Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor γ activation has coordinate effects on gene expression in multiple … JM Way, WW Harrington, KK Brown, WK Gottschalk, SS Sundseth, ... Endocrinology 142 (3), 1269-1277, 2001 | 454 | 2001 |
Novel loci and pathways significantly associated with longevity YI Zeng, C Nie, J Min, X Liu, M Li, H Chen, H Xu, M Wang, T Ni, Y Li, ... Scientific reports 6 (1), 21243, 2016 | 187 | 2016 |
Insulin and glucosamine infusions increase O-linked N-acetyl-glucosamine in skeletal muscle proteins in vivo H Yki-Järvinen, A Virkamäki, MC Daniels, D McClain, WK Gottschalk Metabolism 47 (4), 449-455, 1998 | 146 | 1998 |
The cis-regulatory effect of an Alzheimer’s disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes C Linnertz, L Anderson, W Gottschalk, D Crenshaw, MW Lutz, J Allen, ... Alzheimer's & Dementia 10 (5), 541-551, 2014 | 93 | 2014 |
The broad impact of TOM40 on neurodegenerative diseases in aging WK Gottschalk, MW Lutz, YT He, AM Saunders, DK Burns, AD Roses, ... Journal of Parkinson's disease and Alzheimer's disease 1 (1), 2014 | 92 | 2014 |
Using genetics to enable studies on the prevention of Alzheimer's disease DG Crenshaw, WK Gottschalk, MW Lutz, I Grossman, AM Saunders, ... Clinical Pharmacology & Therapeutics 93 (2), 177-185, 2013 | 77 | 2013 |
TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial AD Roses, MW Lutz, DG Crenshaw, I Grossman, AM Saunders, ... Alzheimer's & Dementia 9 (2), 132-136, 2013 | 71 | 2013 |
The pathway mediating insulin's effects on pyruvate dehydrogenase bypasses the insulin receptor tyrosine kinase WK Gottschalk Journal of Biological Chemistry 266 (14), 8814-8819, 1991 | 71 | 1991 |
Sex differences in genetic associations with longevity Y Zeng, C Nie, J Min, H Chen, X Liu, R Ye, Z Chen, C Bai, E Xie, Z Yin, ... JAMA network open 1 (4), e181670-e181670, 2018 | 70 | 2018 |
Understanding the genetics of APOE and TOMM40 and role of mitochondrial structure and function in clinical pharmacology of Alzheimer's disease A Roses, S Sundseth, A Saunders, W Gottschalk, D Burns, M Lutz Alzheimer's & Dementia 12 (6), 687-694, 2016 | 67 | 2016 |
Preclinical developments in type 2 diabetes JM Lenhard, WK Gottschalk Advanced drug delivery reviews 54 (9), 1199-1212, 2002 | 65 | 2002 |
The biological foundation of the genetic association of TOMM40 with late-onset Alzheimer's disease K Zeitlow, L Charlambous, I Ng, S Gagrani, M Mihovilovic, S Luo, DL Rock, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (11 …, 2017 | 58 | 2017 |
UDP-N-acetylglucosamine transferase and glutamine: fructose 6-phosphate amidotransferase activities in insulin-sensitive tissues H Yki-Järvinen, C Vogt, P Iozzo, R Pipek, MC Daniels, A Virkamäki, ... Diabetologia 40, 76-81, 1997 | 54 | 1997 |
The insulinomimetic effects of the polar head group of an insulin-sensitive glycophospholipid on pyruvate dehydrogenase in both subcellular and whole cell assays WK Gottschalk, L Jarett Archives of biochemistry and biophysics 261 (1), 175-185, 1988 | 54 | 1988 |
The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes O Chiba-Falek, WK Gottschalk, MW Lutz Alzheimer's & Dementia 14 (5), 692-698, 2018 | 49 | 2018 |
Reassessment of pioglitazone for Alzheimer’s disease AM Saunders, DK Burns, WK Gottschalk Frontiers in neuroscience 15, 666958, 2021 | 37 | 2021 |
African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles AD Roses, MW Lutz, AM Saunders, D Goldgaber, R Saul, SS Sundseth, ... Alzheimer's & Dementia 10 (6), 592-601. e2, 2014 | 37 | 2014 |
The effects of PPARγ on the regulation of the TOMM40-APOE-C1 genes cluster S Subramanian, WK Gottschalk, SY Kim, AD Roses, O Chiba-Falek Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (3), 810-816, 2017 | 33 | 2017 |
The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist KP Madauss, WA Burkhart, TG Consler, DJ Cowan, WK Gottschalk, ... Acta Crystallographica Section D: Biological Crystallography 65 (5), 449-461, 2009 | 32 | 2009 |
Intracellular mediators of insulin action WK Gottschalk, L Jarett Diabetes/Metabolism Reviews 1 (3), 229-259, 1985 | 31 | 1985 |