Single-cell chromatin accessibility reveals principles of regulatory variation JD Buenrostro, B Wu, UM Litzenburger, D Ruff, ML Gonzales, MP Snyder, ... Nature 523 (7561), 486-490, 2015 | 1996 | 2015 |
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor CA Opitz, UM Litzenburger, F Sahm, M Ott, I Tritschler, S Trump, ... Nature 478 (7368), 197-203, 2011 | 1834 | 2011 |
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor CA Opitz, UM Litzenburger, F Sahm, M Ott, I Tritschler, S Trump, ... Nature 478 (7368), 197-203, 2011 | 1834 | 2011 |
Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2, 3-dioxygenase-1 via … CA Opitz, UM Litzenburger, C Lutz, TV Lanz, I Tritschler, A Köppel, ... Stem cells 27 (4), 909-919, 2009 | 389 | 2009 |
Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR UM Litzenburger, CA Opitz, F Sahm, KJ Rauschenbach, S Trump, ... Oncotarget 5 (4), 1038, 2014 | 294 | 2014 |
ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing X Chen, Y Shen, W Draper, JD Buenrostro, U Litzenburger, SW Cho, ... Nature methods 13 (12), 1013-1020, 2016 | 222 | 2016 |
The indoleamine-2, 3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells CA Opitz, UM Litzenburger, U Opitz, F Sahm, K Ochs, C Lutz, W Wick, ... PloS one 6 (5), e19823, 2011 | 173 | 2011 |
Single-cell epigenomic variability reveals functional cancer heterogeneity UM Litzenburger, JD Buenrostro, B Wu, Y Shen, NC Sheffield, A Kathiria, ... Genome biology 18, 1-12, 2017 | 110 | 2017 |
Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA J Xu, K Nuno, UM Litzenburger, Y Qi, MR Corces, R Majeti, HY Chang Elife 8, e45105, 2019 | 109 | 2019 |
Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity X Chen, UM Litzenburger, Y Wei, AN Schep, EL LaGory, H Choudhry, ... Nature communications 9 (1), 4590, 2018 | 83 | 2018 |
Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma T Purzner, J Purzner, T Buckstaff, G Cozza, S Gholamin, JM Rusert, ... Science signaling 11 (547), eaau5147, 2018 | 70 | 2018 |
Suppression of TDO‐mediated tryptophan catabolism in glioblastoma cells by a steroid‐responsive FKBP52‐dependent pathway M Ott, UM Litzenburger, KJ Rauschenbach, L Bunse, K Ochs, F Sahm, ... Glia 63 (1), 78-90, 2015 | 62 | 2015 |
Promotion of glioblastoma cell motility by enhancer of zeste homolog 2 (EZH2) is mediated by AXL receptor kinase M Ott, UM Litzenburger, F Sahm, KJ Rauschenbach, R Tudoran, ... Public Library of Science 7 (10), e47663, 2012 | 57 | 2012 |
Protein kinase Cβ as a therapeutic target stabilizing blood–brain barrier disruption in experimental autoimmune encephalomyelitis TV Lanz, S Becker, M Osswald, S Bittner, MK Schuhmann, CA Opitz, ... Proceedings of the National Academy of Sciences 110 (36), 14735-14740, 2013 | 54 | 2013 |
Prrx1 fibroblasts represent a pro-fibrotic lineage in the mouse ventral dermis T Leavitt, MS Hu, MR Borrelli, M Januszyk, JT Garcia, RC Ransom, ... Cell Reports 33 (6), 2020 | 49 | 2020 |
Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia Y Li, JJ Gruber, UM Litzenburger, Y Zhou, YR Miao, EL LaGory, AM Li, ... Cell Death & Disease 11 (2), 102, 2020 | 45 | 2020 |
Suppression of human CD4+ T cell activation by 3, 4-dimethoxycinnamonyl-anthranilic acid (tranilast) is mediated by CXCL9 and CXCL10 A Hertenstein, T Schumacher, U Litzenburger, CA Opitz, CS Falk, ... Biochemical pharmacology 82 (6), 632-641, 2011 | 34 | 2011 |
Suppression of human CD4+ T cell activation by 3, 4-dimethoxycinnamonyl-anthranilic acid (tranilast) is mediated by CXCL9 and CXCL10 A Hertenstein, T Schumacher, U Litzenburger, CA Opitz, CS Falk, ... Biochemical pharmacology 82 (6), 632-641, 2011 | 34 | 2011 |
The aryl hydrocarbon receptor in tumor immunity M Platten, U Litzenburger, W Wick Oncoimmunology 1 (3), 396-397, 2012 | 32 | 2012 |
ATAC Primer Tool for targeted analysis of accessible chromatin KE Yost, AC Carter, J Xu, U Litzenburger, HY Chang Nature methods 15 (5), 304-305, 2018 | 15 | 2018 |