| Signaling from T cell receptors (TCRs) and chimeric antigen receptors (CARs) on T cells L Wu, Q Wei, J Brzostek, NRJ Gascoigne Cellular & Molecular Immunology 17 (6), 600-612, 2020 | 117 | 2020 |
| Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor J Casas, J Brzostek, VI Zarnitsyna, J Hong, Q Wei, JAH Hoerter, G Fu, ... Nature communications 5 (1), 5624, 2014 | 90 | 2014 |
| Canonical T cell receptor docking on peptide–MHC is essential for T cell signaling P Zareie, C Szeto, C Farenc, SD Gunasinghe, EM Kolawole, A Nguyen, ... Science 372 (6546), eabe9124, 2021 | 69 | 2021 |
| Lck bound to coreceptor is less active than free Lck Q Wei, J Brzostek, S Sankaran, J Casas, LSQ Hew, J Yap, X Zhao, ... Proceedings of the National Academy of Sciences 117 (27), 15809-15817, 2020 | 47 | 2020 |
| Targeting CAR to the peptide-MHC complex reveals distinct signaling compared to that of TCR in a jurkat T cell model L Wu, J Brzostek, S Sankaran, Q Wei, J Yap, TYY Tan, J Lai, PA MacAry, ... Cancers 13 (4), 867, 2021 | 15 | 2021 |
| CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance L Wu, J Brzostek, PDS Vale, Q Wei, CKT Koh, JXH Ong, L Wu, JC Tan, ... Cell Reports Medicine 4 (2), 2023 | 9 | 2023 |
| Non-Stimulatory pMHC Enhance CD8 T Cell Effector Functions by Recruiting Coreceptor-Bound Lck X Zhao, LZ Wu, EKY Ng, KWS Leow, Q Wei, NRJ Gascoigne, J Brzostek Frontiers in Immunology 12, 721722, 2021 | 1 | 2021 |
| Utilizing distinct CAR and TCR signaling to generate enhanced cellular immunotherapy NRJ Gascoigne, L Wu, J Brzostek, Q Wei, PDS Vale, CKT Koh, YL Chua, ... The Journal of Immunology 208 (1_Supplement), 122.02-122.02, 2022 | | 2022 |
Nicholas GascoigneProfessor, Department of Microbiology, Yong Loo Lin School of Medicine, National University of在 nus.edu.sg 的电子邮件经过验证
