Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells K Yusa, ST Rashid, H Strick-Marchand, I Varela, PQ Liu, DE Paschon, ... Nature 478 (7369), 391-394, 2011 | 823 | 2011 |
Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells ST Rashid, S Corbineau, N Hannan, SJ Marciniak, E Miranda, ... The Journal of clinical investigation 120 (9), 3127-3136, 2010 | 742 | 2010 |
Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development T Touboul, NRF Hannan, S Corbineau, A Martinez, C Martinet, ... Hepatology 51 (5), 1754-1765, 2010 | 613 | 2010 |
Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury RP Fordham, S Yui, NRF Hannan, C Soendergaard, A Madgwick, ... Cell stem cell 13 (6), 734-744, 2013 | 420 | 2013 |
Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation F Sampaziotis, M Cardoso de Brito, P Madrigal, A Bertero, K Saeb-Parsy, ... Nature biotechnology 33 (8), 845-852, 2015 | 404 | 2015 |
Production of hepatocyte-like cells from human pluripotent stem cells NRF Hannan, CP Segeritz, T Touboul, L Vallier Nature protocols 8 (2), 430-437, 2013 | 390 | 2013 |
Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways L Vallier, T Touboul, Z Chng, M Brimpari, N Hannan, E Millan, ... PloS one 4 (6), e6082, 2009 | 334 | 2009 |
Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids F Sampaziotis, AW Justin, OC Tysoe, S Sawiak, EM Godfrey, SS Upponi, ... Nature medicine 23 (8), 954-963, 2017 | 306 | 2017 |
Interaction of Salmonella enterica serovar Typhimurium with intestinal organoids derived from human induced pluripotent stem cells JL Forbester, D Goulding, L Vallier, N Hannan, C Hale, D Pickard, ... Infection and immunity 83 (7), 2926-2934, 2015 | 271 | 2015 |
Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture RL Gieseck III, NRF Hannan, R Bort, NA Hanley, RAL Drake, ... PloS one 9 (1), e86372, 2014 | 244 | 2014 |
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ... Cell stem cell 28 (5), 816-832, 2021 | 229 | 2021 |
Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors S Brown, A Teo, S Pauklin, N Hannan, CHH Cho, B Lim, L Vardy, ... Stem cells 29 (8), 1176-1185, 2011 | 224 | 2011 |
Activation of the selenoprotein SEPS1 gene expression by pro-inflammatory cytokines in HepG2 cells Y Gao, NRF Hannan, S Wanyonyi, N Konstantopolous, J Pagnon, ... Cytokine 33 (5), 246-251, 2006 | 143 | 2006 |
Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells F Sampaziotis, MC de Brito, I Geti, A Bertero, NRF Hannan, L Vallier Nature protocols 12 (4), 814-827, 2017 | 109 | 2017 |
Generation of multipotent foregut stem cells from human pluripotent stem cells NRF Hannan, RP Fordham, YA Syed, V Moignard, A Berry, R Bautista, ... Stem cell reports 1 (4), 293-306, 2013 | 108 | 2013 |
Intestinal organoids for modelling intestinal development and disease KL Fair, J Colquhoun, NRF Hannan Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 100 | 2018 |
Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs A Bertero, M Pawlowski, D Ortmann, K Snijders, L Yiangou, ... Development 143 (23), 4405-4418, 2016 | 99 | 2016 |
Regional Differences in Human Biliary Tissues and Corresponding In Vitro–Derived Organoids CA Rimland, SG Tilson, CM Morell, RA Tomaz, WY Lu, SE Adams, ... Hepatology 73 (1), 247-267, 2021 | 98 | 2021 |
Inhibition of activin/nodal signalling is necessary for pancreatic differentiation of human pluripotent stem cells CHH Cho, NRF Hannan, FM Docherty, HM Docherty, M Joåo Lima, ... Diabetologia 55, 3284-3295, 2012 | 80 | 2012 |
hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency CP Segeritz, ST Rashid, MC de Brito, MP Serra, A Ordonez, CM Morell, ... Journal of hepatology 69 (4), 851-860, 2018 | 57 | 2018 |