Drug interactions with lipid‐lowering drugs: mechanisms and clinical relevance PJ Neuvonen, M Niemi, JT Backman Clinical Pharmacology & Therapeutics 80 (6), 565-581, 2006 | 1056 | 2006 |
Pharmacokinetic interactions with rifampicin: clinical relevance M Niemi, JT Backman, MF Fromm, PJ Neuvonen, KT Kivistö Clinical pharmacokinetics 42, 819-850, 2003 | 880 | 2003 |
High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1) M Niemi, E Schaeffeler, T Lang, MF Fromm, M Neuvonen, C Kyrklund, ... Pharmacogenetics and Genomics 14 (7), 429-440, 2004 | 514 | 2004 |
Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole KT Olkkola, JT Backman, PJ Neuvonen Clinical Pharmacology & Therapeutics 55 (5), 481-485, 1994 | 460 | 1994 |
Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics M Niemi, JT Backman, LI Kajosaari, JB Leathart, M Neuvonen, AK Daly, ... Clinical Pharmacology & Therapeutics 77 (6), 468-478, 2005 | 434 | 2005 |
Gemfibrozil greatly increases plasma concentrations of cerivastatin JT Backman, C Kyrklund, M Neuvonen, PJ Neuvonen Clinical Pharmacology & Therapeutics 72 (6), 685-691, 2002 | 403 | 2002 |
Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil … M Niemi, JT Backman, M Neuvonen, PJ Neuvonen Diabetologia 46, 347-351, 2003 | 319 | 2003 |
Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers M Shyamsundar, STW McKeown, CM O'Kane, TR Craig, V Brown, ... American journal of respiratory and critical care medicine 179 (12), 1107-1114, 2009 | 318 | 2009 |
Plasma concentrations of active simvastatin acid are increased by gemfibrozil JT Backman, C Kyrklund, KT Kivistö, JS Wang, PJ Neuvonen Clinical Pharmacology & Therapeutics 68 (2), 122-129, 2000 | 318 | 2000 |
Rifampin drastically reduces plasma concentrations and effects of oral midazolam JT Backman, KT Olkkola, PJ Neuvonen Clinical pharmacology & therapeutics 59 (1), 7-13, 1996 | 308 | 1996 |
The area under the plasma concentration–time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin JT Backman, KT Kivistö, KT Olkkola, PJ Neuvonen European journal of clinical pharmacology 54, 53-58, 1998 | 296 | 1998 |
Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin PJ Neuvonen, JT Backman, M Niemi Clinical pharmacokinetics 47, 463-474, 2008 | 280 | 2008 |
Expression of cyclooxygenase 1 and cyclooxygenase 2 in human synovial tissue: differential elevation of cyclooxygenase 2 in inflammatory joint diseases I Siegle, T Klein, JT Backman, JG Saal, RM Nüsing, P Fritz Arthritis & Rheumatism: Official Journal of the American College of …, 1998 | 280 | 1998 |
Cyclosporine markedly raises the plasma concentrations of repaglinide LI Kajosaari, M Niemi, M Neuvonen, J Laitila, PJ Neuvonen, JT Backman Clinical Pharmacology & Therapeutics 78 (4), 388-399, 2005 | 256 | 2005 |
Gemfibrozil considerably increases the plasma concentrations of rosiglitazone M Niemi, JT Backman, M Granfors, J Laitila, M Neuvonen, PJ Neuvonen Diabetologia 46, 1319-1323, 2003 | 255 | 2003 |
The role of β-glucuronidase in drug disposition and drug targeting in humans B Sperker, JT Backman, HK Kroemer Clinical pharmacokinetics 33, 18-31, 1997 | 240 | 1997 |
Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide M Niemi, JB Leathart, M Neuvonen, JT Backman, AK Daly, PJ Neuvonen Clinical Pharmacology & Therapeutics 74 (4), 380-387, 2003 | 228 | 2003 |
Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate C Kyrklund, JT Backman, KT Kivistö, M Neuvonen, J Laitila, PJ Neuvonen Clinical Pharmacology & Therapeutics 69 (5), 340-345, 2001 | 225 | 2001 |
Dose of midazolam should be reduced during diltiazem and verapamil treatments. JT Backman, KT Olkkola, K Aranko, JJ Himberg, PJ Neuvonen British journal of clinical pharmacology 37 (3), 221-225, 1994 | 224 | 1994 |
Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance C Kyrklund, JT Backman, M Neuvonen, PJ Neuvonen Clinical Pharmacology & Therapeutics 73 (6), 538-544, 2003 | 220 | 2003 |