The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes DC Berwick, I Hers, KJ Heesom, SK Moule, JM Tavareá Journal of Biological Chemistry 277 (37), 33895-33900, 2002 | 466 | 2002 |
Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles DC Berwick, GC Dell, GI Welsh, KJ Heesom, I Hers, LM Fletcher, ... Journal of cell science 117 (25), 5985-5993, 2004 | 185 | 2004 |
A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation BMH Law, VA Spain, VHL Leinster, R Chia, A Beilina, HJ Cho, ... Journal of Biological Chemistry 289 (2), 895-908, 2014 | 170 | 2014 |
Role of protein kinase B in insulin-regulated glucose uptake GI Welsh, I Hers, DC Berwick, G Dell, M Wherlock, R Birkin, S Leney, ... Biochemical Society Transactions 33 (2), 346-349, 2005 | 162 | 2005 |
The importance of Wnt signalling for neurodegeneration in Parkinson's disease DC Berwick, K Harvey Biochemical Society Transactions 40 (5), 1123-1128, 2012 | 153 | 2012 |
LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same DC Berwick, GR Heaton, S Azeggagh, K Harvey Molecular Neurodegeneration 14, 1-22, 2019 | 143 | 2019 |
LRRK2 signaling pathways: the key to unlocking neurodegeneration? DC Berwick, K Harvey Trends in cell biology 21 (5), 257-265, 2011 | 120 | 2011 |
LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6 DC Berwick, K Harvey Human molecular genetics 21 (22), 4966-4979, 2012 | 119 | 2012 |
The regulation and deregulation of Wnt signaling by PARK genes in health and disease DC Berwick, K Harvey Journal of molecular cell biology 6 (1), 3-12, 2014 | 80 | 2014 |
Protective LRRK2 R1398H variant enhances GTPase and Wnt signaling activity J Nixon-Abell, DC Berwick, S Grannó, VA Spain, C Blackstone, K Harvey Frontiers in molecular neuroscience 9, 18, 2016 | 76 | 2016 |
Identifying protein kinase substrates: hunting for the organ-grinder's monkeys DC Berwick, JM Tavaré Trends in biochemical sciences 29 (5), 227-232, 2004 | 76 | 2004 |
The relevance of α-KLOTHO to the central nervous system: some key questions MM Cararo-Lopes, CHY Mazucanti, C Scavone, EM Kawamoto, ... Ageing research reviews 36, 137-148, 2017 | 70 | 2017 |
Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling DC Berwick, B Javaheri, A Wetzel, M Hopkinson, J Nixon-Abell, S Grannò, ... Molecular neurodegeneration 12, 1-17, 2017 | 69 | 2017 |
LRRK2: an éminence grise of Wnt-mediated neurogenesis? DC Berwick, K Harvey Frontiers in cellular neuroscience 7, 82, 2013 | 45 | 2013 |
The development of inhibitors of leucine‐rich repeat kinase 2 (LRRK2) as a therapeutic strategy for Parkinson's disease: the current state of play S Azeggagh, DC Berwick British journal of pharmacology 179 (8), 1478-1495, 2022 | 44 | 2022 |
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus S Granno, J Nixon-Abell, DC Berwick, J Tosh, G Heaton, S Almudimeegh, ... Scientific reports 9 (1), 7322, 2019 | 32 | 2019 |
L'RRK de Triomphe: a solution for LRRK2 GTPase activity? J Nixon-Abell, DC Berwick, K Harvey Biochemical Society Transactions 44 (6), 1625-1634, 2016 | 20 | 2016 |
A simple technique for the prediction of interacting proteins reveals a direct Brn-3a-androgen receptor interaction DC Berwick, JKJ Diss, VS Budhram-Mahadeo, DS Latchman Journal of biological chemistry 285 (20), 15286-15295, 2010 | 20 | 2010 |
Regulation Of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation DC Berwick, M Calissano, JD Corness, SJ Cook, DS Latchman Brain research 1256, 8-18, 2009 | 12 | 2009 |
Building Bridges In Neuropharmacology: New therapeutic approaches for psychiatric and neurodegenerative disorders A Bailey, DC Berwick, R Camarini, C Scavone British Journal of Pharmacology 179 (8), 1475-1477, 2022 | 2 | 2022 |