Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice J Xiao, C Wang, JC Yao, Y Alippe, C Xu, D Kress, R Civitelli, Y Abu-Amer, ... PLoS biology 16 (11), e3000047, 2018 | 129 | 2018 |
A metabolic synthetic lethal strategy with arginine deprivation and chloroquine leads to cell death in ASS1-deficient sarcomas GR Bean, JC Kremer, BC Prudner, AD Schenone, JC Yao, MB Schultze, ... Cell death & disease 7 (10), e2406, 2016 | 89 | 2016 |
Skp2-mediated RagA ubiquitination elicits a negative feedback to prevent amino-acid-dependent mTORC1 hyperactivation by recruiting GATOR1 G Jin, SW Lee, X Zhang, Z Cai, Y Gao, PC Chou, AH Rezaeian, F Han, ... Molecular cell 58 (6), 989-1000, 2015 | 81 | 2015 |
MIR142 Loss-of-Function Mutations Derepress ASH1L to Increase HOXA Gene Expression and Promote LeukemogenesisMIR142 Mutations Promote AML by Increasing HOXA via ASH1L MC Trissal, TN Wong, JC Yao, R Ramaswamy, I Kuo, J Baty, Y Sun, G Jih, ... Cancer research 78 (13), 3510-3521, 2018 | 50 | 2018 |
Radiation causes tissue damage by dysregulating inflammasome–gasdermin D signaling in both host and transplanted cells J Xiao, C Wang, JC Yao, Y Alippe, T Yang, D Kress, K Sun, KL Kostecki, ... PLoS biology 18 (8), e3000807, 2020 | 39 | 2020 |
Concise review: The malignant hematopoietic stem cell niche JC Yao, DC Link Stem Cells 35 (1), 3-8, 2017 | 25 | 2017 |
TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment BV Le, P Podszywalow-Bartnicka, S Maifrede, K Sullivan-Reed, ... Cell reports 33 (1), 108221, 2020 | 21 | 2020 |
TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche JC Yao, KA Oetjen, T Wang, H Xu, G Abou-Ezzi, JR Krambs, S Uttarwar, ... The Journal of Clinical Investigation, 2022 | 19 | 2022 |
TLR7/8 agonist treatment induces an increase in bone marrow resident dendritic cells and hematopoietic progenitor expansion and mobilization S Li, JC Yao, JT Li, AP Schmidt, DC Link Experimental Hematology 96, 35-43. e7, 2021 | 11 | 2021 |
IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function S Li, JC Yao, KA Oetjen, JR Krambs, J Xia, J Zhang, AP Schmidt, ... Blood, 2022 | 7 | 2022 |
TGF-β Signaling Contributes to Myelofibrosis and Clonal Dominance of Myeloproliferative Neoplasms JC Yao, G Abou Ezzi, JR Krambs, S Uttarwar, EJ Duncavage, DC Link Blood 134, 470, 2019 | 6 | 2019 |
Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions JR Krambs, G Abou Ezzi, JC Yao, DC Link Plos one 15 (5), e0233751, 2020 | 5 | 2020 |
TGF-β Signaling Contributes to the Clonal Dominance of Jak2V617F Hematopoietic Stem/Progenitor Cells JC Yao, DC Link Blood 136, 11, 2020 | 3 | 2020 |
MIR142 Loss-of-Function Mutations Promote Leukemogenesis through Derepression of ASH1L Resulting in Increased HOX Gene Expression JC Yao, TN Wong, M Trissal, R Ramaswamy, Y Sun, TJ Ley, PR Reddy, ... Blood 128 (22), 2718-2718, 2016 | 2 | 2016 |
TGF-β Signaling in Stromal Cells Contributes to Myelofibrosis, but Not Niche Disruption, in Myeloproliferative Neoplasms JC Yao, DC Link Blood 138, 1463, 2021 | 1 | 2021 |
TGF-Beta Signaling in Mesenchymal Stromal Cells Contributes to Myelofibrosis but Not Hematopoietic Phenotypes in Myeloproliferative Neoplasms JC Yao, G Abou Ezzi, JR Krambs, EJ Duncavage, DC Link Blood 132 (Supplement 1), 3053-3053, 2018 | 1 | 2018 |
Contribution of TGF-b Signaling to the Pathogenesis of Myeloproliferative Neoplasms JC Yao | | 2021 |
Canonical Signaling By TGF Family Members in Mesenchymal Stromal Cells Is Dispensable for Hematopoietic Niche Maintenance Under Basal and Stress Conditions JR Krambs, G Abou Ezzi, JC Yao, JT Li, DC Link Blood 134, 1209, 2019 | | 2019 |
MIR142 loss-of-function mutations promote leukemogenesis through derepression of ASH1L resulting in increased HOX gene expression JC Yao, TN Wong, M Trissal, R Ramaswamy, Y Sun, PR Reddy, DC Link Cancer Research 77 (13_Supplement), 3042-3042, 2017 | | 2017 |
Loss-of-Function Mutations of MIR142 May Contribute to Leukemogenesis By Expanding the Pool of Myeloid-Biased HSCs JC Yao, TN Wong, M Trissal, Y Sun, TJ Ley, P Reddy, DC Link Blood 126 (23), 1254-1254, 2015 | | 2015 |