome P450 in human livers, and its transcriptional control H Hashimoto, K Toide, R Kitamura, M Fujita, S Tagawa, S Itoh, T Kamataki European journal of biochemistry 218 (2), 585-595, 1993 | 304 | 1993 |
Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells F Itoh, S Itoh, MJ Goumans, G Valdimarsdottir, T Iso, GP Dotto, ... The EMBO journal 23 (3), 541-551, 2004 | 282 | 2004 |
Elucidation of Smad requirement in transforming growth factor-β type I receptor-induced responses S Itoh, M Thorikay, M Kowanetz, A Moustakas, F Itoh, CH Heldin, ... Journal of Biological Chemistry 278 (6), 3751-3761, 2003 | 272 | 2003 |
Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads F Itoh, H Asao, K Sugamura, CH Heldin, P ten Dijke, S Itoh The EMBO journal, 2001 | 271 | 2001 |
TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α A Hamidi, J Song, N Thakur, S Itoh, A Marcusson, A Bergh, CH Heldin, ... Science signaling 10 (486), eaal4186, 2017 | 206 | 2017 |
TMEPAI, a transmembrane TGF-β-inducible protein, sequesters Smad proteins from active participation in TGF-β signaling Y Watanabe, S Itoh, T Goto, E Ohnishi, M Inamitsu, F Itoh, K Satoh, ... Molecular cell 37 (1), 123-134, 2010 | 200 | 2010 |