| Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity T Tadokoro, M Ikeda, T Ide, H Deguchi, S Ikeda, K Okabe, A Ishikita, ... JCI insight 5 (9), 2020 | 483 | 2020 |
| Overexpression of TFAM or Twinkle Increases mtDNA Copy Number and Facilitates Cardioprotection Associated with Limited Mitochondrial Oxidative Stress M Ikeda, T Ide, T Fujino, S Arai, K Saku, T Kakino, H Tyynismaa, ... PloS one 10 (3), e0119687, 2015 | 150 | 2015 |
| Mitochondrial event as an ultimate step in ferroptosis SJ Oh, M Ikeda, T Ide, KY Hur, MS Lee Cell death discovery 8 (1), 414, 2022 | 81 | 2022 |
| Doxorubicin causes ferroptosis and cardiotoxicity by intercalating into mitochondrial DNA and disrupting Alas1-dependent heme synthesis K Abe, M Ikeda, T Ide, T Tadokoro, HD Miyamoto, S Furusawa, Y Tsutsui, ... Science Signaling 15 (758), eabn8017, 2022 | 70 | 2022 |
| Afferent vagal nerve stimulation resets baroreflex neural arc and inhibits sympathetic nerve activity K Saku, T Kishi, K Sakamoto, K Hosokawa, T Sakamoto, Y Murayama, ... Physiological Reports 2 (9), e12136, 2014 | 70 | 2014 |
| Iron overload via heme degradation in the endoplasmic reticulum triggers ferroptosis in myocardial ischemia-reperfusion injury HD Miyamoto, M Ikeda, T Ide, T Tadokoro, S Furusawa, K Abe, K Ishimaru, ... Basic to Translational Science 7 (8), 800-819, 2022 | 68 | 2022 |
| Home‐based cardiac rehabilitation using information and communication technology for heart failure patients with frailty Y Nagatomi, T Ide, T Higuchi, T Nezu, T Fujino, T Tohyama, T Nagata, ... ESC Heart Failure 9 (4), 2407-2418, 2022 | 52 | 2022 |
| The Akt-mTOR axis is a pivotal regulator of eccentric hypertrophy during volume overload M Ikeda, T Ide, T Fujino, Y Matsuo, S Arai, K Saku, T Kakino, Y Oga, ... Scientific reports 5 (1), 15881, 2015 | 52 | 2015 |
| Roxadustat markedly reduces myocardial ischemia reperfusion injury in mice H Deguchi, M Ikeda, T Ide, T Tadokoro, S Ikeda, K Okabe, A Ishikita, ... Circulation Journal 84 (6), 1028-1033, 2020 | 51 | 2020 |
| Blockade of L-type Ca2+ channel attenuates doxorubicin-induced cardiomyopathy via suppression of CaMKII-NF-κB pathway S Ikeda, S Matsushima, K Okabe, M Ikeda, A Ishikita, T Tadokoro, ... Scientific reports 9 (1), 9850, 2019 | 41 | 2019 |
| Total mechanical unloading minimizes metabolic demand of left ventricle and dramatically reduces infarct size in myocardial infarction K Saku, T Kakino, T Arimura, T Sakamoto, T Nishikawa, K Sakamoto, ... PLoS One 11 (4), e0152911, 2016 | 39 | 2016 |
| Machine learning‐based model for predicting 1 year mortality of hospitalized patients with heart failure T Tohyama, T Ide, M Ikeda, H Kaku, N Enzan, S Matsushima, K Funakoshi, ... ESC heart failure 8 (5), 4077-4085, 2021 | 32 | 2021 |
| DPP (Dipeptidyl Peptidase)-4 inhibitor attenuates ang II (Angiotensin II)–induced cardiac hypertrophy via GLP (Glucagon-Like Peptide)-1–dependent suppression of nox … K Okabe, S Matsushima, S Ikeda, M Ikeda, A Ishikita, T Tadokoro, ... Hypertension 75 (4), 991-1001, 2020 | 32 | 2020 |
| Twinkle overexpression prevents cardiac rupture after myocardial infarction by alleviating impaired mitochondrial biogenesis T Inoue, M Ikeda, T Ide, T Fujino, Y Matsuo, S Arai, K Saku, K Sunagawa American Journal of Physiology-Heart and Circulatory Physiology 311 (3 …, 2016 | 31 | 2016 |
| Diffuse alveolar hemorrhage as a complication of dual antiplatelet therapy for acute coronary syndrome M Ikeda, H Tanaka, K Sadamatsu Cardiovascular Revascularization Medicine 12 (6), 407-411, 2011 | 28 | 2011 |
| Excessive hypoxia‐inducible factor‐1α expression induces cardiac rupture via p53‐dependent apoptosis after myocardial infarction M Ikeda, T Ide, T Tadokoro, HD Miyamoto, S Ikeda, K Okabe, A Ishikita, ... Journal of the American Heart Association 10 (17), e020895, 2021 | 26 | 2021 |
| ZBP1 protects against mtDNA-induced myocardial inflammation in failing hearts N Enzan, S Matsushima, S Ikeda, K Okabe, A Ishikita, T Yamamoto, ... Circulation research 132 (9), 1110-1126, 2023 | 24 | 2023 |
| The overexpression of Twinkle helicase ameliorates the progression of cardiac fibrosis and heart failure in pressure overload model in mice A Tanaka, T Ide, T Fujino, K Onitsuka, M Ikeda, T Takehara, Y Hata, ... PLoS One 8 (6), e67642, 2013 | 21 | 2013 |
| Comparative mechanistic study of RPE cell death induced by different oxidative stresses Y Tong, Y Wu, J Ma, M Ikeda, T Ide, CT Griffin, XQ Ding, S Wang Redox Biology 65, 102840, 2023 | 20 | 2023 |
| Ethoxyquin is a competent radical-trapping antioxidant for preventing ferroptosis in doxorubicin cardiotoxicity T Tadokoro, M Ikeda, K Abe, T Ide, HD Miyamoto, S Furusawa, K Ishimaru, ... Journal of Cardiovascular Pharmacology 80 (5), 690-699, 2022 | 19 | 2022 |
