Chemotherapy-resistant human acute myeloid leukemia cells are not enriched for leukemic stem cells but require oxidative metabolism T Farge, E Saland, F De Toni, N Aroua, M Hosseini, R Perry, C Bosc, ... Cancer discovery 7 (7), 716-735, 2017 | 727 | 2017 |
Relapse-fated latent diagnosis subclones in acute B lineage leukemia are drug tolerant and possess distinct metabolic programs SM Dobson, L García-Prat, RJ Vanner, J Wintersinger, E Waanders, Z Gu, ... Cancer discovery 10 (4), 568-587, 2020 | 94 | 2020 |
Skin equivalents: skin from reconstructions as models to study skin development and diseases N Ali, M Hosseini, S Vainio, A Taïeb, M Cario‐André, HR Rezvani British Journal of Dermatology 173 (2), 391-403, 2015 | 94 | 2015 |
Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia L Stuani, M Sabatier, E Saland, G Cognet, N Poupin, C Bosc, FA Castelli, ... Journal of Experimental Medicine 218 (5), e20200924, 2021 | 77 | 2021 |
NADPH oxidase-1 plays a key role in keratinocyte responses to UV radiation and UVB-induced skin carcinogenesis H Raad, M Serrano-Sanchez, G Harfouche, W Mahfouf, D Bortolotto, ... Journal of investigative Dermatology 137 (6), 1311-1321, 2017 | 65 | 2017 |
Extracellular ATP and CD39 activate cAMP-mediated mitochondrial stress response to promote cytarabine resistance in acute myeloid leukemia N Aroua, E Boet, M Ghisi, ML Nicolau-Travers, E Saland, R Gwilliam, ... Cancer Discovery 10 (10), 1544-1565, 2020 | 59 | 2020 |
Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis A Subedi, Q Liu, DM Ayyathan, D Sharon, S Cathelin, M Hosseini, C Xu, ... Cell Stem Cell 28 (10), 1851-1867. e8, 2021 | 58 | 2021 |
Energy metabolism rewiring precedes UVB-induced primary skin tumor formation M Hosseini, L Dousset, W Mahfouf, M Serrano-Sanchez, ... Cell reports 23 (12), 3621-3634, 2018 | 58 | 2018 |
Targeting the SUMO Pathway Primes All-trans Retinoic Acid–Induced Differentiation of Nonpromyelocytic Acute Myeloid Leukemias H Baik, M Boulanger, M Hosseini, J Kowalczyk, S Zaghdoudi, T Salem, ... Cancer research 78 (10), 2601-2613, 2018 | 53 | 2018 |
Targeting myeloperoxidase disrupts mitochondrial redox balance and overcomes cytarabine resistance in human acute myeloid leukemia M Hosseini, HR Rezvani, N Aroua, C Bosc, T Farge, E Saland, ... Cancer Research 79 (20), 5191-5203, 2019 | 52 | 2019 |
Premature skin aging features rescued by inhibition of NADPH oxidase activity in XPC-deficient mice M Hosseini, W Mahfouf, M Serrano-Sanchez, H Raad, G Harfouche, ... Journal of Investigative Dermatology 135 (4), 1108-1118, 2015 | 41 | 2015 |
Energy metabolism in skin cancers: a therapeutic perspective M Hosseini, Z Kasraian, HR Rezvani Biochimica et Biophysica Acta (BBA)-Bioenergetics 1858 (8), 712-722, 2017 | 37 | 2017 |
Inhibition of p38 MAPK signaling augments skin tumorigenesis via NOX2 driven ROS generation L Liu, HR Rezvani, JH Back, M Hosseini, X Tang, Y Zhu, W Mahfouf, ... PloS one 9 (5), e97245, 2014 | 35 | 2014 |
Oxidative and energy metabolism as potential clues for clinical heterogeneity in nucleotide excision repair disorders M Hosseini, K Ezzedine, A Taieb, HR Rezvani Journal of Investigative Dermatology 135 (2), 341-351, 2015 | 28 | 2015 |
UVB-induced DHODH upregulation, which is driven by STAT3, is a promising target for chemoprevention and combination therapy of photocarcinogenesis M Hosseini, L Dousset, P Michon, W Mahfouf, E Muzotte, V Bergeron, ... Oncogenesis 8 (10), 52, 2019 | 17 | 2019 |
Loss of epidermal HIF-1α blocks UVB-induced tumorigenesis by affecting DNA repair capacity and oxidative stress W Mahfouf, M Hosseini, E Muzotte, M Serrano-Sanchez, L Dousset, ... Journal of Investigative Dermatology 139 (9), 2016-2028. e7, 2019 | 15 | 2019 |
Targeting STAT5 signaling overcomes resistance to IDH inhibitors in acute myeloid leukemia through suppression of stemness ACH Liu, S Cathelin, Y Yang, DL Dai, DM Ayyathan, M Hosseini, ... Cancer Research 82 (23), 4325-4339, 2022 | 7 | 2022 |
Coordinating effect of VEGFC and oleic acid participates to tumor lymphangiogenesis F Morfoisse, F De Toni, J Nigri, M Hosseini, A Zamora, F Tatin, F Pujol, ... Cancers 13 (12), 2851, 2021 | 6 | 2021 |
Label-free detection of mitochondrial activity with Microwave Dielectric Spectroscopy Research Article G Poiroux, D Dubuc, M Hosseini, F Artis, A Tamra, M Tosolini, F Pont, ... International Journal of Biotechnology and Bioengineering 6 (5), 2020 | 5 | 2020 |
Multiomic profiling of central nervous system leukemia identifies mRNA translation as a therapeutic target RJ Vanner, SM Dobson, OI Gan, J McLeod, EM Schoof, I Grandal, ... Blood cancer discovery 3 (1), 16-31, 2022 | 4 | 2022 |