Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical … TA Rasmussen, M Tolstrup, CR Brinkmann, R Olesen, C Erikstrup, ... The lancet HIV 1 (1), e13-e21, 2014 | 677 | 2014 |
HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects M J Buzón, M Massanella, JM Llibre, A Esteve, V Dahl, MC Puertas, ... Nature medicine 16 (4), 460-465, 2010 | 655 | 2010 |
HIV-1 persistence in CD4+ T cells with stem cell–like properties MJ Buzon, H Sun, C Li, A Shaw, K Seiss, Z Ouyang, E Martin-Gayo, ... Nature medicine 20 (2), 139-142, 2014 | 479 | 2014 |
Long-term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells MJ Buzon, E Martin-Gayo, F Pereyra, Z Ouyang, H Sun, JZ Li, M Piovoso, ... Journal of virology 88 (17), 10056-10065, 2014 | 313 | 2014 |
Increased coronary atherosclerosis and immune activation in HIV-1 elite controllers F Pereyra, J Lo, VA Triant, J Wei, MJ Buzon, KV Fitch, J Hwang, ... Aids 26 (18), 2409-2412, 2012 | 248 | 2012 |
A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes RB Jones, S Mueller, R O’Connor, K Rimpel, DD Sloan, D Karel, ... PLoS pathogens 12 (4), e1005545, 2016 | 179 | 2016 |
Short-course toll-like receptor 9 agonist treatment impacts innate immunity and plasma viremia in individuals with human immunodeficiency virus infection L Vibholm, MH Schleimann, JF Højen, T Benfield, R Offersen, ... Clinical Infectious Diseases 64 (12), 1686-1695, 2017 | 152 | 2017 |
Reactivation of latent HIV-1 in central memory CD4+T cells through TLR-1/2 stimulation CL Novis, NM Archin, MJ Buzon, E Verdin, JL Round, M Lichterfeld, ... Retrovirology 10, 1-15, 2013 | 148 | 2013 |
Latency reversal agents affect differently the latent reservoir present in distinct CD4+ T subpopulations J Grau-Expósito, L Luque-Ballesteros, J Navarro, A Curran, J Burgos, ... PLoS pathogens 15 (8), e1007991, 2019 | 144 | 2019 |
Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study JM Llibre, MJ Buzón, M Massanella, A Esteve, V Dahl, MC Puertas, ... Antiviral therapy 17 (2), 355-364, 2012 | 144 | 2012 |
Infrequent Recovery of HIV from but Robust Exogenous Infection of Activated CD4+ T Cells in HIV Elite Controllers B Julg, F Pereyra, MJ Buzon, A Piechocka-Trocha, MJ Clark, BM Baker, ... Clinical infectious diseases 51 (2), 233-238, 2010 | 136 | 2010 |
Peripheral and lung resident memory T cell responses against SARS-CoV-2 J Grau-Expósito, N Sánchez-Gaona, N Massana, M Suppi, ... Nature communications 12 (1), 3010, 2021 | 131 | 2021 |
CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells M Abdel-Mohsen, L Kuri-Cervantes, J Grau-Exposito, AM Spivak, RA Nell, ... Science translational medicine 10 (437), eaar6759, 2018 | 126 | 2018 |
Integrated and Total HIV-1 DNA Predict Ex Vivo Viral Outgrowth M Kiselinova, W De Spiegelaere, MJ Buzon, E Malatinkova, M Lichterfeld, ... PLoS pathogens 12 (3), e1005472, 2016 | 115 | 2016 |
Recommendations for measuring HIV reservoir size in cure-directed clinical trials M Abdel-Mohsen, D Richman, RF Siliciano, MC Nussenzweig, BJ Howell, ... Nature medicine 26 (9), 1339-1350, 2020 | 114 | 2020 |
Resident memory T cells are a cellular reservoir for HIV in the cervical mucosa J Cantero-Pérez, J Grau-Expósito, C Serra-Peinado, DA Rosero, ... Nature communications 10 (1), 4739, 2019 | 101 | 2019 |
A Novel Single-Cell FISH-Flow Assay Identifies Effector Memory CD4+ T cells as a Major Niche for HIV-1 Transcription in HIV-Infected Patients J Grau-Expósito, C Serra-Peinado, L Miguel, J Navarro, A Curran, ... MBio 8 (4), 10.1128/mbio. 00876-17, 2017 | 100 | 2017 |
Potent cell-intrinsic immune responses in dendritic cells facilitate HIV-1-specific T cell immunity in HIV-1 elite controllers E Martin-Gayo, MJ Buzon, Z Ouyang, T Hickman, J Cronin, D Pimenova, ... PLoS pathogens 11 (6), e1004930, 2015 | 97 | 2015 |
Broad activation of latent HIV-1 in vivo K Barton, B Hiener, A Winckelmann, TA Rasmussen, W Shao, K Byth, ... Nature communications 7 (1), 12731, 2016 | 92 | 2016 |
Innate immune activity correlates with CD4 T cell-associated HIV-1 DNA decline during latency-reversing treatment with panobinostat R Olesen, S Vigano, TA Rasmussen, OS Søgaard, Z Ouyang, M Buzon, ... Journal of virology 89 (20), 10176-10189, 2015 | 91 | 2015 |