| The regulation and functions of DNA and RNA G-quadruplexes D Varshney, J Spiegel, K Zyner, D Tannahill, S Balasubramanian Nature reviews Molecular cell biology 21 (8), 459-474, 2020 | 819 | 2020 |
| The structure and function of DNA G-quadruplexes J Spiegel, S Adhikari, S Balasubramanian Trends in Chemistry 2 (2), 123-136, 2020 | 637 | 2020 |
| Hydrocarbon stapled peptides as modulators of biological function PM Cromm, J Spiegel, TN Grossmann ACS chemical biology 10 (6), 1362-1375, 2015 | 293 | 2015 |
| Small-molecule modulation of Ras signaling J Spiegel, PM Cromm, G Zimmermann, TN Grossmann, H Waldmann Nature chemical biology 10 (8), 613-622, 2014 | 269 | 2014 |
| Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing R Hänsel-Hertsch, J Spiegel, G Marsico, D Tannahill, S Balasubramanian Nature protocols 13 (3), 551-564, 2018 | 239 | 2018 |
| DNA G-quadruplex structures mold the DNA methylome SQ Mao, AT Ghanbarian, J Spiegel, S Martínez Cuesta, D Beraldi, ... Nature structural & molecular biology 25 (10), 951-957, 2018 | 222 | 2018 |
| Azapeptides and their therapeutic potential C Proulx, D Sabatino, R Hopewell, J Spiegel, Y García Ramos, WD Lubell Future medicinal chemistry 3 (9), 1139-1164, 2011 | 190 | 2011 |
| G-quadruplexes are transcription factor binding hubs in human chromatin J Spiegel, SM Cuesta, S Adhikari, R Hänsel-Hertsch, D Tannahill, ... Genome biology 22 (1), 117, 2021 | 147 | 2021 |
| Direct Targeting of Rab‐GTPase–Effector Interactions J Spiegel, PM Cromm, A Itzen, RS Goody, TN Grossmann, H Waldmann Angewandte Chemie International Edition 53 (9), 2498-2503, 2014 | 104 | 2014 |
| Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides PM Cromm, S Schaubach, J Spiegel, A Fürstner, TN Grossmann, ... Nature communications 7 (1), 11300, 2016 | 103 | 2016 |
| Chemical profiling of DNA G-quadruplex-interacting proteins in live cells X Zhang, J Spiegel, S Martínez Cuesta, S Adhikari, S Balasubramanian Nature Chemistry 13 (7), 626-633, 2021 | 89 | 2021 |
| Direct modulation of small GTPase activity and function PM Cromm, J Spiegel, TN Grossmann, H Waldmann Angewandte Chemie International Edition 54 (46), 13516-13537, 2015 | 84 | 2015 |
| Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase PM Cromm, J Spiegel, P Küchler, L Dietrich, J Kriegesmann, M Wendt, ... ACS chemical biology 11 (8), 2375-2382, 2016 | 81 | 2016 |
| Cyclic aza-peptide integrin ligand synthesis and biological activity J Spiegel, C Mas-Moruno, H Kessler, WD Lubell The Journal of organic chemistry 77 (12), 5271-5278, 2012 | 56 | 2012 |
| DNA G-quadruplex recognition in vitro and in live cells by a structure-specific nanobody S Galli, L Melidis, SM Flynn, D Varshney, A Simeone, J Spiegel, ... Journal of the American Chemical Society 144 (50), 23096-23103, 2022 | 28 | 2022 |
| Chem-map profiles drug binding to chromatin in cells Z Yu, J Spiegel, L Melidis, WWI Hui, X Zhang, A Radzevičius, ... Nature biotechnology 41 (9), 1265-1271, 2023 | 19 | 2023 |
| Direkte Modulation von Rab‐GTPase‐Effektor‐Wechselwirkungen J Spiegel, PM Cromm, A Itzen, RS Goody, TN Grossmann, H Waldmann Angewandte Chemie 126 (9), 2531-2536, 2014 | 9 | 2014 |
| Iminoboronate-mediated peptide cyclization with lysine homologues K Li, J Gao Synlett 28 (15), 1913-1916, 2017 | 7 | 2017 |
| Direkte Modulation von Aktivität und Funktion kleiner GTPasen PM Cromm, J Spiegel, TN Grossmann, H Waldmann Angewandte Chemie 127 (46), 13718-13741, 2015 | 7 | 2015 |
| Synthese und Evaluierung stabilisierter Bindungsepitope zur Adressierung kleiner GTPasen J Spiegel Dissertation, Dortmund, Technische Universität, 2016, 2016 | 1 | 2016 |
