Structural and functional roles of Daxx SIM phosphorylation in SUMO paralog-selective binding and apoptosis modulation CC Chang, MT Naik, YS Huang, JC Jeng, PH Liao, HY Kuo, CC Ho, ... Molecular cell 42 (1), 62-74, 2011 | 199 | 2011 |
Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease N Pishesha, AM Bilate, MC Wibowo, NJ Huang, Z Li, R Deshycka, ... Proceedings of the National Academy of Sciences 114 (12), 3157-3162, 2017 | 156 | 2017 |
Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin K Matsuura, NJ Huang, K Cocce, L Zhang, S Kornbluth Oncogene 36 (12), 1698-1706, 2017 | 76 | 2017 |
The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1 NJ Huang, L Zhang, W Tang, C Chen, CS Yang, S Kornbluth Journal of Cell Biology 197 (3), 361-367, 2012 | 75 | 2012 |
Ubiquitylation of p53 by the APC/C inhibitor Trim39 L Zhang, NJ Huang, C Chen, W Tang, S Kornbluth Proceedings of the National Academy of Sciences 109 (51), 20931-20936, 2012 | 61 | 2012 |
Fatty acid synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death CS Yang, K Matsuura, NJ Huang, AC Robeson, B Huang, L Zhang, ... Oncogene 34 (25), 3264-3272, 2015 | 58 | 2015 |
Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin NJ Huang, N Pishesha, J Mukherjee, S Zhang, R Deshycka, V Sudaryo, ... Nature Communications 8 (1), 423, 2017 | 56 | 2017 |
Enhanced phosphocholine metabolism is essential for terminal erythropoiesis NJ Huang, YC Lin, CY Lin, N Pishesha, CA Lewis, E Freinkman, ... Blood, The Journal of the American Society of Hematology 131 (26), 2955-2966, 2018 | 46 | 2018 |
Suppression of DNA-damage checkpoint signaling by Rsk-mediated phosphorylation of Mre11 C Chen, L Zhang, NJ Huang, B Huang, S Kornbluth Proceedings of the National Academy of Sciences 110 (51), 20605-20610, 2013 | 39 | 2013 |
Microfluidic label-free bioprocessing of human reticulocytes from erythroid culture KK Zeming, Y Sato, L Yin, NJ Huang, LH Wong, HL Loo, YB Lim, CT Lim, ... Lab on a Chip 20 (18), 3445-3460, 2020 | 23 | 2020 |
Metabolic control of Ca2+/calmodulin-dependent protein kinase II (CaMKII)-mediated caspase-2 suppression by the B55β/protein phosphatase 2A (PP2A) B Huang, CS Yang, J Wojton, NJ Huang, C Chen, EJ Soderblom, L Zhang, ... Journal of Biological Chemistry 289 (52), 35882-35890, 2014 | 23 | 2014 |
Phosphocholine accumulation and PHOSPHO1 depletion promote adipose tissue thermogenesis M Jiang, TE Chavarria, B Yuan, HF Lodish, NJ Huang Proceedings of the National Academy of Sciences 117 (26), 15055-15065, 2020 | 13 | 2020 |
Efficient CRISPR-Cas9 mediated gene disruption in primary erythroid progenitor cells H Li, J Shi, NJ Huang, N Pishesha, A Natarajan, JC Eng, HF Lodish haematologica 101 (6), e216, 2016 | 9 | 2016 |
Production of enucleated red blood cells and uses thereof H Lodish, NJ Huang, N Pishesha, HL Ploegh, C Shoemaker US Patent App. 16/641,203, 2020 | 2 | 2020 |
Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity R Deshycka, V Sudaryo, NJ Huang, Y Xie, LY Smeding, MK Choi, ... Plos one 16 (11), e0259353, 2021 | 1 | 2021 |