An essential role for monocyte chemoattractant protein‐1 in alcoholic liver injury: Regulation of proinflammatory cytokines and hepatic steatosis in mice P Mandrekar, A Ambade, A Lim, G Szabo, D Catalano Hepatology 54 (6), 2185-2197, 2011 | 316 | 2011 |
Oxidative stress and inflammation: essential partners in alcoholic liver disease A Ambade, P Mandrekar International journal of hepatology 2012 (1), 853175, 2012 | 252 | 2012 |
Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol‐Induced Liver Damage, Steatosis, and Inflammation in Mice A Ambade, P Lowe, K Kodys, D Catalano, B Gyongyosi, Y Cho, ... Hepatology 69 (3), 1105-1121, 2019 | 172 | 2019 |
Cutting edge: Necrosis activates the NLRP3 inflammasome H Li, A Ambade, F Re The Journal of Immunology 183 (3), 1528-1532, 2009 | 167 | 2009 |
Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high … M Ganz, TN Bukong, T Csak, B Saha, JK Park, A Ambade, K Kodys, ... Journal of Translational Medicine 13, 193, 2015 | 140 | 2015 |
MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and Patients From Ethanol-Induced Liver Disease A Satishchandran, A Ambade, S Rao, YC Hsueh, A Iracheta-Vellve, ... Gastroenterology 154 (1), 238-252. e7, 2018 | 139 | 2018 |
Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use TN Bukong, Y Cho, A Iracheta-Vellve, B Saha, P Lowe, A Adejumo, I Furi, ... Journal of hepatology 69 (5), 1145-1154, 2018 | 120 | 2018 |
Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice PP Lowe, B Gyongyosi, A Satishchandran, A Iracheta-Vellve, A Ambade, ... PLoS One 12 (3), e0174544, 2017 | 118 | 2017 |
Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression PP Lowe, B Gyongyosi, A Satishchandran, A Iracheta-Vellve, Y Cho, ... Journal of neuroinflammation 15, 1-12, 2018 | 110 | 2018 |
Macrophage‐Specific Hypoxia‐Inducible Factor‐1α Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis X Wang, M de Carvalho Ribeiro, A Iracheta‐Vellve, P Lowe, A Ambade, ... Hepatology 69 (2), 545-563, 2019 | 99 | 2019 |
Hepatocellular carcinoma is accelerated by NASH involving M2 macrophage polarization mediated by hif-1 α induced IL-10 A Ambade, A Satishchandran, B Saha, B Gyongyosi, P Lowe, K Kodys, ... OncoImmunology 5 (10), e1221557, 2016 | 95 | 2016 |
Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide‐induced liver injury in mice A Ambade, D Catalano, A Lim, P Mandrekar Hepatology 55 (5), 1585-1595, 2012 | 94 | 2012 |
FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice A Iracheta‐Vellve, CD Calenda, J Petrasek, A Ambade, K Kodys, ... Hepatology communications 2 (11), 1379-1391, 2018 | 90 | 2018 |
Alcohol‐induced miR‐155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease S Bala, T Csak, K Kodys, D Catalano, A Ambade, I Furi, P Lowe, Y Cho, ... Journal of leukocyte biology 102 (2), 487-498, 2017 | 85 | 2017 |
Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1α activation A Ambade, A Satishchandran, G Szabo Scientific reports 6 (1), 21340, 2016 | 81 | 2016 |
Moderate Alcohol Induces Stress Proteins HSF1 and hsp70 and Inhibits Proinflammatory Cytokines Resulting in Endotoxin Tolerance S Muralidharan, A Ambade, MA Fulham, J Deshpande, D Catalano, ... The Journal of Immunology 193 (4), 1975-1987, 2014 | 81 | 2014 |
Pharmacological Inhibition of Heat Shock Protein 90 Alleviates Steatosis and Macrophage Activation in Murine Acute and Chronic Alcoholic Liver Injury A Ambade, D Catalano, A Lim, A Kopoyan, SA Shaffer, P Mandrekar Journal of Hepatology 61 (4), 903-11, 2014 | 77* | 2014 |
Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease TN Bukong, A Iracheta‐Vellve, B Saha, A Ambade, A Satishchandran, ... Hepatology 64 (4), 1057-1071, 2016 | 70 | 2016 |
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations PP Lowe, C Morel, A Ambade, A Iracheta-Vellve, E Kwiatkowski, ... Journal of neuroinflammation 17, 1-18, 2020 | 54 | 2020 |
Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease A Ambade, A Satishchandran, B Gyongyosi, P Lowe, G Szabo World Journal of Gastroenterology 22 (16), 4091, 2016 | 51 | 2016 |