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Douglas Millay
Douglas Millay
在 cchmc.org 的电子邮件经过验证
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Myomaker is a membrane activator of myoblast fusion and muscle formation
DP Millay, JR O’Rourke, LB Sutherland, S Bezprozvannaya, JM Shelton, ...
Nature 499 (7458), 301-305, 2013
5352013
Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy
DP Millay, MA Sargent, H Osinska, CP Baines, ER Barton, G Vuagniaux, ...
Nature medicine 14 (4), 442-447, 2008
4102008
Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism
DP Millay, SA Goonasekera, MA Sargent, M Maillet, BJ Aronow, ...
Proceedings of the National Academy of Sciences 106 (45), 19023-19028, 2009
2542009
Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy
SA Parsons, DP Millay, BJ Wilkins, OF Bueno, GL Tsika, JR Neilson, ...
Journal of Biological Chemistry 279 (25), 26192-26200, 2004
2352004
Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development
ME Quinn, Q Goh, M Kurosaka, DG Gamage, MJ Petrany, V Prasad, ...
Nature communications 8 (1), 15665, 2017
2332017
Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle
SA Goonasekera, CK Lam, DP Millay, MA Sargent, RJ Hajjar, EG Kranias, ...
The Journal of clinical investigation 121 (3), 1044-1052, 2011
2222011
Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers
MJ Petrany, CO Swoboda, C Sun, K Chetal, X Chen, MT Weirauch, ...
Nature communications 11 (1), 6374, 2020
2202020
Myomaker is essential for muscle regeneration
DP Millay, LB Sutherland, R Bassel-Duby, EN Olson
Genes & development 28 (15), 1641-1646, 2014
1822014
Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy
Q Goh, DP Millay
elife 6, e20007, 2017
1512017
A mouse model of rhabdomyosarcoma originating from the adipocyte lineage
ME Hatley, W Tang, MR Garcia, D Finkelstein, DP Millay, N Liu, J Graff, ...
Cancer cell 22 (4), 536-546, 2012
1472012
Myomaker and myomerger work independently to control distinct steps of membrane remodeling during myoblast fusion
E Leikina, DG Gamage, V Prasad, J Goykhberg, M Crowe, J Diao, ...
Developmental Cell 46 (6), 767-780. e7, 2018
1362018
Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy
SA Parsons, DP Millay, MA Sargent, EM McNally, JD Molkentin
The American journal of pathology 168 (6), 1975-1985, 2006
1282006
Myoblast fusion confusion: the resolution begins
SC Sampath, SC Sampath, DP Millay
Skeletal muscle 8, 1-10, 2018
1172018
Cell fusion: merging membranes and making muscle
MJ Petrany, DP Millay
Trends in cell biology 29 (12), 964-973, 2019
1122019
Myonuclear accretion is a determinant of exercise-induced remodeling in skeletal muscle
Q Goh, T Song, MJ Petrany, AAW Cramer, C Sun, S Sadayappan, SJ Lee, ...
Elife 8, e44876, 2019
922019
Structure–function analysis of myomaker domains required for myoblast fusion
DP Millay, DG Gamage, ME Quinn, YL Min, Y Mitani, R Bassel-Duby, ...
Proceedings of the National Academy of Sciences 113 (8), 2116-2121, 2016
882016
CREST-a large and diverse superfamily of putative transmembrane hydrolases
J Pei, DP Millay, EN Olson, NV Grishin
Biology direct 6, 1-17, 2011
872011
TGFβ signaling curbs cell fusion and muscle regeneration
F Girardi, A Taleb, M Ebrahimi, A Datye, DG Gamage, C Peccate, ...
Nature communications 12 (1), 750, 2021
862021
Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice
ER Wissing, DP Millay, G Vuagniaux, JD Molkentin
Neuromuscular Disorders 20 (11), 753-760, 2010
852010
Nuclear numbers in syncytial muscle fibers promote size but limit the development of larger myonuclear domains
AAW Cramer, V Prasad, E Eftestøl, T Song, KA Hansson, HF Dugdale, ...
Nature communications 11 (1), 6287, 2020
762020
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