| The eIF2α kinases: their structures and functions N Donnelly, AM Gorman, S Gupta, A Samali Cellular and molecular life sciences 70, 3493-3511, 2013 | 920 | 2013 |
| PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress T Verfaillie, N Rubio, AD Garg, G Bultynck, R Rizzuto, JP Decuypere, ... Cell Death & Differentiation 19 (11), 1880-1891, 2012 | 764 | 2012 |
| Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice JM Jones, P Datta, SM Srinivasula, W Ji, S Gupta, ZJ Zhang, E Davies, ... Nature 425 (6959), 721-727, 2003 | 465 | 2003 |
| Targeting the endoplasmic reticulum-stress response as an anticancer strategy SJM Healy, AM Gorman, P Mousavi-Shafaei, S Gupta, A Samali European journal of pharmacology 625 (1-3), 234-246, 2009 | 392 | 2009 |
| Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders KM Doyle, D Kennedy, AM Gorman, S Gupta, SJM Healy, A Samali Journal of cellular and molecular medicine 15 (10), 2025-2039, 2011 | 376 | 2011 |
| Methods for monitoring endoplasmic reticulum stress and the unfolded protein response A Samali, U FitzGerald, S Deegan, S Gupta International journal of cell biology 2010, 2010 | 345 | 2010 |
| Bcl-2 family on guard at the ER E Szegezdi, DC MacDonald, T Ní Chonghaile, S Gupta, A Samali American Journal of Physiology-Cell Physiology 296 (5), C941-C953, 2009 | 319 | 2009 |
| HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1α-XBP1 signaling through a physical interaction S Gupta, A Deepti, S Deegan, F Lisbona, C Hetz, A Samali PLoS biology 8 (7), e1000410, 2010 | 288 | 2010 |
| The mitochondrial death pathway: a promising therapeutic target in diseases S Gupta, GEN Kass, E Szegezdi, B Joseph Journal of cellular and molecular medicine 13 (6), 1004-1033, 2009 | 281 | 2009 |
| Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2 SM Srinivasula, S Gupta, P Datta, ZJ Zhang, R Hegde, NE Cheong, ... Journal of Biological Chemistry 278 (34), 31469-31472, 2003 | 269 | 2003 |
| Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death L Cilenti, MM Soundarapandian, GA Kyriazis, V Stratico, S Singh, S Gupta, ... Journal of Biological Chemistry 279 (48), 50295-50301, 2004 | 228 | 2004 |
| cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas S Hu, MQ Du, SM Park, A Alcivar, L Qu, S Gupta, J Tang, M Baens, H Ye, ... The Journal of clinical investigation 116 (1), 174-181, 2006 | 124 | 2006 |
| Direct transcriptional activation of human caspase-1 by tumor suppressor p53 S Gupta, V Radha, Y Furukawa, G Swarup Journal of Biological Chemistry 276 (14), 10585-10588, 2001 | 116 | 2001 |
| The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity S Gupta, R Singh, P Datta, ZJ Zhang, C Orr, Z Lu, G DuBois, AS Zervos, ... Journal of Biological Chemistry 279 (44), 45844-45854, 2004 | 110 | 2004 |
| Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis S Gupta, DE Read, A Deepti, K Cawley, A Gupta, D Oommen, T Verfaillie, ... Cell death & disease 3 (6), e333-e333, 2012 | 107 | 2012 |
| Mechanisms of ER stress-mediated mitochondrial membrane permeabilization S Gupta, L Cuffe, E Szegezdi, SE Logue, C Neary, S Healy, A Samali International journal of cell biology 2010, 2010 | 95 | 2010 |
| Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis S Sadasivam, S Gupta, V Radha, K Batta, TK Kundu, G Swarup Oncogene 24 (4), 627-636, 2005 | 75 | 2005 |
| A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy S Deegan, I Koryga, SA Glynn, S Gupta, AM Gorman, A Samali Biochemical and biophysical research communications 456 (1), 305-311, 2015 | 69 | 2015 |
| Assays for detecting the unfolded protein response K Cawley, S Deegan, A Samali, S Gupta Methods in enzymology 490, 31-51, 2011 | 58 | 2011 |
| Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions S Deegan, S Saveljeva, SE Logue, K Pakos-Zebrucka, S Gupta, ... Autophagy 10 (11), 1921-1936, 2014 | 56 | 2014 |
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