Tctex‐1 controls ciliary resorption by regulating branched actin polymerization and endocytosis M Saito, W Otsu, KS Hsu, JZ Chuang, T Yanagisawa, V Shieh, T Kaitsuka, ... EMBO reports 18 (8), 1460-1472, 2017 | 56 | 2017 |
CLIC4 regulates apical exocytosis and renal tube luminogenesis through retromer-and actin-mediated endocytic trafficking SY Chou, KS Hsu, W Otsu, YC Hsu, YC Luo, C Yeh, SS Shehab, J Chen, ... Nature communications 7 (1), 10412, 2016 | 53 | 2016 |
A new class of endoplasmic reticulum export signal ΦXΦXΦ for transmembrane proteins and its selective interaction with Sec24C W Otsu, T Kurooka, Y Otsuka, K Sato, M Inaba Journal of Biological Chemistry 288 (25), 18521-18532, 2013 | 24 | 2013 |
Retinal pigment epithelium-specific CLIC4 mutant is a mouse model of dry age-related macular degeneration JZ Chuang, N Yang, N Nakajima, W Otsu, C Fu, HH Yang, MP Lee, ... Nature communications 13 (1), 374, 2022 | 23 | 2022 |
A triterpenoid Nrf2 activator, RS9, promotes LC3-associated phagocytosis of photoreceptor outer segments in a p62-independent manner Y Saito, T Yako, W Otsu, S Nakamura, Y Inoue, A Muramatsu, ... Free Radical Biology and Medicine 152, 235-247, 2020 | 23 | 2020 |
Cigarette smoke extract and heated tobacco products promote ferritin cleavage and iron accumulation in human corneal epithelial cells W Otsu, K Ishida, N Chinen, S Nakamura, M Shimazawa, H Tsusaki, ... Scientific Reports 11 (1), 18555, 2021 | 22 | 2021 |
The late endosomal pathway regulates the ciliary targeting of tetraspanin protein peripherin 2 W Otsu, YC Hsu, JZ Chuang, CH Sung Journal of Neuroscience 39 (18), 3376-3393, 2019 | 21 | 2019 |
CLIC4 regulates late endosomal trafficking and matrix degradation activity of MMP14 at focal adhesions in RPE cells KS Hsu, W Otsu, Y Li, HC Wang, S Chen, SH Tsang, JZ Chuang, ... Scientific reports 9 (1), 12247, 2019 | 20 | 2019 |
Lipid droplet accumulation promotes RPE dysfunction T Yako, W Otsu, S Nakamura, M Shimazawa, H Hara International Journal of Molecular Sciences 23 (3), 1790, 2022 | 18 | 2022 |
Blue light-emitting diode irradiation promotes transcription factor EB-mediated lysosome biogenesis and lysosomal cell death in murine photoreceptor-derived cells W Otsu, K Ishida, S Nakamura, M Shimazawa, H Tsusaki, H Hara Biochemical and biophysical research communications 526 (2), 479-484, 2020 | 17 | 2020 |
Cholesterol-binding protein TSPO2 coordinates maturation and proliferation of terminally differentiating erythroblasts B Kiatpakdee, K Sato, Y Otsuka, N Arashiki, Y Chen, T Tsumita, W Otsu, ... Journal of Biological Chemistry 295 (23), 8048-8063, 2020 | 15 | 2020 |
Mitochondria dynamics in the aged mice eye and the role in the RPE phagocytosis T Yako, M Nakamura, W Otsu, S Nakamura, M Shimazawa, H Hara Experimental Eye Research 213, 108800, 2021 | 13 | 2021 |
Progranulin deficiency in Iba-1+ myeloid cells exacerbates choroidal neovascularization by perturbation of lysosomal function and abnormal inflammation K Takahashi, S Nakamura, W Otsu, M Shimazawa, H Hara Journal of neuroinflammation 18, 1-16, 2021 | 13 | 2021 |
Clathrin-mediated endocytosis of mammalian erythroid AE1 anion exchanger facilitated by a YXXΦ or a noncanonical YXXXΦ motif in the N-terminal stretch CC Wang, K Sato, Y Otsuka, W Otsu, M Inaba Journal of Veterinary Medical Science 74 (1), 17-25, 2012 | 13 | 2012 |
Modulatory roles of NHERF1 and NHERF2 in cell surface expression of the glutamate transporter GLAST K Sato, W Otsu, Y Otsuka, M Inaba Biochemical and biophysical research communications 430 (2), 839-845, 2013 | 12 | 2013 |
Anti-vascular endothelial growth factor antibody limits the vascular leakage and decreases subretinal fibrosis in a cynomolgus monkey choroidal neovascularization model S Inagaki, M Shimazawa, K Hamaguchi, W Otsu, T Araki, Y Sasaki, ... Current Neurovascular Research 17 (4), 420-428, 2020 | 10 | 2020 |
Free-radical scavenger NSP-116 protects the corneal epithelium against UV-A and blue LED light exposure K Ishida, T Yako, M Tanaka, W Otsu, S Nakamura, M Shimazawa, ... Biological and Pharmaceutical Bulletin 44 (7), 937-946, 2021 | 6 | 2021 |
Establishment of a pigmented murine model abundant with characteristics of retinal vein occlusion S Miyagi, A Nishinaka, T Yamamoto, W Otsu, S Nakamura, M Shimazawa, ... Experimental Eye Research 204, 108441, 2021 | 6 | 2021 |
Crocetin protects against mitochondrial damage induced by UV-A irradiation in corneal epithelial cell line HCE-T cells W Otsu, T Yako, E Sugisawa, S Nakamura, H Tsusaki, N Umigai, ... Journal of Pharmacological Sciences 150 (4), 279-288, 2022 | 5 | 2022 |
The pathological association between the anterior eye segment and the retina in a murine model of neovascular glaucoma A Nishinaka, M Tanaka, K Aoshima, A Kuriyama, T Sasaki, W Otsu, ... The FASEB Journal 36 (6), e22323, 2022 | 5 | 2022 |