| Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells EP Mimitou, CA Lareau, KY Chen, AL Zorzetto-Fernandes, Y Hao, ... Nature biotechnology 39 (10), 1246-1258, 2021 | 274 | 2021 |
| Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases M Ota, Y Nagafuchi, H Hatano, K Ishigaki, C Terao, Y Takeshima, ... Cell 184 (11), 3006-3021. e17, 2021 | 158 | 2021 |
| Metabolism as a key regulator in the pathogenesis of systemic lupus erythematosus Y Takeshima, Y Iwasaki, K Fujio, K Yamamoto Seminars in Arthritis and Rheumatism 48 (6), 1142-1145, 2019 | 43 | 2019 |
| Basic mechanism of immune system activation by mitochondria Y Iwasaki, Y Takeshima, K Fujio Immunological medicine 43 (4), 142-147, 2020 | 38 | 2020 |
| Distinct transcriptome architectures underlying lupus establishment and exacerbation M Nakano, M Ota, Y Takeshima, Y Iwasaki, H Hatano, Y Nagafuchi, ... Cell 185 (18), 3375-3389. e21, 2022 | 37 | 2022 |
| Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma Y Yasumizu, N Ohkura, H Murata, M Kinoshita, S Funaki, S Nojima, ... Nature Communications 13 (1), 4230, 2022 | 34 | 2022 |
| Immune cell multiomics analysis reveals contribution of oxidative phosphorylation to B-cell functions and organ damage of lupus Y Takeshima, Y Iwasaki, M Nakano, Y Narushima, M Ota, Y Nagafuchi, ... Annals of the Rheumatic Diseases 81 (6), 845-853, 2022 | 30 | 2022 |
| Integrated bulk and single-cell RNA-sequencing identified disease-relevant monocytes and a gene network module underlying systemic sclerosis S Kobayashi, Y Nagafuchi, M Okubo, Y Sugimori, H Shirai, H Hatano, ... Journal of Autoimmunity 116, 102547, 2021 | 26 | 2021 |
| Consecutive BNT162b2 mRNA vaccination induces short-term epigenetic memory in innate immune cells Y Yamaguchi, Y Kato, R Edahiro, JN Søndergaard, T Murakami, S Amiya, ... Jci Insight 7 (22), 2022 | 21 | 2022 |
| Immunomics analysis of rheumatoid arthritis identified precursor dendritic cells as a key cell subset of treatment resistance S Yamada, Y Nagafuchi, M Wang, M Ota, H Hatano, Y Takeshima, ... Annals of the Rheumatic Diseases 82 (6), 809-819, 2023 | 15 | 2023 |
| Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity R Edahiro, Y Shirai, Y Takeshima, S Sakakibara, Y Yamaguchi, ... Nature genetics 55 (5), 753-767, 2023 | 14 | 2023 |
| Delayed lupus nephritis in the course of systemic lupus erythematosus is associated with a poorer treatment response: a multicentre, retrospective cohort study in Japan M Nakano, K Kubo, Y Shirota, Y Iwasaki, Y Takahashi, T Igari, Y Inaba, ... Lupus 28 (9), 1062-1073, 2019 | 12 | 2019 |
| transcriptome and trans-omics analysis of systemic lupus erythematosus K Fujio, Y Takeshima, M Nakano, Y Iwasaki Inflammation and regeneration 40, 1-6, 2020 | 11 | 2020 |
| Successful treatment of acute kidney injury in patients with idiopathic nephrotic syndrome using human atrial natriuretic Peptide K Ueda, J Hirahashi, G Seki, M Tanaka, N Kushida, Y Takeshima, ... Internal Medicine 53 (8), 865-869, 2014 | 10 | 2014 |
| Transcriptome analysis of immune cells from Behçet’s syndrome patients: the importance of IL-17-producing cells and antigen-presenting cells in the pathogenesis of Behçet’s … M Okubo, S Sumitomo, Y Tsuchida, Y Nagafuchi, Y Takeshima, ... Arthritis Research & Therapy 24 (1), 186, 2022 | 9 | 2022 |
| Polymorphic lymphoproliferative disorders in patients with rheumatoid arthritis are associated with a better clinical outcome D Tsukui, H Kanda, A Shinozaki-Ushiku, S Tateishi, Y Takeshima, ... Modern Rheumatology 28 (4), 621-625, 2018 | 9 | 2018 |
| Identifying the most influential gene expression profile in distinguishing ANCA-associated vasculitis from healthy controls H Yanaoka, Y Nagafuchi, N Hanata, Y Takeshima, M Ota, Y Suwa, ... Journal of Autoimmunity 119, 102617, 2021 | 8 | 2021 |
| Transcriptome Profiling of Immune Cell Types in Peripheral Blood Reveals Common and Specific Pathways Involved in the Pathogenesis of Myositis‐Specific Antibody‐Positive … Y Sugimori, Y Iwasaki, Y Takeshima, M Okubo, S Kobayashi, H Hatano, ... ACR Open Rheumatology 5 (2), 93-102, 2023 | 4 | 2023 |
| Dysregulation of the gene signature of effector regulatory T cells in the early phase of systemic sclerosis S Kobayashi, Y Nagafuchi, M Okubo, Y Sugimori, H Hatano, S Yamada, ... Rheumatology 61 (10), 4163-4174, 2022 | 4 | 2022 |
| Single-cell transcriptome landscape of circulating CD4+ T cell populations in autoimmune diseases Y Yasumizu, D Takeuchi, R Morimoto, Y Takeshima, T Okuno, ... Cell Genomics, 2024 | 3 | 2024 |
