Antigen identification for orphan T cell receptors expressed on tumor-infiltrating lymphocytes MH Gee, A Han, SM Lofgren, JF Beausang, JL Mendoza, ME Birnbaum, ... Cell 172 (3), 549-563. e16, 2018 | 280 | 2018 |
Isolation of a structural mechanism for uncoupling T cell receptor signaling from peptide-MHC binding LV Sibener, RA Fernandes, EM Kolawole, CB Carbone, F Liu, D McAffee, ... Cell 174 (3), 672-687. e27, 2018 | 267 | 2018 |
Novel and shared neoantigen derived from histone 3 variant H3. 3K27M mutation for glioma T cell therapy ZS Chheda, G Kohanbash, K Okada, N Jahan, J Sidney, M Pecoraro, ... Journal of Experimental Medicine 215 (1), 141-157, 2018 | 211 | 2018 |
Sequence and structural analyses reveal distinct and highly diverse human CD8+ TCR repertoires to immunodominant viral antigens G Chen, X Yang, A Ko, X Sun, M Gao, Y Zhang, A Shi, RA Mariuzza, ... Cell reports 19 (3), 569-583, 2017 | 125 | 2017 |
Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery SH Chiou, D Tseng, A Reuben, V Mallajosyula, IS Molina, S Conley, ... Immunity 54 (3), 586-602. e8, 2021 | 95 | 2021 |
Immune receptor inhibition through enforced phosphatase recruitment RA Fernandes, L Su, Y Nishiga, J Ren, AM Bhuiyan, N Cheng, CJ Kuo, ... Nature 586 (7831), 779-784, 2020 | 74 | 2020 |
Antimicrobial peptides from the venoms of Vespa bicolor Fabricius W Chen, X Yang, X Yang, L Zhai, Z Lu, J Liu, H Yu Peptides 29 (11), 1887-1892, 2008 | 64 | 2008 |
Tuning T cell receptor sensitivity through catch bond engineering X Zhao, EM Kolawole, W Chan, Y Feng, X Yang, MH Gee, KM Jude, ... Science 376 (6589), eabl5282, 2022 | 63 | 2022 |
Autoimmunity-associated T cell receptors recognize HLA-B* 27-bound peptides X Yang, LI Garner, IV Zvyagin, MA Paley, EA Komech, KM Jude, X Zhao, ... Nature 612 (7941), 771-777, 2022 | 50 | 2022 |
A serine proteinase inhibitor from frog eggs with bacteriostatic activity Y Han, H Yu, X Yang, HH Rees, J Liu, R Lai Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2008 | 47 | 2008 |
Recognition of the Thomsen-Friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor M Luo, CA Velikovsky, X Yang, MA Siddiqui, X Hong, JJ Barchi, ... Journal of Biological Chemistry 288 (32), 23597-23606, 2013 | 42 | 2013 |
Structural basis for clonal diversity of the public T cell response to a dominant human cytomegalovirus epitope X Yang, M Gao, G Chen, BG Pierce, J Lu, N Weng, RA Mariuzza Journal of Biological Chemistry 290 (48), 29106-29119, 2015 | 38 | 2015 |
A novel serine protease inhibitor from the venom of Vespa bicolor Fabricius X Yang, Y Wang, Z Lu, L Zhai, J Jiang, J Liu, H Yu Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2009 | 34 | 2009 |
Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo RA Fernandes, C Li, G Wang, X Yang, CS Savvides, CR Glassman, ... Elife 9, e58463, 2020 | 32 | 2020 |
Structural basis for clonal diversity of the human T-cell response to a dominant influenza virus epitope X Yang, G Chen, N Weng, RA Mariuzza Journal of Biological Chemistry 292 (45), 18618-18627, 2017 | 29 | 2017 |
Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro MH Gee, LV Sibener, ME Birnbaum, KM Jude, X Yang, RA Fernandes, ... Proceedings of the National Academy of Sciences 115 (31), E7369-E7378, 2018 | 27 | 2018 |
Facile repurposing of peptide–MHC-restricted antibodies for cancer immunotherapy X Yang, D Nishimiya, S Löchte, KM Jude, M Borowska, CS Savvides, ... Nature Biotechnology 41 (7), 932-943, 2023 | 16 | 2023 |
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes M Ali, E Giannakopoulou, Y Li, M Lehander, S Virding Culleton, W Yang, ... Nature biotechnology 40 (4), 488-498, 2022 | 16 | 2022 |
Pre–T-cell receptor binds MHC: Implications for thymocyte signaling and selection X Yang, RA Mariuzza Proceedings of the National Academy of Sciences 112 (27), 8166-8167, 2015 | 13 | 2015 |
Facile method for screening clinical T cell receptors for off-target peptide-HLA reactivity MH Gee, X Yang, KC Garcia BioRxiv, 472480, 2018 | 8 | 2018 |