| SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate D Olagnier, E Farahani, J Thyrsted, J Blay-Cadanet, A Herengt, M Idorn, ... Nature communications 11 (1), 4938, 2020 | 367 | 2020 |
| IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP KL Jønsson, A Laustsen, C Krapp, KA Skipper, K Thavachelvam, D Hotter, ... Nature communications 8 (1), 14391, 2017 | 296 | 2017 |
| Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING CK Holm, SB Jensen, MR Jakobsen, N Cheshenko, KA Horan, ... Nature immunology 13 (8), 737-743, 2012 | 264 | 2012 |
| Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming D Olagnier, AM Brandtoft, C Gunderstofte, NL Villadsen, C Krapp, ... Nature communications 9 (1), 3506, 2018 | 242 | 2018 |
| Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors KA Horan, K Hansen, MR Jakobsen, CK Holm, S Søby, L Unterholzner, ... The Journal of Immunology 190 (5), 2311-2319, 2013 | 229 | 2013 |
| Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses CK Holm, SH Rahbek, HH Gad, RO Bak, MR Jakobsen, Z Jiang, ... Nature communications 7 (1), 10680, 2016 | 228 | 2016 |
| Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling AL Hansen, GJ Buchan, M Rühl, K Mukai, SR Salvatore, E Ogawa, ... Proceedings of the National Academy of Sciences 115 (33), E7768-E7775, 2018 | 202 | 2018 |
| TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice LS Reinert, L Harder, CK Holm, MB Iversen, KA Horan, ... The Journal of clinical investigation 122 (4), 1368-1376, 2012 | 190 | 2012 |
| The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy TW Kragstrup, K Otkjaer, C Holm, A Jørgensen, M Hokland, L Iversen, ... Cytokine 41 (1), 16-23, 2008 | 137 | 2008 |
| Increased interleukin 21 (IL-21) and IL-23 are associated with increased disease activity and with radiographic status in patients with early rheumatoid arthritis TK Rasmussen, T Andersen, M Hvid, ML Hetland, K Hørslev-Petersen, ... The Journal of rheumatology 37 (10), 2014-2020, 2010 | 136 | 2010 |
| Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes SB Rasmussen, KA Horan, CK Holm, AJ Stranks, TC Mettenleiter, ... The journal of immunology 187 (10), 5268-5276, 2011 | 128 | 2011 |
| Intracellular bacteria engage a STING–TBK1–MVB12b pathway to enable paracrine cGAS–STING signalling R Nandakumar, R Tschismarov, F Meissner, T Prabakaran, ... Nature microbiology 4 (4), 701-713, 2019 | 119 | 2019 |
| SARS‐CoV‐2 evades immune detection in alveolar macrophages L Dalskov, M Møhlenberg, J Thyrsted, J Blay‐Cadanet, ET Poulsen, ... EMBO reports 21 (12), e51252, 2020 | 88 | 2020 |
| An innate antiviral pathway acting before interferons at epithelial surfaces MB Iversen, LS Reinert, MK Thomsen, I Bagdonaite, R Nandakumar, ... Nature immunology 17 (2), 150-158, 2016 | 82 | 2016 |
| DNA recognition in immunity and disease CK Holm, SR Paludan, KA Fitzgerald Current opinion in immunology 25 (1), 13-18, 2013 | 74 | 2013 |
| Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus TK Rasmussen, T Andersen, RO Bak, G Yiu, CM Sørensen, ... Arthritis research & therapy 17, 1-12, 2015 | 70 | 2015 |
| TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS‐CoV‐2 infection RM van der Sluis, LB Cham, A Gris‐Oliver, KR Gammelgaard, ... The EMBO journal 41 (10), e109622, 2022 | 69 | 2022 |
| Finite-size scaling study of the three-dimensional classical Heisenberg model C Holm, W Janke Physics Letters A 173 (1), 8-12, 1993 | 69 | 1993 |
| T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication RK Berg, SH Rahbek, E Kofod-Olsen, CK Holm, J Melchjorsen, ... PLoS One 9 (1), e84513, 2014 | 67 | 2014 |
| STING palmitoylation as a therapeutic target AL Hansen, K Mukai, FJ Schopfer, T Taguchi, CK Holm Cellular & molecular immunology 16 (3), 236-241, 2019 | 62 | 2019 |
