Comprehensive functional genomic resource and integrative model for the human brain D Wang, S Liu, J Warrell, H Won, X Shi, FCP Navarro, D Clarke, M Gu, ... Science 362 (6420), eaat8464, 2018 | 787 | 2018 |
Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions M Gutierrez-Arcelus, N Teslovich, AR Mola, RB Polidoro, A Nathan, H Kim, ... Nature communications 10 (1), 687, 2019 | 133 | 2019 |
IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation F Zhang, JR Mears, L Shakib, JI Beynor, S Shanaj, I Korsunsky, A Nathan, ... Genome medicine 13, 1-17, 2021 | 124 | 2021 |
Efficient and precise single-cell reference atlas mapping with Symphony JB Kang, A Nathan, K Weinand, F Zhang, N Millard, L Rumker, DB Moody, ... Nature communications 12 (1), 5890, 2021 | 110 | 2021 |
Single-cell eQTL models reveal dynamic T cell state dependence of disease loci A Nathan, S Asgari, K Ishigaki, C Valencia, T Amariuta, Y Luo, JI Beynor, ... Nature 606 (7912), 120-128, 2022 | 72 | 2022 |
Presto scales Wilcoxon and auROC analyses to millions of observations I Korsunsky, A Nathan, N Millard, S Raychaudhuri BioRxiv, 653253, 2019 | 61 | 2019 |
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain R Pourhaghighi, PEA Ash, S Phanse, F Goebels, LZM Hu, S Chen, ... Cell systems 10 (4), 333-350. e14, 2020 | 54 | 2020 |
Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease A Nathan, JI Beynor, Y Baglaenko, S Suliman, K Ishigaki, S Asgari, ... Nature Immunology 22 (6), 781-793, 2021 | 48 | 2021 |
Repertoire analyses reveal T cell antigen receptor sequence features that influence T cell fate KA Lagattuta, JB Kang, A Nathan, KE Pauken, AH Jonsson, DA Rao, ... Nature Immunology 23 (3), 446-457, 2022 | 38 | 2022 |
IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation F Zhang, JR Mears, L Shakib, JI Beynor, S Shanaj, I Korsunsky, A Nathan, ... bioRxiv, 2020 | 35 | 2020 |
Design of Protein–Peptide Interaction Modules for Assembling Supramolecular Structures in Vivo and in Vitro EB Speltz, A Nathan, L Regan ACS chemical biology 10 (9), 2108-2115, 2015 | 35 | 2015 |
Co-varying neighborhood analysis identifies cell populations associated with phenotypes of interest from single-cell transcriptomics YA Reshef, L Rumker, JB Kang, A Nathan, I Korsunsky, S Asgari, ... Nature Biotechnology 40 (3), 355-363, 2022 | 31 | 2022 |
Associations between neighborhood‐level factors and opioid‐related mortality: A multi‐level analysis using death certificate data MW Flores, B Lê Cook, B Mullin, G Halperin‐Goldstein, A Nathan, ... Addiction 115 (10), 1878-1889, 2020 | 30 | 2020 |
Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid arthritis F Zhang, AH Jonsson, A Nathan, K Wei, N Millard, Q Xiao, ... BioRxiv, 2022.02. 25.481990, 2022 | 28 | 2022 |
Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders N Akula, S Marenco, K Johnson, N Feng, K Zhu, A Schulmann, W Corona, ... Neuropsychopharmacology 46 (7), 1364-1372, 2021 | 24 | 2021 |
Single-cell genomics meets human genetics ASE Cuomo, A Nathan, S Raychaudhuri, DG MacArthur, JE Powell Nature Reviews Genetics, 1-15, 2023 | 21 | 2023 |
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes F Zhang, AH Jonsson, A Nathan, N Millard, M Curtis, Q Xiao, ... Nature 623 (7987), 616-624, 2023 | 16 | 2023 |
Multimodal single-cell approaches shed light on T cell heterogeneity A Nathan, Y Baglaenko, CY Fonseka, JI Beynor, S Raychaudhuri Current opinion in immunology 61, 17-25, 2019 | 14 | 2019 |
High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership PM Carlucci, J Li, A Fava, KK Deonaraine, D Wofsy, JA James, ... Rheumatology 61 (11), 4335-4343, 2022 | 10 | 2022 |
Multimodal memory T cell profiling identifies a reduction in a polyfunctional Th17 state associated with tuberculosis progression A Nathan, JI Beynor, Y Baglaenko, S Suliman, K Ishigaki, S Asgari, ... bioRxiv, 2020.04. 23.057828, 2020 | 9 | 2020 |