Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide H Tran, MP Moazami, H Yang, D McKenna-Yasek, CL Douthwright, ... Nature medicine 28 (1), 117-124, 2022 | 113 | 2022 |
Submicrometer nanospray emitters provide new insights into the mechanism of cation adduction to anionic oligonucleotides T Kenderdine, Z Xia, ER Williams, D Fabris Analytical chemistry 90 (22), 13541-13548, 2018 | 40 | 2018 |
High-resolution ion mobility spectrometry-mass spectrometry of isomeric/isobaric ribonucleotide variants T Kenderdine, R Nemati, A Baker, M Palmer, J Ujma, M FitzGibbon, ... Journal of mass spectrometry: JMS 55 (2), e4465, 2020 | 34 | 2020 |
Non-Natural Linker Configuration in 2, 6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins A Sosic, I Saccone, C Carraro, T Kenderdine, E Gamba, G Caliendo, ... Bioconjugate chemistry 29 (7), 2195-2207, 2018 | 10 | 2018 |
The multifaceted roles of mass spectrometric analysis in nucleic acids drug discovery and development T Kenderdine, D Fabris Mass Spectrometry Reviews 42 (4), 1332-1357, 2023 | 5 | 2023 |
Potent mixed backbone antisense oligonucleotide safely suppresses expression of mutant c9orf72 transcripts and polydipeptides: First in human pilot study H Tran, MP Moazami, H Yang, D McKenna-Yasek, C Douthwright, C Pinto, ... Preprint]. doi 21203, 2021 | 5 | 2021 |
Integrating Internal Fragments in the Interpretation of Top-Down Sequencing Data of Larger Oligonucleotides T Kenderdine, W McIntyre, G Yassaghi, D Rollo, A Bunkowski, L Goerlach, ... Journal of the American Society for Mass Spectrometry 34 (10), 2296-2307, 2023 | 4 | 2023 |
Trapped ion mobility mass spectrometry in nucleic acid drug-discovery: revealing conformation-specific preferential binding to regulatory structures of the SARS-CoV-2 genome G. Yassaghi, T. Kenderdine, D. Rollo, J. Kumar, D. Fabris Proceedings of the 71st ASMS Conference on Mass Spectrometry and Allied Topics, 2023 | | 2023 |
Time-course continuous monitoring of digestion reactions increases the coverage afforded by strand-cleavage approaches for the characterization of larger nucleic acids D. Rollo, T. Kenderdine, G. Yassaghi, C. Bell, D. Fabris Proceedings of the 71st ASMS Conference on Mass Spectrometry and Allied Topics, 2023 | | 2023 |
Concerted application of ion mobility and tandem mass spectrometry to differentiate isomeric/isobaric oligonucleotides produced by nuclease digestion of large RNAs T. Kenderdine, D. Rollo, D. Fabris Proceedings of the 71st ASMS Conference on Mass Spectrometry and Allied Topics, 2023 | | 2023 |
Evaluating the merits of high-resolution and TIMS MS in the analysis of complex digestion mixtures from progressively larger nucleic acids D. Rollo, T. Kenderdine, G. Yassaghi, C. Bell, D. Fabris Proceedings of the 70th ASMS Conference on Mass Spectrometry and Allied Topics, 2022 | | 2022 |
Investigating the determinant role of conformation in protein-RNA interactions by native mass spectrometry and trapped ion mobility mass spectrometry G. Yassaghi, J. Kumar, T. Kenderdine, D. Fabris Proceedings of the 70th ASMS Conference on Mass Spectrometry and Allied Topics, 2022 | | 2022 |
Evaluating the contribution of internal fragments to the sequence characterization of progressively larger oligonucleotides and RNAs by top-down mass spectrometry T. Kenderdine, G. Yassaghi, D. Rollo, A. Bunkowski, S. Pengelley, D. Suckau ... Proceedings of the 70th ASMS Conference on Mass Spectrometry and Allied Topics, 2022 | | 2022 |
Potent Mixed Backbone Antisense Oligonucleotide Safety Suppressed Expression of Mutant C9ORF72 Transcripts and Polypeptides: First in Human Pilot Study R Brown, H Tran, M Moazami, H Yang, D McKenna-Yasek, C Douthwright, ... | | 2021 |
Native and trapped ion mobility MS investigation of the effects of small-molecule ligands on protein-RNA interactions in SARS-CoV-2 G.Yassaghi, J. Kumar, T. Kenderdine, D. Rollo, G. Ribaudo, A. Gianoncelli, D ... Proceedings of the 69th ASMS Conference on Mass Spectrometry and Allied Topics, 2021 | | 2021 |
Investigating the Dynamics of Structure-switching RNA Isomers by Trapped Ion Mobility Spectrometry T. Kenderdine, G. Yassaghi, D. Rollo, D. Fabris Proceedings of the 69th ASMS Conference on Mass Spectrometry and Allied Topics, 2021 | | 2021 |
Combining Different Solution Denaturation Techniques to Expand the Limits of Top-Down Analysis of Large Ribonucleic Acids W. McIntyre, T. Kenderdine, B. Toro, R. Treen, A. Sosic, D. Fabris Proceedings of the 67th ASMS Conference on Mass Spectrometry and Allied Topics, 2019 | | 2019 |
Metabolically Labeled Ribonucleotides Enable Multiplexed Quantitative Analysis of the Effects of Stress and Viral Infection by High Resolution Mass Spectrometry T. Kenderdine, R. Nemati, R. Netzband, M. FitzGibbon, W. McIntyre, C. Pager ... Proceedings of the 67th ASMS Conference on Mass Spectrometry and Allied Topics, 2019 | | 2019 |
Ion Mobility and Top-down Mass Spectrometry Provide Unique Insights into the Dynamics of Protein-RNA Interactions T. Kenderdine, W. McIntyre, L. Deng, R. D’Esposito, A. Sosic, D. Fabris Proceedings of the 67th ASMS Conference on Mass Spectrometry and Allied Topics, 2019 | | 2019 |
Utilizing Ion Mobility Spectrometry - Mass Spectrometry and Coarse-Grain Molecular Dynamics to Support Rational Design of Nucleic Acid Nanotechnology R. D’Esposito, T. Kenderdine, B. Toro, S. Ranganathan, P. Li, D. Fabris Proceedings of the 66th ASMS Conference on Mass Spectrometry and Allied Topics, 2018 | | 2018 |