Naturally occurring p16Ink4a-positive cells shorten healthy lifespan DJ Baker, BG Childs, M Durik, ME Wijers, CJ Sieben, J Zhong, ... Nature 530 (7589), 184-189, 2016 | 2492 | 2016 |
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice DJ Baker, KB Jeganathan, JD Cameron, M Thompson, S Juneja, ... Nature genetics 36 (7), 744-749, 2004 | 860 | 2004 |
Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency DJ Baker, C Perez-Terzic, F Jin, KS Pitel, NJ Niederländer, K Jeganathan, ... Nature cell biology 10 (7), 825-836, 2008 | 455 | 2008 |
Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation JR Babu, KB Jeganathan, DJ Baker, X Wu, N Kang-Decker, ... The Journal of cell biology 160 (3), 341-353, 2003 | 435 | 2003 |
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIα MM Dawlaty, L Malureanu, KB Jeganathan, E Kao, C Sustmann, S Tahk, ... Cell 133 (1), 103-115, 2008 | 377 | 2008 |
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan DJ Baker, MM Dawlaty, T Wijshake, KB Jeganathan, L Malureanu, ... Nature cell biology 15 (1), 96-102, 2013 | 319 | 2013 |
Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis K Jeganathan, L Malureanu, DJ Baker, SC Abraham, JM Van Deursen The Journal of cell biology 179 (2), 255-267, 2007 | 270 | 2007 |
Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity DJ Baker, F Jin, KB Jeganathan, JM van Deursen Cancer cell 16 (6), 475-486, 2009 | 254 | 2009 |
SIRT 2 induces the checkpoint kinase BubR1 to increase lifespan BJ North, MA Rosenberg, KB Jeganathan, AV Hafner, S Michan, J Dai, ... The EMBO journal 33 (13), 1438-1453, 2014 | 239 | 2014 |
Overexpression of the E2 ubiquitin–conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation JH Van Ree, KB Jeganathan, L Malureanu, JM Van Deursen Journal of Cell Biology 188 (1), 83-100, 2010 | 225 | 2010 |
BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/CCdc20 in interphase LA Malureanu, KB Jeganathan, M Hamada, L Wasilewski, J Davenport, ... Developmental cell 16 (1), 118-131, 2009 | 220 | 2009 |
Early aging–associated phenotypes in Bub3/Rae1 haploinsufficient mice DJ Baker, KB Jeganathan, L Malureanu, C Perez-Terzic, A Terzic, ... The Journal of cell biology 172 (4), 529-540, 2006 | 211 | 2006 |
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation RM Ricke, KB Jeganathan, JM van Deursen Journal of Cell Biology 193 (6), 1049-1064, 2011 | 206 | 2011 |
The Rae1–Nup98 complex prevents aneuploidy by inhibiting securin degradation KB Jeganathan, L Malureanu, JM Van Deursen Nature 438 (7070), 1036-1039, 2005 | 202 | 2005 |
p21 produces a bioactive secretome that places stressed cells under immunosurveillance I Sturmlechner, C Zhang, CC Sine, EJ van Deursen, KB Jeganathan, ... Science 374 (6567), eabb3420, 2021 | 157 | 2021 |
Spartan deficiency causes genomic instability and progeroid phenotypes RS Maskey, MS Kim, DJ Baker, B Childs, LA Malureanu, KB Jeganathan, ... Nature communications 5 (1), 5744, 2014 | 127 | 2014 |
Ran-dependent docking of importin-β to RanBP2/Nup358 filaments is essential for protein import and cell viability M Hamada, A Haeger, KB Jeganathan, JH van Ree, L Malureanu, ... Journal of Cell Biology 194 (4), 597-612, 2011 | 124 | 2011 |
Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression RM Ricke, KB Jeganathan, L Malureanu, AM Harrison, JM Van Deursen Journal of Cell Biology 199 (6), 931-949, 2012 | 106 | 2012 |
L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage S Nowsheen, K Aziz, A Aziz, M Deng, B Qin, K Luo, KB Jeganathan, ... Nature cell biology 20 (4), 455-464, 2018 | 102 | 2018 |
Cdc20 is critical for meiosis I and fertility of female mice F Jin, M Hamada, L Malureanu, KB Jeganathan, W Zhou, DE Morbeck, ... PLoS genetics 6 (9), e1001147, 2010 | 100 | 2010 |