| Supercoiling and looping promote DNA base accessibility and coordination among distant sites JM Fogg, A Judge, E Stricker, HL Chan, EL Zechiedrich Biophysical Journal 120 (3), 221a-222a, 2021 | 29 | 2021 |
| A drug-resistant β-lactamase variant changes the conformation of its active-site proton shuttle to alter substrate specificity and inhibitor potency V Soeung, S Lu, L Hu, A Judge, B Sankaran, BVV Prasad, T Palzkill Journal of Biological Chemistry 295 (52), 18239-18255, 2020 | 17 | 2020 |
| Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M β-lactamase A Judge, L Hu, B Sankaran, J Van Riper, BV Venkataram Prasad, ... Communications Biology 6 (1), 35, 2023 | 9 | 2023 |
| An active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M β-lactamase drug-resistance enzymes S Lu, L Hu, H Lin, A Judge, P Rivera, M Palaniappan, B Sankaran, ... Nature communications 13 (1), 6726, 2022 | 5 | 2022 |
| DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors R Jimmidi, S Chamakuri, S Lu, MN Ucisik, PJ Chen, KM Bohren, ... Communications Chemistry 6 (1), 164, 2023 | 3 | 2023 |
| Network of epistatic interactions in an enzyme active site revealed by large-scale deep mutational scanning A Judge, B Sankaran, L Hu, M Palaniappan, A Birgy, BVV Prasad, ... Proceedings of the National Academy of Sciences 121 (12), e2313513121, 2024 | 2 | 2024 |
| Exploiting the Carboxylate-Binding Pocket of β-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library S Park, J Fan, S Chamakuri, M Palaniappan, K Sharma, X Qin, J Wang, ... Journal of Medicinal Chemistry 67 (1), 620-642, 2023 | 1 | 2023 |
| DNA Shape Shifting as a Gene Therapy Tool JM Fogg, Q Wang, A Judge, E Stricker, BM Pettitt, L Zechiedrich Biophysical Journal 116 (3), 171a, 2019 | | 2019 |
Banumathi SankaranLBNL在 lbl.gov 的电子邮件经过验证
