| Systems biotechnology for strain improvement SY Lee, DY Lee, TY Kim Trends in biotechnology 23 (7), 349-358, 2005 | 429 | 2005 |
| Metabolic engineering of Escherichia coli for enhanced production of succinic acid, based on genome comparison and in silico gene knockout simulation SJ Lee, DY Lee, TY Kim, BH Kim, J Lee, SY Lee Appl. Environ. Microbiol. 71 (12), 7880-7887, 2005 | 374 | 2005 |
| MEMOTE for standardized genome-scale metabolic model testing C Lieven, ME Beber, BG Olivier, FT Bergmann, M Ataman, P Babaei, ... Nature biotechnology 38 (3), 272-276, 2020 | 355 | 2020 |
| Recon 2.2: from reconstruction to model of human metabolism N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ... Metabolomics 12 (7), 109, 2016 | 317 | 2016 |
| A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... Cell Systems 3 (5), 434-443. e8, 2016 | 245 | 2016 |
| Combined in silico modeling and metabolomics analysis to characterize fed‐batch CHO cell culture S Selvarasu, YS Ho, WPK Chong, NSC Wong, FNK Yusufi, YY Lee, ... Biotechnology and bioengineering 109 (6), 1415-1429, 2012 | 241 | 2012 |
| Synthetic fusion protein design and applications K Yu, C Liu, BG Kim, DY Lee Biotechnology advances 33 (1), 155-164, 2015 | 240 | 2015 |
| Metabolite essentiality elucidates robustness of Escherichia coli metabolism PJ Kim, DY Lee, TY Kim, KH Lee, H Jeong, SY Lee, S Park Proceedings of the National Academy of Sciences 104 (34), 13638-13642, 2007 | 167 | 2007 |
| MetaFluxNet: the management of metabolic reaction information and quantitative metabolic flux analysis DY Lee, H Yun, S Park, SY Lee Bioinformatics 19 (16), 2144-2146, 2003 | 164 | 2003 |
| N-Glycosylation design and control of therapeutic monoclonal antibodies S Sha, C Agarabi, K Brorson, DY Lee, S Yoon Trends in biotechnology 34 (10), 835-846, 2016 | 159 | 2016 |
| Genome and evolution of the shade‐requiring medicinal herb Panax ginseng NH Kim, M Jayakodi, SC Lee, BS Choi, W Jang, J Lee, HH Kim, ... Plant biotechnology journal 16 (11), 1904-1917, 2018 | 158 | 2018 |
| Codon Optimization OnLine (COOL): a web-based multi-objective optimization platform for synthetic gene design JX Chin, BKS Chung, DY Lee Bioinformatics 30 (15), 2210-2212, 2014 | 156 | 2014 |
| Genome-scale metabolic reconstruction and in silico analysis of methylotrophic yeast Pichia pastoris for strain improvement BKS Chung, S Selvarasu, A Camattari, J Ryu, H Lee, J Ahn, H Lee, ... Microbial cell factories 9 (1), 50, 2010 | 156 | 2010 |
| Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: overexpression of malate dehydrogenase II WPK Chong, SG Reddy, FNK Yusufi, DY Lee, NSC Wong, CK Heng, ... Journal of biotechnology 147 (2), 116-121, 2010 | 122 | 2010 |
| Software applications for flux balance analysis M Lakshmanan, G Koh, BKS Chung, DY Lee Briefings in bioinformatics 15 (1), 108-122, 2014 | 116 | 2014 |
| LC‐MS‐based metabolic characterization of high monoclonal antibody‐producing Chinese hamster ovary cells WPK Chong, SH Thng, AP Hiu, DY Lee, ECY Chan, YS Ho Biotechnology and bioengineering 109 (12), 3103-3111, 2012 | 105 | 2012 |
| Computational codon optimization of synthetic gene for protein expression BKS Chung, DY Lee BMC systems biology 6 (1), 134, 2012 | 105 | 2012 |
| Mammalian Systems Biotechnology Reveals Global Cellular Adaptations in a Recombinant CHO Cell Line FNK Yusufi, M Lakshmanan, YS Ho, BLW Loo, P Ariyaratne, Y Yang, ... Cell Systems 4 (5), 530-542. e6, 2017 | 103 | 2017 |
| Genome‐scale modeling and in silico analysis of ethanologenic bacteria Zymomonas mobilis H Widiastuti, JY Kim, S Selvarasu, IA Karimi, H Kim, JS Seo, DY Lee Biotechnology and bioengineering 108 (3), 655-665, 2011 | 101 | 2011 |
| Metabolomics profiling of extracellular metabolites in recombinant Chinese Hamster Ovary fed‐batch culture WPK Chong, LT Goh, SG Reddy, FNK Yusufi, DY Lee, NSC Wong, ... Rapid Communications in Mass Spectrometry 23 (23), 3763-3771, 2009 | 92 | 2009 |
