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Karthik B. Jeganathan
Karthik B. Jeganathan
Assistant Professor Pediatric and Adolescent Medicine, Research - Supervisor, Mayo Clinic, Rochester
在 mayo.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
DJ Baker, BG Childs, M Durik, ME Wijers, CJ Sieben, J Zhong, ...
Nature 530 (7589), 184-189, 2016
24922016
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
DJ Baker, KB Jeganathan, JD Cameron, M Thompson, S Juneja, ...
Nature genetics 36 (7), 744-749, 2004
8602004
Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency
DJ Baker, C Perez-Terzic, F Jin, KS Pitel, NJ Niederländer, K Jeganathan, ...
Nature cell biology 10 (7), 825-836, 2008
4552008
Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation
JR Babu, KB Jeganathan, DJ Baker, X Wu, N Kang-Decker, ...
The Journal of cell biology 160 (3), 341-353, 2003
4352003
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIα
MM Dawlaty, L Malureanu, KB Jeganathan, E Kao, C Sustmann, S Tahk, ...
Cell 133 (1), 103-115, 2008
3772008
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan
DJ Baker, MM Dawlaty, T Wijshake, KB Jeganathan, L Malureanu, ...
Nature cell biology 15 (1), 96-102, 2013
3192013
Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis
K Jeganathan, L Malureanu, DJ Baker, SC Abraham, JM Van Deursen
The Journal of cell biology 179 (2), 255-267, 2007
2702007
Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity
DJ Baker, F Jin, KB Jeganathan, JM van Deursen
Cancer cell 16 (6), 475-486, 2009
2542009
SIRT 2 induces the checkpoint kinase BubR1 to increase lifespan
BJ North, MA Rosenberg, KB Jeganathan, AV Hafner, S Michan, J Dai, ...
The EMBO journal 33 (13), 1438-1453, 2014
2392014
Overexpression of the E2 ubiquitin–conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation
JH Van Ree, KB Jeganathan, L Malureanu, JM Van Deursen
Journal of Cell Biology 188 (1), 83-100, 2010
2252010
BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/CCdc20 in interphase
LA Malureanu, KB Jeganathan, M Hamada, L Wasilewski, J Davenport, ...
Developmental cell 16 (1), 118-131, 2009
2202009
Early aging–associated phenotypes in Bub3/Rae1 haploinsufficient mice
DJ Baker, KB Jeganathan, L Malureanu, C Perez-Terzic, A Terzic, ...
The Journal of cell biology 172 (4), 529-540, 2006
2112006
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation
RM Ricke, KB Jeganathan, JM van Deursen
Journal of Cell Biology 193 (6), 1049-1064, 2011
2062011
The Rae1–Nup98 complex prevents aneuploidy by inhibiting securin degradation
KB Jeganathan, L Malureanu, JM Van Deursen
Nature 438 (7070), 1036-1039, 2005
2022005
p21 produces a bioactive secretome that places stressed cells under immunosurveillance
I Sturmlechner, C Zhang, CC Sine, EJ van Deursen, KB Jeganathan, ...
Science 374 (6567), eabb3420, 2021
1572021
Spartan deficiency causes genomic instability and progeroid phenotypes
RS Maskey, MS Kim, DJ Baker, B Childs, LA Malureanu, KB Jeganathan, ...
Nature communications 5 (1), 5744, 2014
1272014
Ran-dependent docking of importin-β to RanBP2/Nup358 filaments is essential for protein import and cell viability
M Hamada, A Haeger, KB Jeganathan, JH van Ree, L Malureanu, ...
Journal of Cell Biology 194 (4), 597-612, 2011
1242011
Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression
RM Ricke, KB Jeganathan, L Malureanu, AM Harrison, JM Van Deursen
Journal of Cell Biology 199 (6), 931-949, 2012
1062012
L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage
S Nowsheen, K Aziz, A Aziz, M Deng, B Qin, K Luo, KB Jeganathan, ...
Nature cell biology 20 (4), 455-464, 2018
1022018
Cdc20 is critical for meiosis I and fertility of female mice
F Jin, M Hamada, L Malureanu, KB Jeganathan, W Zhou, DE Morbeck, ...
PLoS genetics 6 (9), e1001147, 2010
1002010
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