Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche F Arai, A Hirao, M Ohmura, H Sato, S Matsuoka, K Takubo, K Ito, GY Koh, ... Cell 118 (2), 149-161, 2004 | 2504 | 2004 |
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells K Ito, A Hirao, F Arai, K Takubo, S Matsuoka, K Miyamoto, M Ohmura, ... Nature medicine 12 (4), 446-451, 2006 | 1537 | 2006 |
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells K Ito, A Hirao, F Arai, S Matsuoka, K Takubo, I Hamaguchi, K Nomiyama, ... Nature 431 (7011), 997-1002, 2004 | 1362 | 2004 |
Arteriolar niches maintain haematopoietic stem cell quiescence Y Kunisaki, I Bruns, C Scheiermann, J Ahmed, S Pinho, D Zhang, ... Nature 502 (7473), 637-643, 2013 | 1273 | 2013 |
Metabolic requirements for the maintenance of self-renewing stem cells K Ito, T Suda Nature reviews Molecular cell biology 15 (4), 243-256, 2014 | 1081 | 2014 |
Foxo3a is essential for maintenance of the hematopoietic stem cell pool K Miyamoto, KY Araki, K Naka, F Arai, K Takubo, S Yamazaki, S Matsuoka, ... Cell stem cell 1 (1), 101-112, 2007 | 993 | 2007 |
A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance K Ito, A Carracedo, D Weiss, F Arai, U Ala, DE Avigan, ZT Schafer, ... Nature medicine 18 (9), 1350-1358, 2012 | 731 | 2012 |
PML targeting eradicates quiescent leukaemia-initiating cells K Ito, R Bernardi, A Morotti, S Matsuoka, G Saglio, Y Ikeda, J Rosenblatt, ... Nature 453 (7198), 1072-1078, 2008 | 698 | 2008 |
The vibrational spectra of the formate, acetate, and oxalate ions K Ito, HJ Bernstein Canadian Journal of Chemistry 34 (2), 170-178, 1956 | 683 | 1956 |
Systemic elevation of PTEN induces a tumor-suppressive metabolic state I Garcia-Cao, MS Song, RM Hobbs, G Laurent, C Giorgi, VCJ De Boer, ... Cell 149 (1), 49-62, 2012 | 435 | 2012 |
PML regulates apoptosis at endoplasmic reticulum by modulating calcium release C Giorgi, K Ito, HK Lin, C Santangelo, MR Wieckowski, M Lebiedzinska, ... Science 330 (6008), 1247-1251, 2010 | 431 | 2010 |
Salivary gland tumors in a Brazilian population: a retrospective study of 496 cases FA Ito, K Ito, PA Vargas, OP De Almeida, MA Lopes International journal of oral and maxillofacial surgery 34 (5), 533-536, 2005 | 431 | 2005 |
The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation SJ Song, K Ito, U Ala, L Kats, K Webster, SM Sun, M Jongen-Lavrencic, ... Cell stem cell 13 (1), 87-101, 2013 | 395 | 2013 |
Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by … K Ito, T Nakazato, K Yamato, Y Miyakawa, T Yamada, N Hozumi, ... Cancer research 64 (3), 1071-1078, 2004 | 355 | 2004 |
Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance K Ito, R Turcotte, J Cui, SE Zimmerman, S Pinho, T Mizoguchi, F Arai, ... Science 354 (6316), 1156-1160, 2016 | 310 | 2016 |
Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function A Papa, L Wan, M Bonora, L Salmena, MS Song, RM Hobbs, A Lunardi, ... Cell 157 (3), 595-610, 2014 | 309 | 2014 |
A metabolic prosurvival role for PML in breast cancer A Carracedo, D Weiss, AK Leliaert, M Bhasin, VCJ De Boer, G Laurent, ... The Journal of clinical investigation 122 (9), 3088-3100, 2012 | 283 | 2012 |
Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy E Laane, KP Tamm, E Buentke, K Ito, P Khahariza, J Oscarsson, ... Cell Death & Differentiation 16 (7), 1018-1029, 2009 | 244 | 2009 |
A global metagenomic map of urban microbiomes and antimicrobial resistance D Danko, D Bezdan, EE Afshin, S Ahsanuddin, C Bhattacharya, DJ Butler, ... Cell 184 (13), 3376-3393. e17, 2021 | 223 | 2021 |
Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL S Matsuoka, Y Oike, I Onoyama, A Iwama, F Arai, K Takubo, Y Mashimo, ... Genes & development 22 (8), 986-991, 2008 | 213 | 2008 |