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Gavin Pharaoh
Gavin Pharaoh
在 uw.edu 的电子邮件经过验证
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引用次数
引用次数
年份
Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes
S Logan, GA Pharaoh, MC Marlin, DR Masser, S Matsuzaki, B Wronowski, ...
Molecular metabolism 9, 141-155, 2018
1482018
Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass
B Ahn, G Pharaoh, P Premkumar, K Huseman, R Ranjit, M Kinter, ...
Redox biology 17, 47-58, 2018
1412018
Loss of mitochondrial protease ClpP protects mice from diet‐induced obesity and insulin resistance
S Bhaskaran, G Pharaoh, R Ranjit, A Murphy, S Matsuzaki, BC Nair, ...
EMBO reports 19 (3), e45009, 2018
812018
Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching
B Ahn, R Ranjit, P Premkumar, G Pharaoh, KM Piekarz, S Matsuzaki, ...
Journal of cachexia, sarcopenia and muscle 10 (2), 411-428, 2019
642019
Metabolic and Stress Response Changes Precede Disease Onset in the Spinal Cord of Mutant SOD1 ALS Mice
G Pharaoh, K Sataranatarajan, K Street, S Hill, J Gregston, B Ahn, ...
Frontiers in Neuroscience 13, 487, 2019
542019
AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization
A Bastian, S Matsuzaki, KM Humphries, GA Pharaoh, A Doshi, N Zaware, ...
Cancer Letters 388, 149-157, 2017
452017
Cancer cachexia in a mouse model of oxidative stress
JL Brown, MM Lawrence, B Ahn, P Kneis, KM Piekarz, R Qaisar, R Ranjit, ...
Journal of cachexia, sarcopenia and muscle 11 (6), 1688-1704, 2020
392020
Restoration of Sarcoplasmic Reticulum Ca2+ ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice
R Qaisar, G Pharaoh, S Bhaskaran, H Xu, R Ranjit, J Bian, B Ahn, ...
International Journal of Molecular Sciences 22 (1), 37, 2020
382020
A fish oil diet induces mitochondrial uncoupling and mitochondrial unfolded protein response in epididymal white adipose tissue of mice
S Bhaskaran, A Unnikrishnan, R Ranjit, R Qaisar, G Pharaoh, S Matyi, ...
Free Radical Biology and Medicine 108, 704-714, 2017
352017
Disparate Central and Peripheral Effects of Circulating IGF-1 Deficiency on Tissue Mitochondrial Function
G Pharaoh, D Owen, A Yeganeh, P Premkumar, J Farley, S Bhaskaran, ...
Molecular Neurobiology 57 (3), 1317-1331, 2020
302020
Short-term calorie restriction and 17α-estradiol administration elicit divergent effects on proteostatic processes and protein content in metabolically active tissues
BF Miller, GA Pharaoh, KL Hamilton, FF Peelor III, JL Kirkland, ...
The Journals of Gerontology: Series A 75 (5), 849-857, 2020
292020
Ablation of the mitochondrial complex IV assembly protein Surf1 leads to increased expression of the UPRMT and increased resistance to oxidative stress in …
G Pharaoh, D Pulliam, S Hill, K Sataranatarajan, H Van Remmen
Redox biology 8, 430-438, 2016
272016
Targeting cPLA2 derived lipid hydroperoxides as a potential intervention for sarcopenia
G Pharaoh, JL Brown, K Sataranatarajan, P Kneis, J Bian, R Ranjit, ...
Scientific reports 10 (1), 13968, 2020
232020
Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia
K Sataranatarajan, G Pharaoh, JL Brown, R Ranjit, KM Piekarz, K Street, ...
GeroScience 42, 1101-1118, 2020
232020
Determining the contributions of protein synthesis and breakdown to muscle atrophy requires non‐steady‐state equations
KA Kobak, MM Lawrence, G Pharaoh, AK Borowik, FF Peelor III, ...
Journal of cachexia, sarcopenia and muscle 12 (6), 1764-1775, 2021
222021
Lifelong reduction in complex IV induces tissue‐specific metabolic effects but does not reduce lifespan or healthspan in mice
SS Deepa, G Pharaoh, M Kinter, V Diaz, WC Fok, K Riddle, D Pulliam, ...
Aging cell 17 (4), e12769, 2018
152018
Reduced adenosine diphosphate sensitivity in skeletal muscle mitochondria increases reactive oxygen species production in mouse models of aging and oxidative stress but not …
G Pharaoh, J Brown, R Ranjit, Z Ungvari, H Van Remmen
JCSM Rapid Communications 4 (1), 75-89, 2021
132021
Skeletal muscle mitochondrial interactome remodeling is linked to functional decline in aged female mice
AA Bakhtina, GA Pharaoh, MD Campbell, A Keller, RS Stuppard, ...
Nature Aging 3 (3), 313-326, 2023
62023
The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT)
G Pharaoh, V Kamat, S Kannan, RS Stuppard, J Whitson, M Martín-Pérez, ...
Geroscience 45 (6), 3529-3548, 2023
42023
A novel mitochondrial complex I ROS inhibitor partially improves muscle regeneration in adult but not old mice
G Pharaoh, EL Ostrom, R Stuppard, M Campbell, JM Borghardt, M Franti, ...
Redox Biology 64, 102770, 2023
32023
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