IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis M Rokavec, MG Öner, H Li, R Jackstadt, L Jiang, D Lodygin, M Kaller, ... The Journal of clinical investigation 124 (4), 1853-1867, 2014 | 802 | 2014 |
The p53/miR-34 axis in development and disease M Rokavec, H Li, L Jiang, H Hermeking Journal of molecular cell biology 6 (3), 214-230, 2014 | 388 | 2014 |
IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis M Rokavec, W Wu, JL Luo Molecular cell 45 (6), 777-789, 2012 | 172 | 2012 |
Antagonistic effects of p53 and HIF1A on microRNA-34a regulation of PPP1R11 and STAT3 and hypoxia-induced epithelial to mesenchymal transition in colorectal cancer cells H Li, M Rokavec, L Jiang, D Horst, H Hermeking Gastroenterology 153 (2), 505-520, 2017 | 158 | 2017 |
Cellular model of colon cancer progression reveals signatures of mRNAs, miRNA, lncRNAs, and epigenetic modifications associated with metastasis M Rokavec, D Horst, H Hermeking Cancer research 77 (8), 1854-1867, 2017 | 102 | 2017 |
Pan-cancer EMT-signature identifies RBM47 down-regulation during colorectal cancer progression M Rokavec, M Kaller, D Horst, H Hermeking Scientific Reports 7 (1), 4687, 2017 | 84 | 2017 |
Characterization of a p53/miR-34a/CSF1R/STAT3 feedback loop in colorectal cancer X Shi, M Kaller, M Rokavec, T Kirchner, D Horst, H Hermeking Cellular and molecular gastroenterology and hepatology 10 (2), 391-418, 2020 | 75 | 2020 |
The p53/microRNA connection in gastrointestinal cancer M Rokavec, H Li, L Jiang, H Hermeking Clinical and experimental gastroenterology, 395-413, 2014 | 66 | 2014 |
Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis C Liu, M Rokavec, Z Huang, H Hermeking Cell Death & Differentiation 30 (7), 1771-1785, 2023 | 61 | 2023 |
Estrogen‐mediated downregulation of CD24 in breast cancer cells BA Kaipparettu, S Malik, SD Konduri, W Liu, M Rokavec, H van der Kuip, ... International journal of cancer 123 (1), 66-72, 2008 | 49 | 2008 |
Combined inactivation of TP53 and MIR34A promotes colorectal cancer development and progression in mice via increasing levels of IL6R and PAI1 MG Öner, M Rokavec, M Kaller, N Bouznad, D Horst, T Kirchner, ... Gastroenterology 155 (6), 1868-1882, 2018 | 48 | 2018 |
lnflammation-induced epigenetic switches in cancer M Rokavec, MG Öner, H Hermeking Cellular and molecular life sciences 73, 23-39, 2016 | 45 | 2016 |
A Novel Polymorphism in the Promoter Region of ERBB4 Is Associated with Breast and Colorectal Cancer Risk M Rokavec, C Justenhoven, W Schroth, MA Istrate, S Haas, HP Fischer, ... Clinical cancer research 13 (24), 7506-7514, 2007 | 40 | 2007 |
Soluble IL6R represents a miR-34a target: potential implications for the recently identified IL-6R/STAT3/miR-34a feed-back loop H Li, M Rokavec, H Hermeking Oncotarget 6 (16), 14026, 2015 | 31 | 2015 |
Paracrine induction of epithelial-mesenchymal transition between colorectal cancer cells and its suppression by a p53/miR-192/215/NID1 axis M Rokavec, N Bouznad, H Hermeking Cellular and Molecular Gastroenterology and Hepatology 7 (4), 783-802, 2019 | 27 | 2019 |
AP4 suppresses DNA damage, chromosomal instability and senescence via inducing MDC1/Mediator of DNA damage Checkpoint 1 and repressing MIR22HG/miR-22-3p J Chou, M Kaller, S Jaeckel, M Rokavec, H Hermeking Molecular Cancer 21 (1), 120, 2022 | 24 | 2022 |
A Polymorphism in the TC21 Promoter Associates with an Unfavorable Tamoxifen Treatment Outcome in Breast Cancer M Rokavec, W Schroth, SMC Amaral, P Fritz, L Antoniadou, D Glavac, ... Cancer research 68 (23), 9799-9808, 2008 | 23 | 2008 |
Disease modeling on tumor organoids implicates AURKA as a therapeutic target in liver metastatic colorectal cancer SL Boos, LP Loevenich, S Vosberg, T Engleitner, R Öllinger, J Kumbrink, ... Cellular and Molecular Gastroenterology and Hepatology 13 (2), 517-540, 2022 | 22 | 2022 |
SMAD4 Loss Induces c-MYC–Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis LP Loevenich, M Tschurtschenthaler, M Rokavec, MG Silva, ... Cancer research 82 (24), 4604-4623, 2022 | 13 | 2022 |
14-3-3σ Functions as an Intestinal Tumor Suppressor M Winter, M Rokavec, H Hermeking Cancer Research 81 (13), 3621-3634, 2021 | 10 | 2021 |