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Sven Ullrich
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The SARS-CoV-2 main protease as drug target
S Ullrich, C Nitsche
Bioorganic & Medicinal Chemistry Letters 30 (17), 127377, 2020
6892020
Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir
S Ullrich, KB Ekanayake, G Otting, C Nitsche
Bioorganic & Medicinal Chemistry Letters 62, 128629, 2022
1762022
Antiviral cyclic peptides targeting the main protease of SARS-CoV-2
J Johansen-Leete, S Ullrich, SE Fry, R Frkic, MJ Bedding, A Aggarwal, ...
Chemical Science 13, 3826-3836, 2022
412022
SARS-CoV-2 papain-like protease: Structure, function and inhibition
S Ullrich, C Nitsche
ChemBioChem 23 (19), e202200327, 2022
322022
Challenges of short substrate analogues as SARS-CoV-2 main protease inhibitors
S Ullrich, VM Sasi, MC Mahawaththa, KB Ekanayake, R Morewood, ...
Bioorganic & Medicinal Chemistry Letters 50, 128333, 2021
292021
Predicting antiviral resistance mutations in SARS-CoV-2 main protease with computational and experimental screening
VM Sasi#, S Ullrich#, J Ton, SE Fry, J Johansen-Leete, RJ Payne, ...
Biochemistry 61 (22), 2495-2505, 2022
262022
Biocompatible and selective generation of bicyclic peptides
S Ullrich, J George, AE Coram, R Morewood, C Nitsche
Angewandte Chemie International Edition 61 (43), e202208400, 2022
142022
Bicyclic peptides: Paving the road for therapeutics of the future
S Ullrich, C Nitsche
Peptide Science 116 (2), e24326, 2024
52024
Probing ligand binding sites on large proteins by nuclear magnetic resonance spectroscopy of genetically encoded non-canonical amino acids
KB Ekanayake, MC Mahawaththa, H Qianzhu, EH Abdelkader, J George, ...
Journal of Medicinal Chemistry 66 (7), 5289-5304, 2023
52023
Site-selective generation of lanthanoid binding sites on proteins using 4-fluoro-2,6-dicyanopyridine
S Mekkattu Tharayil, MC Mahawaththa, A Feintuch, A Maleckis, S Ullrich, ...
Magnetic Resonance 3 (2), 169-182, 2022
12022
Exploiting hydrophobic amino acid scanning to develop cyclic peptide inhibitors of the SARS-CoV-2 main protease with antiviral activity
K Harrison, P Carlos, S Ullrich, A Aggarwal, J Johansen-Leete, ...
Chemistry - A European Journal, https://doi.org/10.1002/chem.202401606, 2024
2024
Phage-encoded bismuth bicycles: Instant access to targeted bioactive peptides
S Ullrich#, U Somathilake#, M Shang, C Nitsche
bioRxiv, http://doi.org/10.1101/2024.04.10.588800, 2024
2024
Modified peptides as viral protease inhibitors
S Ullrich
Australian National University, https://doi.org/10.25911/J0S0-2E61, 2024
2024
A RaPID response to SARS-CoV-2
S Ullrich, C Nitsche
Israel Journal of Chemistry, https://doi.org/10.1002/ijch.202300170, 2024
2024
4-Fluoro-2,6-dicyanopyridine
S Ullrich, C Nitsche
Encyclopedia of Reagents for Organic Synthesis, 2024
2024
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