关注
Marc Lecomte
Marc Lecomte
Principal DMPK Scientist. Merck Healthcare KGaA
在 merckgroup.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin.
M Lecomte, O Laneuville, C Ji, DL DeWitt, WL Smith
Journal of Biological Chemistry 269 (18), 13207-13215, 1994
5021994
Reaction of metformin with dicarbonyl compounds. Possible implication in the inhibition of advanced glycation end product formation
D Ruggiero-Lopez, M Lecomte, G Moinet, G Patereau, M Lagarde, ...
Biochemical pharmacology 58 (11), 1765-1773, 1999
3161999
Involvement of Arginine 120, Glutamate 524, and Tyrosine 355 in the Binding of Arachidonate and 2-Phenylpropionic Acid Inhibitors to the Cyclooxygenase Active Site of Ovine …
DK Bhattacharyya, M Lecomte, CJ Rieke, RM Garavito, WL Smith
Journal of Biological Chemistry 271 (4), 2179-2184, 1996
2381996
Role of the cyclic adenosine 3', 5'-monophosphate and the phosphatidylinositol-Ca2+ cascades in mediating the effects of thyrotropin and iodide on hormone synthesis and …
B Corvilain, E Laurent, M Lecomte, J Vansande, JE Dumont
The Journal of Clinical Endocrinology & Metabolism 79 (1), 152-159, 1994
1741994
Advanced glycation end-products induce apoptosis of bovine retinal pericytes in culture: involvement of diacylglycerol/ceramide production and oxidative stress induction
U Denis, M Lecomte, C Paget, D Ruggiero, N Wiernsperger, M Lagarde
Free Radical Biology and Medicine 33 (2), 236-247, 2002
1592002
Selective inhibition of prostaglandin endoperoxide synthase-1 (cyclooxygenase-1) by valerylsalicylic acid
DK Bhattacharyya, M Lecomte, J Dunn, DJ Morgans, WL Smith
Archives of biochemistry and biophysics 317 (1), 19-24, 1995
1271995
Modification of enzymatic antioxidants in retinal microvascular cells by glucose or advanced glycation end products
C Paget, M Lecomte, D Ruggiero, N Wiernsperger, M Lagarde
Free Radical Biology and Medicine 25 (1), 121-129, 1998
1101998
Albumin antioxidant capacity is modified by methylglyoxal
P Faure, L Troncy, M Lecomte, N Wiernsperger, M Lagarde, D Ruggiero, ...
Diabetes & metabolism 31 (2), 169-177, 2005
922005
The formation of tubular structures by endothelial cells is under the control of fibrinolysis and mechanical factors
B Vailhé, M Lecomte, N Wiernsperger, L Tranqui
Angiogenesis 2, 331-344, 1998
711998
Pattern of protein phosphorylation in aortic endothelial cells. Modulation by adenine nucleotides and bradykinin.
D Demolle, M Lecomte, JM Boeynaems
Journal of Biological Chemistry 263 (34), 18459-18465, 1988
641988
Docosahexaenoic Acid Is a Major n‐3 Polyunsaturated Fatty Acid in Bovine Retinal Microvessels
M Lecomte, C Paget, D Ruggiero, N Wiernsperger, M Lagarde
Journal of neurochemistry 66 (5), 2160-2167, 1996
631996
In vitro and in vivo alterations of enzymatic glycosylation in diabetes
N Rellier, D Ruggiero-Lopez, M Lecomte, M Lagarde, N Wiernsperger
Life sciences 64 (17), 1571-1583, 1999
621999
Involvement of cell-cell interactions in the pathogenesis of diabetic retinopathy.
D Ruggiero, M Lecomte, E Michoud, M Lagarde, N Wiernsperger
Diabetes & metabolism 23 (1), 30-42, 1997
591997
Growth modulation of retinal microvascular cells by early and advanced glycation products
D Ruggiero-Lopez, N Rellier, M Lecomte, M Lagarde, N Wiernsperger
Diabetes research and clinical practice 34 (3), 135-142, 1997
491997
Dual regulation of glutathione peroxidase by docosahexaenoic acid in endothelial cells depending on concentration and vascular bed origin
I Delton-Vandenbroucke, E Véricel, C Januel, M Carreras, M Lecomte, ...
Free Radical Biology and Medicine 30 (8), 895-904, 2001
372001
Covalent binding of arachidonic acid metabolites to human platelet proteins. Identification of prostaglandin H synthase as one of the modified substrates.
M Lecomte, R Lecocq, JE Dumont, JM Boeynaems
Journal of Biological Chemistry 265 (9), 5178-5187, 1990
371990
Discovery and structure-guided drug design of inhibitors of 11β-hydroxysteroid-dehydrogenase type I based on a spiro-carboxamide scaffold
F Lepifre, S Christmann-Franck, D Roche, C Leriche, D Carniato, ...
Bioorganic & medicinal chemistry letters 19 (13), 3682-3685, 2009
292009
Involvement of caspase-10 in advanced glycation end-product-induced apoptosis of bovine retinal pericytes in culture
M Lecomte, U Denis, D Ruggiero, M Lagarde, N Wiernsperger
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1689 (3), 202-211, 2004
282004
Improved prediction of in vivo supersaturation and precipitation of poorly soluble weakly basic drugs using a biorelevant bicarbonate buffer in a gastrointestinal transfer model
C Jede, C Wagner, H Kubas, M Weigandt, C Weber, M Lecomte, L Badolo, ...
Molecular Pharmaceutics 16 (9), 3938-3947, 2019
262019
In vivo effect of 8-epi-PGF2α on retinal circulation in diabetic and non-diabetic rats
E Michoud, M Lecomte, M Lagarde, N Wiernsperger
Prostaglandins, leukotrienes and essential fatty acids 59 (6), 349-355, 1998
261998
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