Ubiquitin: structures, functions, mechanisms CM Pickart, MJ Eddins Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1695 (1-3), 55-72, 2004 | 1992 | 2004 |
Mms2–Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation MJ Eddins, CM Carlile, KM Gomez, CM Pickart, C Wolberger Nature structural & molecular biology 13 (10), 915-920, 2006 | 378 | 2006 |
A conserved catalytic residue in the ubiquitin‐conjugating enzyme family PY Wu, M Hanlon, M Eddins, C Tsui, RS Rogers, JP Jensen, MJ Matunis, ... The EMBO journal, 2003 | 231 | 2003 |
Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH MJ Eddins, R Varadan, D Fushman, CM Pickart, C Wolberger Journal of molecular biology 367 (1), 204-211, 2007 | 228 | 2007 |
A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein A Tang, Z Chen, KS Cox, HP Su, C Callahan, A Fridman, L Zhang, ... Nature communications 10 (1), 4153, 2019 | 84 | 2019 |
Targeting the ubiquitin E3 ligase MuRF1 to inhibit muscle atrophy MJ Eddins, JG Marblestone, KG Suresh Kumar, CA Leach, DE Sterner, ... Cell biochemistry and biophysics 60, 113-118, 2011 | 70 | 2011 |
Comprehensive ubiquitin E2 profiling of ten ubiquitin E3 ligases JG Marblestone, S Butt, DM McKelvey, DE Sterner, MR Mattern, ... Cell biochemistry and biophysics 67, 161-167, 2013 | 30 | 2013 |
Crystallization and low-resolution structure of an effector-caspase/P35 complex: similarities and differences to an initiator-caspase/P35 complex MJ Eddins, D Lemongello, PD Friesen, AJ Fisher Acta Crystallographica Section D: Biological Crystallography 58 (2), 299-302, 2002 | 27 | 2002 |
Bioluminescence assay platform for selective and sensitive detection of Ub/Ubl proteases SJ Orcutt, J Wu, MJ Eddins, CA Leach, JE Strickler Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (11), 2079-2086, 2012 | 25 | 2012 |
Novel approach for characterizing ubiquitin E3 ligase function JG Marblestone, KG Suresh Kumar, MJ Eddins, CA Leach, DE Sterner, ... Journal of Biomolecular Screening 15 (10), 1220-1228, 2010 | 19 | 2010 |
Discovery of a new class of integrin antibodies for fibrosis J Zhang, T Wang, A Saigal, J Johnson, J Morrisson, S Tabrizifard, ... Scientific Reports 11 (1), 2118, 2021 | 15 | 2021 |
Discovery of therapeutic deubiquitylase effector molecules: current perspectives B Nicholson, S Kumar, S Agarwal, MJ Eddins, JG Marblestone, J Wu, ... Journal of biomolecular screening 19 (7), 989-999, 2014 | 14 | 2014 |
Protein microarrays for the identification of praja1 e3 ubiquitin ligase substrates CM Loch, MJ Eddins, JE Strickler Cell biochemistry and biophysics 60, 127-135, 2011 | 14 | 2011 |
Profiling of hMPV F-specific antibodies isolated from human memory B cells X Xiao, A Fridman, L Zhang, P Pristatsky, E Durr, M Minnier, A Tang, ... Nature Communications 13 (1), 2546, 2022 | 10 | 2022 |
Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases VA Kleiner, T O. Fischmann, JA Howe, DC Beshore, MJ Eddins, Y Hou, ... Communications Biology 6 (1), 649, 2023 | 7 | 2023 |
Di-and poly-ubiquitin deubiquitinase substrates and uses thereof D Chelur, M Eddins, C Leach, SJ Orcutt, RJ Peroutka, J Strickler, Y Yan, ... US Patent 8,518,660, 2013 | 7 | 2013 |
Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants SA Hollingsworth, CL Noland, K Vroom, A Saha, M Sam, Q Gao, H Zhou, ... Scientific Reports 13 (1), 13668, 2023 | 6 | 2023 |
Proteasome inhibitors versus E3 ligase inhibitors for cancer therapy MR Mattern, MJ Eddins, S Agarwal, DE Sterner, MP Kodrasov, ... Resistance to Proteasome Inhibitors in Cancer: Molecular Mechanisms and …, 2014 | 3 | 2014 |
Ubiquitin‐conjugating Enzymes MJ Eddins, CM Pickart Protein Science Encyclopedia: online, 102-134, 2008 | 2 | 2008 |
Abstract A21: Inhibition of USP7 for the treatment of multiple myeloma and other malignancies. B Nicholson, MP Kodrasov, JP LaRocque, MJ Eddins, S Kumar, ... Clinical Cancer Research 21 (17_Supplement), A21-A21, 2015 | 1 | 2015 |