Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes S Logan, GA Pharaoh, MC Marlin, DR Masser, S Matsuzaki, B Wronowski, ... Molecular metabolism 9, 141-155, 2018 | 148 | 2018 |
Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass B Ahn, G Pharaoh, P Premkumar, K Huseman, R Ranjit, M Kinter, ... Redox biology 17, 47-58, 2018 | 141 | 2018 |
Loss of mitochondrial protease ClpP protects mice from diet‐induced obesity and insulin resistance S Bhaskaran, G Pharaoh, R Ranjit, A Murphy, S Matsuzaki, BC Nair, ... EMBO reports 19 (3), e45009, 2018 | 81 | 2018 |
Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching B Ahn, R Ranjit, P Premkumar, G Pharaoh, KM Piekarz, S Matsuzaki, ... Journal of cachexia, sarcopenia and muscle 10 (2), 411-428, 2019 | 64 | 2019 |
Metabolic and Stress Response Changes Precede Disease Onset in the Spinal Cord of Mutant SOD1 ALS Mice G Pharaoh, K Sataranatarajan, K Street, S Hill, J Gregston, B Ahn, ... Frontiers in Neuroscience 13, 487, 2019 | 54 | 2019 |
AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization A Bastian, S Matsuzaki, KM Humphries, GA Pharaoh, A Doshi, N Zaware, ... Cancer Letters 388, 149-157, 2017 | 45 | 2017 |
Cancer cachexia in a mouse model of oxidative stress JL Brown, MM Lawrence, B Ahn, P Kneis, KM Piekarz, R Qaisar, R Ranjit, ... Journal of cachexia, sarcopenia and muscle 11 (6), 1688-1704, 2020 | 39 | 2020 |
Restoration of Sarcoplasmic Reticulum Ca2+ ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice R Qaisar, G Pharaoh, S Bhaskaran, H Xu, R Ranjit, J Bian, B Ahn, ... International Journal of Molecular Sciences 22 (1), 37, 2020 | 38 | 2020 |
A fish oil diet induces mitochondrial uncoupling and mitochondrial unfolded protein response in epididymal white adipose tissue of mice S Bhaskaran, A Unnikrishnan, R Ranjit, R Qaisar, G Pharaoh, S Matyi, ... Free Radical Biology and Medicine 108, 704-714, 2017 | 35 | 2017 |
Disparate Central and Peripheral Effects of Circulating IGF-1 Deficiency on Tissue Mitochondrial Function G Pharaoh, D Owen, A Yeganeh, P Premkumar, J Farley, S Bhaskaran, ... Molecular Neurobiology 57 (3), 1317-1331, 2020 | 30 | 2020 |
Short-term calorie restriction and 17α-estradiol administration elicit divergent effects on proteostatic processes and protein content in metabolically active tissues BF Miller, GA Pharaoh, KL Hamilton, FF Peelor III, JL Kirkland, ... The Journals of Gerontology: Series A 75 (5), 849-857, 2020 | 29 | 2020 |
Ablation of the mitochondrial complex IV assembly protein Surf1 leads to increased expression of the UPRMT and increased resistance to oxidative stress in … G Pharaoh, D Pulliam, S Hill, K Sataranatarajan, H Van Remmen Redox biology 8, 430-438, 2016 | 27 | 2016 |
Targeting cPLA2 derived lipid hydroperoxides as a potential intervention for sarcopenia G Pharaoh, JL Brown, K Sataranatarajan, P Kneis, J Bian, R Ranjit, ... Scientific reports 10 (1), 13968, 2020 | 23 | 2020 |
Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia K Sataranatarajan, G Pharaoh, JL Brown, R Ranjit, KM Piekarz, K Street, ... GeroScience 42, 1101-1118, 2020 | 23 | 2020 |
Determining the contributions of protein synthesis and breakdown to muscle atrophy requires non‐steady‐state equations KA Kobak, MM Lawrence, G Pharaoh, AK Borowik, FF Peelor III, ... Journal of cachexia, sarcopenia and muscle 12 (6), 1764-1775, 2021 | 22 | 2021 |
Lifelong reduction in complex IV induces tissue‐specific metabolic effects but does not reduce lifespan or healthspan in mice SS Deepa, G Pharaoh, M Kinter, V Diaz, WC Fok, K Riddle, D Pulliam, ... Aging cell 17 (4), e12769, 2018 | 15 | 2018 |
Reduced adenosine diphosphate sensitivity in skeletal muscle mitochondria increases reactive oxygen species production in mouse models of aging and oxidative stress but not … G Pharaoh, J Brown, R Ranjit, Z Ungvari, H Van Remmen JCSM Rapid Communications 4 (1), 75-89, 2021 | 13 | 2021 |
Skeletal muscle mitochondrial interactome remodeling is linked to functional decline in aged female mice AA Bakhtina, GA Pharaoh, MD Campbell, A Keller, RS Stuppard, ... Nature Aging 3 (3), 313-326, 2023 | 6 | 2023 |
The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT) G Pharaoh, V Kamat, S Kannan, RS Stuppard, J Whitson, M Martín-Pérez, ... Geroscience 45 (6), 3529-3548, 2023 | 4 | 2023 |
A novel mitochondrial complex I ROS inhibitor partially improves muscle regeneration in adult but not old mice G Pharaoh, EL Ostrom, R Stuppard, M Campbell, JM Borghardt, M Franti, ... Redox Biology 64, 102770, 2023 | 3 | 2023 |